Proenkephalin: A New Biomarker for Glomerular Filtration Rate and Acute Kidney Injury.

abstract：:A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia in the lower extremities and elevated serum aminotransferase levels. His viral markers and other factors that may cause myal...

journal_title：Nephron

authors： Caglar K,Safali M,Yavuz I,Odabaşi Z,Yenicesu M,Vural A

更新日期：2002-12-01 00:00:00

abstract：:An autopsy case of membranous glomerulonephritis associated with enterococcal endocarditis was reported. Although enterococcal antigen was not identified in glomerular deposits, the eluate from the patient's renal tissue was shown to specifically recombine with cells of the enterococcus isolated from his own ante mort...

journal_title：Nephron

authors： Iida H,Mizumura Y,Uraoka T,Takata M,Sugimoto T,Miwa A,Yamagishi T

更新日期：1985-01-01 00:00:00

abstract：:The frequency of thrombocytopenia in patients with chronic renal failure (CRF) is controversial. This study was undertaken to investigate the platelet count in 55 patients with end-stage renal disease on maintenance hemodialysis and in 19 patients with CRF before hemodialysis had begun. In both groups platelet counts ...

journal_title：Nephron

authors： Gafter U,Bessler H,Malachi T,Zevin D,Djaldetti M,Levi J

更新日期：1987-01-01 00:00:00

abstract：:Radial arterial spasm in uremic patients undergoing construction of internal arteriovenous (AV) dialysis fistulas was investigated transcutaneously using ultrasonic Doppler flowmetry. In 5 of 15 patients, radial arterial blood flow was significantly decreased 5 min after anastomosing the radial cephalic vein with the ...

journal_title：Nephron

authors： Owada A,Saito H,Mochizuki T,Tanaka M,Otsuka M,Yokoyama Y,Fukuda S

更新日期：1993-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection has been associated with several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) were also described in several patients with overt AIDS. We describe a patient who presented with HUS and only subsequent investigation to find the caus...

journal_title：Nephron

authors： Badesha PS,Saklayen MG

更新日期：1996-01-01 00:00:00

abstract：:Recent efforts have standardized definitions and classification systems for acute kidney injury (AKI) and chronic kidney disease (CKD). These efforts have enhanced communication, recognition, and awareness of acute and CKDs and stimulated research on both disorders. However, abnormalities of kidney function and struct...

journal_title：Nephron

authors： Barry R,James MT

更新日期：2015-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:The authors utilized two groups of adult male rats to study the effect of chronic-uremic toxemia on the synthesis of thyroid hormones. The control group was sham operated, while the other group had about 70--80% of the left kidney tissue surgically excised and a total right nephrectomy performed 10 days later. At the ...

journal_title：Nephron

authors： Costa e Silva A,Albuquerque RH,Santana JP

更新日期：1978-01-01 00:00:00

abstract：:An animal model with experimental uremia is an important research tool for the study of the sequence of pathophysiological events taking place in the uremic syndrome. An appreciable number of animal models and methods for the induction of chronic uremia have been published. It is surprising that no such method has bee...

journal_title：Nephron

authors： Gabizon D,Goren E,Shaked U,Averbukh Z,Rosenmann E,Modai D

更新日期：1985-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：:In an attempt to clarify the renal involvement induced by human parvovirus B19 (HPB19) infection, we investigated 6 adult patients with transient urinary abnormalities followed by erythema infectiosum. All patients had HPB19-specific IgM antibody and showed mild proteinuria of 0.2-1.2 g/day with or without microscopic...

journal_title：Nephron

authors： Takeda S,Takaeda C,Takazakura E,Haratake J

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Anemia management in chronic hemodialysis (HD) has been affected by the implementation of the prospective payment system (PPS) and changes in clinical guidelines. These factors could impact red blood cell (RBC) transfusion in HD patients. Our distinctive care system contains complete records for all RBC tran...

journal_title：Nephron

authors： Albright RC Jr,Dillon JJ,Hocum CL,Stubbs JR,Johnson PM,Hickson LJ,Williams AW,Dingli D,McCarthy JT

更新日期：2016-01-01 00:00:00

abstract：:The diagnostic usefulness of bone marrow hemosiderin, serum ferritin, transferrin saturation, mean corpuscular volume (MCV) and red cell protoporphyrin (EPP) in the evaluation of iron status in patients on chronic hemodialysis was studied in 39 subjects. The correlation between serum ferritin and the number of transfu...

journal_title：Nephron

authors： Moreb J,Popovtzer MM,Friedlaender MM,Konijn AM,Hershko C

更新日期：1983-01-01 00:00:00

abstract：:An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, theref...

journal_title：Nephron

authors： Ehrenfeld M,Licht A,Stessman J,Yanko L,Rosenmann E

更新日期：1977-01-01 00:00:00

abstract：:The concentration changes, during hemodialysis treatment, of 18 characteristic uremia compounds, analyzed by high-pressure liquid chromatography in sera of renal patients were studied. Pre- to postdialysis concentration ratios (dialysis ratio, D) varied from 0.83 to 3.04 for the different solutes. A division into thre...

journal_title：Nephron

authors： Schoots AC,Peeters JA,Gerlag PG

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The introduction of automated biopsy devices and the localization of the kidney by ultrasound were aimed at optimizing efficacy and safety of the percutaneous renal biopsy procedure. We evaluated these technological advances in our renal biopsies performed in children. METHODS:We sequentially used the Silve...

journal_title：Nephron

authors： Feneberg R,Schaefer F,Zieger B,Waldherr R,Mehls O,Schärer K

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Progressive nephropathy is one of the main features of Fabry disease (FD). It has been supposed that an early phase, clinically silent disease occurs in childhood and adolescence and is characterized by glomerular hyperfiltration (HF). Surprisingly, although HF has been reported in several stu...

journal_title：Nephron

authors： Riccio E,Sabbatini M,Bruzzese D,Annicchiarico Petruzzelli L,Pellegrino A,Spinelli L,Esposito R,Imbriaco M,Feriozzi S,Pisani A,on behalf of AFFIINITY Group.

