Perimembranous-type renal amyloidosis: a peculiar form of AL amyloidosis.

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is a cytokine which plays an important role in the division, proliferation and migration of endothelial cells. In the kidney, VEGF expression is found in glomerular podocytes and in tubular epithelial cells, which may result in acute inflammatory reactions. METHODS:...

journal_title：Nephron

authors： Prakash S,Agrawal S,Kumar S,Prasad N

更新日期：2015-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) is a histological pattern of podocyte and glomerulus injury. FSGS can be primary and secondary to other diseases or due to a genetic cause. Strikingly, genetic causes for adult-onset FSGS are often overlooked, likely because identifying patients with genetic forms of FSGS base...

journal_title：Nephron

authors： Snoek R,Nguyen TQ,van der Zwaag B,van Zuilen AD,Kruis HME,van Gils-Verrij LA,Goldschmeding R,Knoers NVAM,Rookmaaker MB,van Eerde AM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. METHODS:We performed an observational study on patients (≥18 years old) who had been on HD for ...

journal_title：Nephron

authors： Lim Y,Yang G,Cho S,Kim SR,Lee YJ

更新日期：2020-01-01 00:00:00

abstract：:A four-year-old male with steroid refractory nephrotic syndrome was found to have diffuse deposition of alpha 2-macroglobulin (alpha 2M) in the glomeruli which showed diffuse mesangial proliferation and partial hyalinization by light microscopy. Camostat mesylate, a commercially available synthetic proteinase inhibito...

journal_title：Nephron

authors： Asami T,Ohsawa S,Tomisawa S,Hashimoto K,Toyabe S,Sakai K

更新日期：1992-01-01 00:00:00

abstract：:It has been assumed, but not documented, that hypercalcemia induces an appreciable reduction in the serum anion gap (AG) because it represents an increase in the level of unmeasured cations. To test this question, we retrospectively compared the data of 59 hypercalcemic patients with malignancy [group 1, serum Ca 13.3...

journal_title：Nephron

authors： Oster JR,Gutierrez R,Schlessinger FB,Taylor A,Federman DG,Vaamonde CA

更新日期：1990-01-01 00:00:00

abstract：:Previously, we have shown that insulin binding (IB) to erythrocytes was decreased in uremic patients and that hemodialysis corrected the receptor defect. In the present study cross-incubation experiments were performed using uremic and control erythrocytes and plasma. Incubation of control erythrocytes with uremic pla...

journal_title：Nephron

authors： Milutinović S,Breyer D,Janković N,Molnar V,Stefović A,Rocić B

更新日期：1983-01-01 00:00:00

abstract：:In earlier studies, we have shown that induction of passive Heymann nephritis (PHN) by intrarenal infusion of anti-Fx1A antibodies provokes an immediate fall in renal blood flow (RBF) and glomerular filtration rate (GFR). This was probably mediated via the complement system, as infusion of the F(ab')2 fraction of anti...

journal_title：Nephron

authors： Sekse I,Iversen BM,Daha MR,Ofstad J

更新日期：1992-01-01 00:00:00

abstract：:Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but ...

journal_title：Nephron

authors： Carrara C,Abbate M,Sabadini E,Remuzzi G

更新日期：2017-01-01 00:00:00

abstract：:The local cutaneous inflammatory response to DMCB sensitization was positive in only 35% of 20 uremic patients, and the delayed skin reaction was positive in only 15%. The reaction to DMCB challenge was markedly delayed in some patients. Improved response to DNCB re-challenge followed levamisole administration in only...

journal_title：Nephron

authors： Modai D,Sagi DB,Maor J

更新日期：1980-01-01 00:00:00

abstract：:Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...

journal_title：Nephron

authors： Lobo PI,Okusa MD

更新日期：2019-01-01 00:00:00

abstract：:Forced migration is on the rise, mainly from the Middle East to western countries, resulting in unprecedented moral, political, and economic challenges for both refugees and host communities. Recent research showed that refugees represent around 1.5% of the dialysis population in several European and Middle Eastern co...

journal_title：Nephron

authors： Sekkarie MA,Abdel-Rahman EM

更新日期：2017-01-01 00:00:00

abstract：:15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and p...

journal_title：Nephron

authors： Oh MS,Carroll HJ

更新日期：1978-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：:The sera of 64 patients with extracapillary glomerulonephritis were investigated by enzyme-linked immunosorbent assay for the presence of antibody to human neutrophil myeloperoxidase (MPO). In all, circulating anti-MPO were found in 30% and antineutrophil cytoplasm antibodies (ANCA) detected by indirect immunofluoresc...

journal_title：Nephron

authors： Nässberger L,Sjöholm AG,Thysell H

更新日期：1990-01-01 00:00:00

abstract：AIM:Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. METHODS:We performed immunohistochemical staining using anti-SV40 ...

journal_title：Nephron

authors： Masutani K,Matsukuma Y,Tsuchimoto A,Okabe Y,Doi A,Kaku K,Nakamura M,Nakano T,Tsuruya K,Kitazono T

更新日期：2020-01-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:The introduction of automated biopsy devices and the localization of the kidney by ultrasound were aimed at optimizing efficacy and safety of the percutaneous renal biopsy procedure. We evaluated these technological advances in our renal biopsies performed in children. METHODS:We sequentially used the Silve...

journal_title：Nephron

authors： Feneberg R,Schaefer F,Zieger B,Waldherr R,Mehls O,Schärer K

更新日期：1998-08-01 00:00:00

abstract：:We encountered 11 patients with aluminum-associated bone disease (AABD), and treated them with deferoxamine (DFO). In 3 patients, a second bone biopsy was done during DFO treatment. Clinical features of AABD were compared with surgically proven secondary hyperparathyroidism (2 degrees HPT) with osteitis fibrosa on X-r...

