Sustained-release bezafibrate corrects lipid abnormalities in patients on continuous ambulatory peritoneal dialysis.

abstract：:8 patients with thrombotic microangiopathy were treated with a new antithrombotic agent, defibrotide. This drug displays considerable fibrinolytic and antithrombotic activity, and induces generation and release of a prostacyclin-like substance from vascular tissue. At admission all patients presented severe renal invo...

journal_title：Nephron

authors： Bonomini V,Frascà GM,Raimondi C,Liviano D'arcangelo G,Vangelista A

更新日期：1985-01-01 00:00:00

abstract：:Nephrotic range proteinuria occurred in a 60-year-old woman with renal artery stenosis and marked hyperreninemia. Treatment by nephrectomy produced resolution of both proteinuria and hypertension. The gradual resolution of the proteinuria postoperatively suggested the proteinuria, at least in part, came from the contr...

journal_title：Nephron

authors： Eiser AR,Katz SM,Swartz C

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND/AIMS:Increased susceptibility of the kidney to acute renal failure (ARF) in the setting of sepsis even in the absence of systemic hypotension is well known. In the hypothesis that the proinflammatory cytokines and lipopolysaccharide (LPS) in gram-negative sepsis can directly cause renal tubular cell apoptosi...

journal_title：Nephron

authors： Jo SK,Cha DR,Cho WY,Kim HK,Chang KH,Yun SY,Won NH

更新日期：2002-07-01 00:00:00

abstract：:Sickle cell nephropathy characterized by proteinuria and predominantly glomerular lesions has not been studied as extensively as renal tubular alterations in sickle cell disease. We reviewed our experience with this entity over a 14-year period. Of 13 children with either proteinuria or the nephrotic syndrome, 8 showe...

journal_title：Nephron

authors： Tejani A,Phadke K,Adamson O,Nicastri A,Chen CK,Sen D

更新日期：1985-01-01 00:00:00

abstract：:Oral phosphatidylcholine at 900 mg/day was given to 4 patients with high lymph absorption for 8 weeks. Fluid and solute transfer before and after treatment were compared to 4 similar controls given placebo. None of the patients had overt ultrafiltration problems. After treatment, overnight peritoneal effluent phosphol...

journal_title：Nephron

authors： Chan PC,Tam SC,Robinson JD,Yu L,Ip MS,Chan CY,Cheng IK

更新日期：1991-01-01 00:00:00

abstract：:The urinary transforming growth factor beta (TGF-beta) excretion was measured in 33 patients including 10 with systemic lupus erythematosus (SLE), 8 with focal glomerular sclerosis (FGS), 9 with IgA nephropathy (IgAN), and 6 with membranous nephropathy (MN), and in 7 healthy subjects by enzyme-linked immunosorbent ass...

journal_title：Nephron

authors： Kanai H,Mitsuhashi H,Ono K,Yano S,Naruse T

更新日期：1994-01-01 00:00:00

abstract：:ExHC rats were bred from the Sprague-Dawley strain and are highly susceptible to dietary hypercholesterolemic stimuli. Although chemical and histological examination of the aorta from ExHC rats fed a diet containing 3% cholesterol, 0.6% sodium cholate and 15% olive oil (high-cholesterol diet, HCD) has been reported, r...

journal_title：Nephron

authors： Hattori M,Yamaguchi Y,Kawaguchi H,Ito K

更新日期：1993-01-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-...

journal_title：Nephron

authors： Elias AN,Vaziri ND,Pandian MR,Powers DR,Domurat E

更新日期：1988-01-01 00:00:00

abstract：:Recent efforts have standardized definitions and classification systems for acute kidney injury (AKI) and chronic kidney disease (CKD). These efforts have enhanced communication, recognition, and awareness of acute and CKDs and stimulated research on both disorders. However, abnormalities of kidney function and struct...

journal_title：Nephron

authors： Barry R,James MT

更新日期：2015-01-01 00:00:00

abstract：:29 patients receiving haemodialysis treatment for chronic renal failure were divided into two groups on the basis of the presence or absence of bone disease as defined by radiology and bone alkaline phosphatase. The group of patient with bone disease showed a significantly greater increase in protein-bound calcium dur...

journal_title：Nephron

authors： Gosling P,Naik RB,Price CP,Sammons HG,Robinson BH

更新日期：1979-01-01 00:00:00

abstract：:Effect of the immunosuppressive agent, ciclosporin (CS), on bovine serum albumin (BSA) nephritis in rats was evaluated. Eight weeks after immunization, 19 male Wistar rats received a daily intravenous dose of BSA (2 mg). Two weeks later, 11 rats received BSA and an oral dose of CS (10 mg/kg), and 8 rats received only ...

journal_title：Nephron

authors： Fujita M,Iida H,Asaka M,Izumino K,Takata M,Sasayama S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...

journal_title：Nephron

authors： Ghouti-Terki L,Chasseuil E,Rabot N,Paintaud G,François M,Birmelé B,Darrouzain F,Büchler M,Halimi JM,Ternant D

更新日期：2017-01-01 00:00:00

abstract：:The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...

