Bradykinin induces a calcium-store- dependent calcium influx in mouse mesangial cells.

abstract：:We describe a case, seemingly sporadic, in which ocular and acral malformations were associated with an interstitial nephropathy; we made a diagnosis of acro-renal-ocular syndrome. There was no stasis, reflux, or urinary tract infection in our patient. We believe that interstitial nephritis in acro-renal-ocular syndro...

journal_title：Nephron

authors： Boscutti G,Pizzolitto S,Montanaro D,Messa P,Messa M,Favazza A,Beltrami CA,Mioni G

更新日期：1994-01-01 00:00:00

abstract：:Nonspecific symptoms are common in dialysis patients but few methods are available to measure their severity and their response to alteration in dialysis therapy. To determine the clinical features and measure the severity of the most important symptoms in end-stage renal disease (ESRD) patients, 97 dialysis patients ...

journal_title：Nephron

authors： Parfrey PS,Vavasour HM,Henry S,Bullock M,Gault MH

更新日期：1988-01-01 00:00:00

abstract：:The purpose of this study was to identify and characterize humic compounds in Anticolana Valley (Fiuggi) water. The capacity of this class of compounds to mobilize metals from solid phases could have an important role in calculi solubilization. Humic compounds were isolated, purified and characterised by FTIR, 1H-NMR ...

journal_title：Nephron

authors： Calace N,D'Ascenzo G,De Angelis Curtis S,Delfini M,Fraioli A,Petronio BM

更新日期：1999-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The prevalence of subclinical atherosclerosis and the main predictors of progression of this condition in patients undergoing peritoneal dialysis (PD) have been insufficiently investigated. OBJECTIVES AND METHOD:Following a prospective, multicenter, observational design, we studied 237 patients who were tre...

journal_title：Nephron

authors： Pérez Fontán M,Borràs Sans M,Bajo Rubio MA,Rodriguez-Carmona A,Betriu A,Valdivielso JM,Fernández E,NEFRONA Study investigators.

更新日期：2017-01-01 00:00:00

abstract：:Previous studies of IgA nephropathy have demonstrated a number of prognostically significant clinical and pathological factors in groups of patients with the full histological spectrum of the disease. Whether these factors can be applied to a group of IgA nephropathy patients with disease of moderate degree is unknown...

journal_title：Nephron

authors： Magil AB,Ballon HS

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIM:The impact of dialysis membrane permeability on neutrophil transmigration properties in vitro was examined in the present study. This issue has not been fully scrutinized before. METHODS:We studied the capacity of neutrophils collected from a group of dialysis patients randomly treated with cuprophan, l...

journal_title：Nephron

authors： Moshfegh A,Jacobson SH,Halldén G,Thylén P,Lundahl J

更新日期：2002-08-01 00:00:00

abstract：:The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...

journal_title：Nephron

authors： Zachée P,Daelemans R,Pollaris P,Boogaerts MA,Lins RL

更新日期：1994-01-01 00:00:00

abstract：:Deproteinized plasma from patients with renal failure had an inhibitory effect on Na,K ATPase activity measured in vitro by a linked-enzyme assay. No inhibitory effect was observed with plasma from normal subjects or from patients undergoing chronic ambulatory peritoneal dialysis. The inhibition of Na,K ATPase whether...

journal_title：Nephron

authors： Stokes GS,Norris LA,Marwood JF,Johnston H,Caterson RJ

更新日期：1990-01-01 00:00:00

abstract：:The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

journal_title：Nephron

authors： Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

更新日期：1991-01-01 00:00:00

abstract：:We studied the effects of oral furosemide, 80 mg/day for 7 days, on the response of urinary excretion of phosphate and cyclic AMP to exogenous parathyroid extract (PTE) in 6 normal subjects. All 6 subjects had marked increases in urinary calcium and a significant increase in urinary cyclic AMP from the control to the ...

