Abstract:
:We recently showed in dogs that there is a close relationship between bicarbonate reabsorption and glomerular filtration rate (GFR). The present studies were designed to confirm these findings in five normal men. Bicarbonate titrations were done after ingesting a low protein diet for one week and were repeated following elevation of GFR 11-29 per cent by high protein diet and dexamethazone ingestion. In every casetubular reabsorption of bicarbonate increased in proportion to the increases in GFR. We conclude that glomerular-tubular balance for bicarbonate reabsorption is a characteristic of human, as well as canine kidneys.
journal_name
Nephronjournal_title
Nephronauthors
Bennett CM,Falkinburg NR,Springberg PDdoi
10.1159/000180453subject
Has Abstractpub_date
1975-01-01 00:00:00pages
237-45issue
3-4eissn
1660-8151issn
2235-3186journal_volume
14pub_type
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