journal_title：Nephron

authors： Iwamoto N,Ono T,Yamazaki S,Fukuda T,Kondo M,Yamamoto N,Hiratake Y,Masugi Y,Kubo Y,Hino M

更新日期：1986-01-01 00:00:00

abstract：:The variations of ionized and total calcium concentrations were studied during haemodialysis with high flux membrane using dialysate calcium concentrations of 1.63 and 1.76 mmol/l. The changes in ionized and total calcium were related to the predialytic calcium concentration difference between plasma and dialysate. Th...

journal_title：Nephron

authors： Kancir CB,Wanscher M,Petersen PH

更新日期：1988-01-01 00:00:00

abstract：:Secondary hyperparathyroidism is common in chronic renal failure and is due to inadequate synthesis of calcitriol, the active metabolite of vitamin D. Intravenous administration of alphacalcidol, a synthetic analogue which is metabolized to calcitriol, was given during 12 weeks to 51 patients on chronic hemodialysis i...

journal_title：Nephron

authors： Ljunghall S,Althoff P,Fellström B,Marjanovic B,Nisell J,Weiss L,Wide L

更新日期：1990-01-01 00:00:00

abstract：:In an attempt to clarify the renal involvement induced by human parvovirus B19 (HPB19) infection, we investigated 6 adult patients with transient urinary abnormalities followed by erythema infectiosum. All patients had HPB19-specific IgM antibody and showed mild proteinuria of 0.2-1.2 g/day with or without microscopic...

journal_title：Nephron

authors： Takeda S,Takaeda C,Takazakura E,Haratake J

更新日期：2001-11-01 00:00:00

abstract：:We studied the effects of oral furosemide, 80 mg/day for 7 days, on the response of urinary excretion of phosphate and cyclic AMP to exogenous parathyroid extract (PTE) in 6 normal subjects. All 6 subjects had marked increases in urinary calcium and a significant increase in urinary cyclic AMP from the control to the ...

journal_title：Nephron

authors： Fujita T,Delea CS,Bartter FC

更新日期：1985-01-01 00:00:00

abstract：:In 2014 57.5% of HD patients and 62.7% of PD patients achieved the audit measure for phosphate. 29.0% of HD and 30.3% of PD patients had a serum phosphate above the audit standard range. 79.1% of HD and 79.7% of PD patients had adjusted calcium between 2.2–2.5 mmol/L. 57.4% of HD and 65.0% of PD patients had a serum P...

journal_title：Nephron

authors： Nicholas J,Evans R,Shaw C,Dawnay A

更新日期：2016-01-01 00:00:00

abstract：:We studied the effects of mid-term enalapril administration on protein-load-induced renal responses in 10 patients with early chronic renal failure (serum creatinine 2.70 +/- 1.0 mg/dl). The oral protein load was performed twice, before and after a 10-day therapy with enalapril. Glomerular filtration rate (125I-iothal...

journal_title：Nephron

authors： Oldrizzi L,Rugiu C,Maschio G

更新日期：1989-01-01 00:00:00

abstract：:Using a 2-hour 47Ca absorption test, significant depression of active calcium absorption was demonstrated in 48 vitamin D untreated haemodialysis patients. This malabsorption of calcium could be corrected by the daily oral administration of 1--2 microgram of 1alphaOHD3 and 1--1.5 microgram of 1,25(OH)2D3. 5 microgram ...

journal_title：Nephron

authors： Pierides AM,Aljama P,Kerr DN,Scott M,Norman AW

更新日期：1978-01-01 00:00:00

abstract：:To avoid the use of aluminium as a phosphate binder, patients on CAPD who were stable were dialysed against a peritoneal dialysis fluid which was magnesium free. A mixture of calcium and magnesium carbonate was used as a phosphate binder over a period in excess of 1 year. Vitamin D analogues were used in the majority....

journal_title：Nephron

authors： Parsons V,Baldwin D,Moniz C,Marsden J,Ball E,Rifkin I

更新日期：1993-01-01 00:00:00

abstract：:The effects of dietary protein both before and after uranyl-nitrate-induced acute renal failure were investigated. Male Sprague-Dawley rats were maintained on high-protein (60%), normal-protein (20%), low-protein (5%) and no-protein diets for 8 days prior to intravenous administration of uranyl nitrate (10 mg/kg). Imm...

journal_title：Nephron

authors： Andrews PM,Bates SB

更新日期：1987-01-01 00:00:00

abstract：:The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group...

journal_title：Nephron

authors： Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

更新日期：1992-01-01 00:00:00

abstract：:Conglomerates of food and mucus or phytobezoars composed of vegetable matter are sometimes found in the stomach in the general population. Reports of phytobezoars in uremic patients are, however, scarce. Here we describe 2 uremic patients in which esophagogastroduodenoscopy was performed due to dyspepsia associated wi...

journal_title：Nephron

authors： Catalano C,Leone L,Fabbian F,Conz PA

更新日期：2002-03-01 00:00:00

abstract：:The effects of acute beta 2-type adrenoreceptor activation with intravenous albuterol on plasma and urinary sodium, potassium, calcium, magnesium, phosphate and lithium were investigated in 9 volunteers during acute hydration. When compared with the control infusion with inactive vehicle, beta 2-type adrenoreceptor ac...

journal_title：Nephron

authors： Duss G,Bianchetti MG,Cattaneo FA,Mullis PE,Krämer R,Peheim E,Oetliker OH

更新日期：1993-01-01 00:00:00