journal_title：Nephron

authors： Fujita T,Delea CS,Bartter FC

更新日期：1985-01-01 00:00:00

abstract：:Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...

journal_title：Nephron

authors： Lobo PI,Okusa MD

更新日期：2019-01-01 00:00:00

abstract：:The decreases in serum osmolality as well as the rate of ultrafiltration during hemodialysis and the influence of each upon the side effects of this treatment were studied in 13 chronic stable dialysis patients. Mannitol (9 mosm/kg water) was infused in two out of four dialyses, in a double blind fashion. A solution o...

journal_title：Nephron

authors： Rosa AA,Shideman J,McHugh R,Duncan D,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiac surgery-associated severe acute kidney injury (SAKI) is associated with high mortality and poor quality of life. A prognostic score for SAKI may enable prevention of complications. METHODS:This observational study of 2,552 patients undergoing cardiac surgery from January 2006 to December 2011 i...

journal_title：Nephron

authors： Che M,Wang X,Liu S,Xie B,Xue S,Yan Y,Zhu M,Lu R,Qian J,Ni Z,Zhang W,Wang B

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Scientists use preclinical models of acute kidney injury (AKI) to decipher mechanisms and develop therapy, but translation of therapies to patients remains poor. Models that better resemble patients, including those within clinical care, should be considered. SUMMARY:Mice provide many advantages to the stud...

journal_title：Nephron

authors： Billings FT 4th

更新日期：2019-01-01 00:00:00

abstract：:The biochemistry and function of vanadate and its possible role in health as well as in disease remains one of the most fascinating stories in biology. This review has surveyed the pertinent literature regarding its effect in the normal kidney and other tissues. While inhibition of the Na(+)-K+ ATPase enzyme was the f...

journal_title：Nephron

authors： Dafnis E,Sabatini S

更新日期：1994-01-01 00:00:00

abstract：:Isolated hindquarters of bilaterally nephrectomized and sham-operated rats were perfused in the presence and absence of 14C-labelled serine, respectively. After a perfusion period of 30 min 14C-serine was 4,074 +/- 270 dpm/ml in the perfusion medium of sham-operated animals and decreased to 2,800 +/- 190 dpm/ml in the...

journal_title：Nephron

authors： Djovkar A,Hörl WH,Heidland A

更新日期：1983-01-01 00:00:00

abstract：AIM:Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. METHODS:We performed immunohistochemical staining using anti-SV40 ...

journal_title：Nephron

authors： Masutani K,Matsukuma Y,Tsuchimoto A,Okabe Y,Doi A,Kaku K,Nakamura M,Nakano T,Tsuruya K,Kitazono T

更新日期：2020-01-01 00:00:00

abstract：:We analyzed 10 patients (male:female 9:1, mean age 64.2 years) who developed hepatocellular carcinoma during the observation period of 2 years among 2,164 chronic hemodialysis patients in 23 dialysis centers. Among them, 409 patients were positive for serum anti-HCV antibodies (19%). They were all positive for serum a...

journal_title：Nephron

authors： Sakai Y,Izumi N,Tazawa J,Uchihara M,Akiba T,Marumo F,Sato C

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. METHODS:A home hemodialysis program was started in November 1998 in the University of Torino, Italy (2...

journal_title：Nephron

authors： Piccoli GB,Bermond F,Mezza E,Quaglia M,Pacitti A,Jeantet A,Segoloni GP

更新日期：2002-10-01 00:00:00

abstract：:In 25 patients with nephrotic syndromes of different origin, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion. This effect of indomethacin on GFR and proteinuria was more pronounced when the renin-angiotensin system was stimulated by a low-sodium diet and 50 m...

journal_title：Nephron

authors： Donker AJ,Brentjens JR,van der Hem GK,Arisz L

更新日期：1978-01-01 00:00:00

abstract：:Plasma immunoreactive atrial natriuretic factor (ANF) levels, their chromatographic profiles (high-performance liquid chromatography; HPLC) and changes during sequential ultrafiltration (UF; 1 litre/h) and biochemical correction without fluid removal (BC; 3 h) were studied in 8 end-stage chronic renal failure patients...