更新日期：2019-01-01 00:00:00

abstract：:A four-year-old male with steroid refractory nephrotic syndrome was found to have diffuse deposition of alpha 2-macroglobulin (alpha 2M) in the glomeruli which showed diffuse mesangial proliferation and partial hyalinization by light microscopy. Camostat mesylate, a commercially available synthetic proteinase inhibito...

journal_title：Nephron

authors： Asami T,Ohsawa S,Tomisawa S,Hashimoto K,Toyabe S,Sakai K

更新日期：1992-01-01 00:00:00

abstract：:Cerebral salt-wasting syndrome (CSWS) has been regarded as a misnomer of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). We take the position that CSWS does exist and might be more common than SIADH. Differentiation between groups has been difficult because of overlapping signs, symptoms, and ...

journal_title：Nephron

authors： Maesaka JK,Gupta S,Fishbane S

更新日期：1999-06-01 00:00:00

abstract：:We describe a case of nephrotic syndrome (idiopathic membranous glomerulonephropathy) with high serum HDL cholesterol (91 mg/100 ml) which increased to 240 mg/100 ml following steroid therapy. The increase in HDL was mainly a result of increased HDL2 and increased plasma apolipoprotein A-I. ...

journal_title：Nephron

authors： Sasaki J,Hara F,Motooka T,Naito S,Arakawa K

更新日期：1985-01-01 00:00:00

abstract：:Cytomegalovirus is the most important viral infection in kidney transplants, but rarely affects the allograft after the sixth month posttransplantation. We present a patient who developed renal failure eighteen months posttransplant; a kidney biopsy showed cytomegalovirus inclusions, acute tubular necrosis and mild in...

journal_title：Nephron

authors： Trimarchi H,Jordan R,Iotti A,Forrester M,Iotti R,Freixas E,Martínez J,Schropp J,Pereyra H,Efrón E

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this is not known. One clue might lie with pattern recognition receptors (PRRs), which are triggers of ischemic i...

journal_title：Nephron

authors： DeWolf SE,Shigeoka AA,Scheinok A,Kasimsetty SG,Welch AK,McKay DB

更新日期：2017-01-01 00:00:00

abstract：:We found a strain of nonobese, nondiabetic (NON) mice which has spontaneous lipid deposition in glomerular capillary lumina. This strain was developed together with a diabetic strain of nonobese diabetic (NOD) mice for the generation of mouse models of diabetes mellitus. In the NON strain, contrary to the name, impair...

journal_title：Nephron

authors： Watanabe Y,Itoh Y,Yoshida F,Koh N,Tamai H,Fukatsu A,Matsuo S,Hotta N,Sakamoto N

更新日期：1991-01-01 00:00:00

abstract：:The fall in white blood cells (WBC) and arterial oxygen pressure that occurs during hemodialysis was investigated as a function of different dialysis membranes and different sterilization methods. 8 chronic hemodialysis patients were studied and each was dialyzed with three different membranes: cellulosic hollow fiber...

journal_title：Nephron

authors： Hakim RM,Lowrie EG

更新日期：1982-01-01 00:00:00

abstract：:A previous study from our laboratory has shown that erythropoietin (EPO), beside its traditional role in erythropoiesis, acts as an alleviator of oxidative stress and inflammation in chronic hemodialysis (HD) patients, conferred in part by activated polymorphonuclear leukocytes (PMNLs). To substantiate this phenomenon...

journal_title：Nephron

authors： Sela S,Shurtz-Swirski R,Sharon R,Manaster J,Chezar J,Shkolnik G,Shapiro G,Shasha SM,Merchav S,Kristal B

更新日期：2001-07-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:Although serologic studies have identified hantaviral infection in the United States, acute disease has not been recognized. This study describes 3 cases of domestically acquired hemorrhagic fever with renal syndrome (HFRS) in the United States. Infection was due to a local strain of Seoul virus (Baltimore rat virus)....

journal_title：Nephron

authors： Glass GE,Watson AJ,LeDuc JW,Childs JE

更新日期：1994-01-01 00:00:00

abstract：:Peritonitis has proven to be the major deterrent to the further growth of continuous ambulatory peritoneal dialysis (CAPD) as a treatment strategy for end-stage renal disease. The correct treatment of peritonitis remains unsettled as evidenced by the presence of advocates for oral, intravenous or intraperitoneal antib...

journal_title：Nephron

authors： Harford AM,Sica DA,Tartaglione T,Polk RE,Dalton HP,Poynor W

更新日期：1986-01-01 00:00:00

abstract：:The daily urinary excretion of oxalate has been found to be lower than normal in patients with renal failure and the decrease to be directly proportional to the impairment of renal function. It has also been found that the gut flora from uremic patients destroys oxalate 'in vitro' more efficiently than the gut flora f...

journal_title：Nephron

authors： Camici M,Balestri PL,Lupetti S,Colizzi V,Falcone G

更新日期：1982-01-01 00:00:00

abstract：:Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

journal_title：Nephron

authors： Kirschbaum BB

更新日期：1976-01-01 00:00:00