Abstract:
:The aim of this study was to assess the psychosocial effects of exercise training on hemodialysis (HD) patients. Thirty-one uremic patients, aged 50.6+/-11.6 years, on maintenance HD were studied. Twenty patients were selected at random for a 6-month exercise renal rehabilitation program (ERRP) consisting of 3 weekly sessions of exercise training. The other 11 patients were assigned to sedentary control status. A formal psychosocial assessment, which included affective (Beck Depression Inventory, BDI), quality of life (Quality of Life Index, QLI) and personality (Eysenck Personality Questionnaire, EPQ) parameters, was performed with validated questionnaires at the beginning and the end of the ERRP. After training significant improvement occurred in physical capacity (VO2max increased from 16.8+/-6.2 to 23.2+/-7.6 ml/kg/min, p < 0.05). Although the level of depression did not differ betwen the 2 groups at pretesting, the ERRP group showed a decrease in their self-report of depression (decrease in BDI score value, from 21.0+/-10.4 to 13.7+/-9.5, p < 0.05) after the training program. From the relationship between the baseline levels of BDI depression and changes in VO2max in the ERRP group it was suggested that the most severely depressed patients got the greatest beneficial effects from exercise training. Moreover, trained patients demonstrated an improvement in QLI (from 6.3+/-1.5 to 9.0+/-0.9, p < 0.05). This improvement was found to be dependent on the participation in ERRP, the effects of the training and the improvement in the depression. All the above functional and psychosocial parameters remained unchanged in the controls. The results demonstrate that ERRP is an effective emotional therapeutic method for HD patients and improves their quality of life.
journal_name
Nephronjournal_title
Nephronauthors
Kouidi E,Iacovides A,Iordanidis P,Vassiliou S,Deligiannis A,Ierodiakonou C,Tourkantonis Adoi
10.1159/000190266subject
Has Abstractpub_date
1997-01-01 00:00:00pages
152-8issue
2eissn
1660-8151issn
2235-3186journal_volume
77pub_type
临床试验,杂志文章,随机对照试验相关文献
NEPHRON文献大全abstract:INTRODUCTION:Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) reduce proteinuria and slow renal disease progression more effectively than other therapies in patients with chronic kidney disease (CKD). However, differences regarding efficacy and safety between these therapies rem...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000500925
更新日期:2019-01-01 00:00:00
abstract::A 57-year-old man with renal cell carcinoma associated with membranous glomerulonephropathy (MGN) developed a transient amelioration of the nephrotic syndrome after excision of the tumor. We tried to identify a nephritogenic tumor antigen using the immunoblotting technique in this patient with MGN, since previous stud...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000049047
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this is not known. One clue might lie with pattern recognition receptors (PRRs), which are triggers of ischemic i...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000456016
更新日期:2017-01-01 00:00:00
abstract::The effect of water immersion to the neck on renal calcium and magnesium handling was studied in 11 nephrotic patients. There was an increase in the urinary excretion of both calcium and magnesium on immersion, and a return towards preimmersion control values in the hour following immersion. Clearances of calcium and ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182897
更新日期:1983-01-01 00:00:00
abstract::In normal subjects, the gastric ionisation of calcium and phosphate seems to be a prerequisite for their intestinal absorption. We investigated the behavior of the plasma calcium and phosphate profile in 30 patients on regular dialysis treatment in the 6 h following a meal containing 1 g of calcium and 2 g of phosphat...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000064290
更新日期:2002-07-01 00:00:00
abstract::We present a 57-year-old man with end-stage renal failure due to chronic glomerulonephritis, who had been on hemodialysis for 13.5 years and had suffered from recurrent painful swelling of the left leg for 4.7 years. A diagnosis of deep venous thrombosis was made by the phlebography. Coagulation studies showed decreas...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187835
更新日期:1994-01-01 00:00:00
abstract::Cardiovascular disease is the major complication and cause of mortality in the dialysis population, accounting for about 40% of deaths. Oxidative stress has been strongly implicated in the pathogenesis of these events. As patients in end-stage renal disease (ESRD) are in a state of elevated free radical activity, the ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000065438
更新日期:2002-12-01 00:00:00
abstract::We found a strain of nonobese, nondiabetic (NON) mice which has spontaneous lipid deposition in glomerular capillary lumina. This strain was developed together with a diabetic strain of nonobese diabetic (NOD) mice for the generation of mouse models of diabetes mellitus. In the NON strain, contrary to the name, impair...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186417
更新日期:1991-01-01 00:00:00
abstract::A critical survey of the literature suggests that elevated serum uric acid is definitely associated with hypertension and may function as an independent risk factor in the development of this disease. The possible role of an elevated serum uric acid as an independent risk factor for the development of ischemic heart d...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181660
更新日期:1979-01-01 00:00:00
abstract::Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186831
更新日期:1992-01-01 00:00:00
abstract::Secondary hyperparathyroidism is common in chronic renal failure and is due to inadequate synthesis of calcitriol, the active metabolite of vitamin D. Intravenous administration of alphacalcidol, a synthetic analogue which is metabolized to calcitriol, was given during 12 weeks to 51 patients on chronic hemodialysis i...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186004
更新日期:1990-01-01 00:00:00
abstract::It has been assumed, but not documented, that hypercalcemia induces an appreciable reduction in the serum anion gap (AG) because it represents an increase in the level of unmeasured cations. To test this question, we retrospectively compared the data of 59 hypercalcemic patients with malignancy [group 1, serum Ca 13.3...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185946
更新日期:1990-01-01 00:00:00
