Abstract:
:Calcitonin, whatever its origin, produces a decrease in the renal tubular reabsorption of sodium, phosphate and calcium in man and in the rat. Renal receptors for calcitonin have been demonstrated in the membranes of rat tubular cells using 125I salmon calcitonin as a tracer. Hormone-receptor interaction initiates the activation of membrane adenyl cyclase. In the rat and in man, the kidney plays a major role in degradation of both human and salmon calcitonin. Plasma levels of immunoreactive calcitonin are high in chronic renal failure. The question of the physiological role of calcitonin on kidney function is still unsettled.
journal_name
Nephronjournal_title
Nephronauthors
Ardaillou Rdoi
10.1159/000180515subject
Has Abstractpub_date
1975-01-01 00:00:00pages
250-60issue
3-5eissn
1660-8151issn
2235-3186journal_volume
15pub_type
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