Abstract:
:We studied complexes composed of C1q and beta 2-microglobulin (C1q.beta 2M) or serum amyloid P-component (C1q.SAP) in the sera of 38 patients receiving hemodialysis (HD) and 20 healthy control subjects using an enzyme-linked immunoassay. We also compared complex levels in HD patients with and without symptoms of HD-associated amyloidosis (HA). Serum C1q-beta 2M levels were significantly higher in HD patients without HA than in healthy control subjects and significantly higher in HD patients with HA than in HD patients without HA. Serum C1q.SAP levels were significantly lower in patients with HA than in those without HA. These results suggest that C1q.beta 2M may contribute to HA.
journal_name
Nephronjournal_title
Nephronauthors
Hasegawa M,Kawashima S,Shikano M,Kojima K,Yanai T,Hassegawa H,Tomita M,Murakami K,Kawamura N,Katsumata Hdoi
10.1159/000188506subject
Has Abstractpub_date
1995-01-01 00:00:00pages
380-3issue
4eissn
1660-8151issn
2235-3186journal_volume
69pub_type
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