journal_title：Nephron

authors： Goligorsky MS,Chaimovitz C,Rapoport J,Zevin L,Kiryati A,Lach S

更新日期：1983-01-01 00:00:00

abstract：:We investigated the best time of administration of desferrioxamine (DFO) with respect to the dialysis session, using the approach of the stochastic dynamic system, integrated with the classical pharmacokinetic models. In the 6 patients studied, the mean arrival times of DFO, aluminoxamine (AlO) and ferrioxamine (FO) w...

journal_title：Nephron

authors： Andriani M,Nordio M,Saporiti E

更新日期：1996-01-01 00:00:00

abstract：:The pharmacokinetics of procainamide in patients on continuous ambulatory peritoneal dialysis have been studied. A mean peak plasma concentration of 3.2 +/- 0.6 microgram/ml was achieved about 2 h after a single 500-mg oral procainamide hydrochloride dose. The procainamide elimination half-life ranged from 6.1 to 15.3...

journal_title：Nephron

authors： Raehl CL,Moorthy AV,Beirne GJ

更新日期：1986-01-01 00:00:00

abstract：:Isolated hindquarters of bilaterally nephrectomized and sham-operated rats were perfused in the presence and absence of 14C-labelled serine, respectively. After a perfusion period of 30 min 14C-serine was 4,074 +/- 270 dpm/ml in the perfusion medium of sham-operated animals and decreased to 2,800 +/- 190 dpm/ml in the...

journal_title：Nephron

authors： Djovkar A,Hörl WH,Heidland A

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The herbal medicine Sairei-to is efficacious in renal diseases where mesangial proliferation is a key event. We examined whether Sairei-to inhibits proliferation of cultured rat mesangial cells and investigated its mechanism of action. METHODS:The effect of Sairei-to on [(3)H]-thymidine incorporation stimul...

journal_title：Nephron

authors： Awazu M,Fujita H,Omori S,Hida M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the PTH-suppressive effect of intravenous calcitriol has already been demonstrated by various studies, the precise dose-response to calcitriol has not been fully determined for uremic secondary hyperparathyroidism (2HPT). In order to investigate in detail the dose-response of intravenous calcit...

journal_title：Nephron

authors： Koshikawa S,Akizawa T,Kurokawa K,Marumo F,Sakai O,Arakawa M,Morii H,Seino Y,Ogata E,Ohashi Y,Akiba T,Tsukamoto Y,Suzuki M

更新日期：2002-04-01 00:00:00

abstract：:Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...

journal_title：Nephron

authors： David-Walek T,Niederstadt C,Rob PM,Fricke L,Latta K,Steinhoff J,Stange EF

更新日期：2001-01-01 00:00:00

abstract：:Chromoblastomycosis is a rare, deep mycosis seen mostly in tropical and subtropical regions. We have encountered a kidney transplant recipient with this subcutaneous mycosis developing as an asymptomatic mass in the right forearm. The lesion recurred after an initial local excision, but it is now apparently cured 10 m...

journal_title：Nephron

authors： Morales LA,González ZA,Santiago-Delpín EA

更新日期：1985-01-01 00:00:00

abstract：:Chyloperitoneum is a rare condition in patients undergoing peritoneal dialysis. We report here a patient who developed chylous ascites during the course of tuberculous peritonitis. The diagnosis was confirmed by cultures of dialysate and peritoneal biopsy, and laparoscopy revealed severe hyperemia and intestine adhesi...

journal_title：Nephron

authors： Huang CH,Chen HS,Chen YM,Tsai TJ

更新日期：1996-01-01 00:00:00

abstract：:We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

journal_title：Nephron

authors： Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

更新日期：1985-01-01 00:00:00

abstract：:The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

journal_title：Nephron

authors： Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

更新日期：1991-01-01 00:00:00

abstract：:Diabetic nephropathy is the leading cause of kidney failure. Treatments with drugs that block the renin-angiotensin system have proven beneficial in slowing kidney disease progression among those with diabetes; their benefit is limited and they do not stop disease progression. Despite multiple clinical trials of vario...

journal_title：Nephron

authors： Toto RD

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...

journal_title：Nephron

authors： Covic AC,Sprague SM,Rastogi A,Ketteler M,Walpen S,Perrin A,Floege J

更新日期：2020-01-01 00:00:00

abstract：:We recently showed in dogs that there is a close relationship between bicarbonate reabsorption and glomerular filtration rate (GFR). The present studies were designed to confirm these findings in five normal men. Bicarbonate titrations were done after ingesting a low protein diet for one week and were repeated followi...

journal_title：Nephron

authors： Bennett CM,Falkinburg NR,Springberg PD

更新日期：1975-01-01 00:00:00

abstract：:It has been generally accepted that acidosis results in hyperkalemia because of shifts of potassium from the intracellular to the extracellular compartment. There is ample clinical and experimental evidence, however, to support the conclusion that uncomplicated organic acidemias do not produce hyperkalemia. In acidosi...

journal_title：Nephron

authors： Perez GO,Oster JR,Vaamonde CA

更新日期：1981-01-01 00:00:00

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:This study was conducted to test the hypothesis that the margin of safe fluoride exposure is narrowed in rats that are physiologically compromised by renal dysfunction. The study objective was to determine whether increases in fluoride retention and tissue fluoride levels in rats with surgically induced renal insuffic...

journal_title：Nephron

authors： Dunipace A,Brizendine E,Wilson M,Zhang W,Wilson C,Katz B,Kafrawy A,Stookey G

更新日期：1998-01-01 00:00:00