abstract::Copper (Cu) and zinc (Zn) were measured in urine, serum and tissues from rats with nephrotic syndrome (NS) induced with a single subcutaneous dose of puromycin aminonucleoside (PAN; 15 mg/100 g BW). Control animals were pair-fed. Urine was collected daily, and the rats were sacrificed on day 10. PAN-nephrotic rats had...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187772
更新日期:1994-01-01 00:00:00
abstract::There is already a considerable amount of evidence suggesting that fibronectin (Fn) plays an important role in the pathogenic process in some forms of glomerulonephritis (GN). It has been postulated that Fn may participate in the progression or regression of glomerular diseases. The Fn is presented in the kidney as a ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187249
更新日期:1993-01-01 00:00:00
abstract::Platelet activation is commonly monitored with a battery of monoclonal antibodies against different platelet epitopes with controversial results. The transient expression of platelet markers and their role mediating interactions with other cells could easily explain these discrepancies. The present study has evaluated...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045167
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. METHODS:We performed an observational study on patients (≥18 years old) who had been on HD for ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000509350
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND/AIMS:Tolvaptan, a vasopressin V2 receptor antagonist, promotes the excretion of electrolyte-free water. Patients with heart failure or liver cirrhosis, whose urine osmolarity is high due to increased vasopressin, show a good response to tolvaptan; however, it remains dubious whether tolvaptan is also effecti...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000381859
更新日期:2015-01-01 00:00:00
abstract::A long-term hemodialysis male patient was known to have systemic iron overload due to regular blood transfusions. As he was suspected to have aluminum overload, he received a single intravenous administration of desferrioxamine (that supported the hypothesis). Four days later, he became highly febrile with no focus of...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185208
更新日期:1988-01-01 00:00:00
abstract::A 41-year-old woman was admitted to the hospital because of renal failure requiring hemodialysis treatment. Renal biopsy revealed active chronic interstitial nephritis. Renal function nearly normalized after removal of a copper-containing intrauterine device (IUCD). We conclude that copper-IUCDs may lead to renal fail...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186847
更新日期:1992-01-01 00:00:00
abstract::Circumstantial evidence that pIgA has a key role in glomerular injury of IgAN is now strong. Although the answers to the questions posed in this review are necessarily incomplete, they do indicate that (1) pIgA is a major component of mesangial IgA. (2) circulating pIgA is increased and this pIgA is particularly enhan...
journal_title:Nephron
pub_type: 社论
doi:10.1159/000187509
更新日期:1993-01-01 00:00:00
abstract::A 62-year-old woman gave clinical manifestation of liver cirrhosis. Urinary protein was false positive, no uremia was found and renal changes were entirely overlooked. Deposition of abundant lipids (globoside and ceramide trihexoside) was found in the kidneys; essentially degenerative changes of the tubular epithelia ...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000180480
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. METHODS:A home hemodialysis program was started in November 1998 in the University of Torino, Italy (2...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000063319
更新日期:2002-10-01 00:00:00
abstract::The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183053
更新日期:1983-01-01 00:00:00
abstract::Mizoribine has been shown to possess an immunosuppressive action that inhibits the proliferation of lymphocytes selectively by interfering with inosine monophosphate dehydrogenase. Recent studies have demonstrated that mizoribine improves renal tubulointerstitial fibrosis in the rat model of unilateral ureteral obstru...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000046065
更新日期:2001-10-01 00:00:00
abstract::Most hypertensive subjects are overweight, and as a consequence have an increased prevalence of hypercholesterolaemia, impaired glucose tolerance, and left ventricular hypertrophy. Reduction of the blood pressure by antihypertensive drugs without control of the obesity leaves these additional risk factors for cardiova...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184543
更新日期:1987-01-01 00:00:00
abstract::In an effort to elucidate immunopathogenic of membranous nephropathy (MN), freshly collected sera from patients with biopsy proven MN were assayed of circulating immune complexes (ICs) by the Raji cell method and for anti-renal tubular epithelial (RTE) antibodies by a newly established radioimmunoassay (RIA) and by in...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181675
更新日期:1979-01-01 00:00:00
abstract::Conglomerates of food and mucus or phytobezoars composed of vegetable matter are sometimes found in the stomach in the general population. Reports of phytobezoars in uremic patients are, however, scarce. Here we describe 2 uremic patients in which esophagogastroduodenoscopy was performed due to dyspepsia associated wi...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000049075
更新日期:2002-03-01 00:00:00
abstract::The purpose of the study was to investigate the effects of parathyroid hormone (PTH) infusion on antioxidant enzyme activity and lipid peroxidation of erythrocytes in five-sixths nephrectomized (Nx) rats. Five-sixths Nx rats had a higher osmotic fragility in red blood cells (RBC). Thyroparathyroidectomy (TPTX) effecti...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189046
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:The development of abnormalities in red blood cell (RBC) deformability in patients undergoing hemodialysis remains a major problem, because it is related to peripheral microcirculation, oxygen supply, and various complications in such patients. gamma-Linolenic acid (GLA; 18:3n-6), one of the polyunsaturated ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000045729
更新日期:2000-10-01 00:00:00
abstract::CBA/CaH-kdkd mice develop hereditary tubulointerstitial disease with mononuclear cell infiltration and cyst formation, possibly representing a model of human nephronophthisis. The purpose of the present investigation was to examine the components of the fibrotic changes which typically develop in the kidneys of these ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045191
更新日期:1998-11-01 00:00:00