journal_title：Nephron

authors： Tonolo G,McMillan M,Richards AM,Montorsi P,Polonia J,Soro A,Troffa C,Glorioso N

更新日期：1990-01-01 00:00:00

abstract：:In the present study, activity of polymorphonuclear leukocyte (PMNL) intracellular antioxidant enzymes, i.e. catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX), was assessed in CRF patients on hemodialysis (HD), or continuous ambulatory peritoneal dialysis (CAPD) and in healthy controls. The activit...

journal_title：Nephron

authors： Shurtz-Swirski R,Mashiach E,Kristal B,Shkolnik T,Shasha SM

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND/AIM:Our previous study with prevalent cases suggested that some genetic, immunological and lifestyle-related factors increased the risk of immunoglobulin A nephropathy (IgAN). To confirm this hypothesis, we conducted another case-control study. METHODS:The study included 116 incident cases and 276 sex-, age...

journal_title：Nephron

authors： Wakai K,Nakai S,Matsuo S,Kawamura T,Hotta N,Maeda K,Ohno Y,Research Group on IgA Nephropathy.

更新日期：2002-01-01 00:00:00

abstract：:The glomerular mesangium is an important site of activity in patients with heroin addiction. We studied the effect of morphine, a metabolite of heroin, on the mesangial immunoglobulin G aggregate uptake in a model of specific mesangial cell injury. Isolated specific mesangial cell injury was developed in Lewis rats by...

journal_title：Nephron

authors： Singhal PC,Pan CQ,Sagar S,Valderrama E,Stahl RA

更新日期：1996-01-01 00:00:00

abstract：:Experiences with peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) program at a single center over 8 years were reviewed. Home-acquired peritonitis rates have been less than 1 episode per patient year since 1982. Gram-positive organisms continue to account for most episodes in a similar proportion. Act...

journal_title：Nephron

authors： Prowant B,Nolph K,Ryan L,Twardowski Z,Khanna R

更新日期：1986-01-01 00:00:00

abstract：:We report a case of graft intolerance syndrome in which transplant nephrectomy was performed 11 years after kidney transplantation. A 46-year-old man was admitted to our hospital in February 2018 with a mild fever, left lower abdominal pain, and gross hematuria with enlargement of the transplanted kidney. Urinary trac...

journal_title：Nephron

authors： Tomonari M,Kobayashi A,Yamamoto I,Hatanaka S,Kawabe M,Yamakawa T,Katsumata H,Katsuma A,Mafune A,Nakada Y,Koike Y,Miki J,Kimura T,Tanno Y,Yamamoto H,Yokoo T

更新日期：2020-01-01 00:00:00

abstract：:The decarboxylation and transamination reactions of glyoxylate, which divert this precursor from oxalate formation, have been investigated. Decarboxylation of glyoxylate is synergistic with 2-oxoglutarate and catalysed by 2-oxoglutarate:glyoxylate carboligase which co-chromatographs with the 2-oxoglutarate dehydrogena...

journal_title：Nephron

authors： Bais R,Rofe AM,Conyers RA

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Cyst infection is one of the complications of autosomal dominant polycystic kidney disease and polycystic liver disease. The diagnosis is typically made on a mix of clinical, laboratory and imaging abnormalities but the importance of individual items is uncertain. We aimed to perform a Delphi survey amongst ...

journal_title：Nephron

authors： Lantinga MA,Darding AJ,de Sévaux RG,Alam A,Bleeker-Rovers CP,Bobot M,Cornec-Le Gall E,Gevers TJ,Hassoun Z,Meijer E,Mrug M,Nevens F,Onuchic LF,Pei Y,Piccoli GB,Pirson Y,Rangan GK,Torra R,Visser FW,Jouret F,Kanaan N

更新日期：2016-01-01 00:00:00