Abstract:
BACKGROUND:Peritoneal dialysis (PD) is an ideal model for testing remote monitoring (RM). In this study, we evaluated the RM application longitudinally in stable patients undergoing automated PD (APD). METHODS:This was an observational study, comparing outcomes in patients with (current patients) and without (historical data) exposure of RM. We analyzed cost-effectiveness of RM-APD measuring the number of night alarms, number of hospital visits, direct and indirect costs. RESULTS:Changes in APD prescription were almost double in the case group (RM) compared to the control group (p = 0.0005). The need for in-person visits and nocturnal alarms was significantly less in RM-APD than in traditional APD (p = 0.01 and p = 0.002, respectively). The distance traveled by patients in the case of RM-APD was reduced by 1,134 km with a time saving of 1,554 min for patients. The overall cost reduction for the PD center in terms of time/nurse and time/physician was 2,647 and 3,673 min, respectively. All these advantages were obtained in the presence of an improved technique survival with a significant reduction of dropouts. All patients found that it is easy to use the RM system and were satisfied with the high level of interaction with the care team and with the possibility of timely resolving technical problems. CONCLUSION:These data confirm the long-term benefits of RM applied to APD. RM-APD is cost-effective; it allows early detection and resolution of problems, improved treatment compliance, reduction of patient's access to hospital center for technical and clinical complications with consequent savings, and improved patient's quality of life.
journal_name
Nephronjournal_title
Nephronauthors
Milan Manani S,Rosner MH,Virzì GM,Giuliani A,Berti S,Crepaldi C,Ronco Cdoi
10.1159/000496182subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1-9issue
1eissn
1660-8151issn
2235-3186pii
000496182journal_volume
142pub_type
杂志文章相关文献
NEPHRON文献大全abstract::Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000501639
更新日期:2019-01-01 00:00:00
abstract::HLA antigens of Japanese patients with primary glomerulopathies were determined, and the frequency of each HLA antigen was compared with that of Japanese normal controls. IgA nephropathy with HLA-DR4, idiopathic membraneous glomerulopathy with DR2, lipoid nephrosis with DRw53 and poststreptococcal glomerulonephritis w...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184089
更新日期:1987-01-01 00:00:00
abstract::In 88 patients with the nephrotic syndrome (NS) we estimated plasma volume (PV) with 131I-albumin (RISA) and calculated blood volume (BV) from PV and whole body hematocrit (Ht). To assess whether this method gives erroneously high values in the NS, the transcapillary escape rate of albumin (TER) and large vessel Ht/wh...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183302
更新日期:1984-01-01 00:00:00
abstract::In Wistar rats V-U reflux with distilled water and sterile saline of varying osmolar strength produces scars in the perihilar region of the kidneys in 80% of animals. Using Indian ink as a marker, rupture of the forniceal epithelium regularly followed V-U reflux. Intrapelvic pressure rose to 120 mm Hg during the reflu...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180706
更新日期:1976-01-01 00:00:00
abstract::A case of inferior vena caval compression by hepatic cysts as a complication of adult polycystic kidney disease is presented and its management is discussed. ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185816
更新日期:1990-01-01 00:00:00
abstract::A previously described method for recovering a proximal renal tubular epitheal antigen (HRTE-1) from normal human kidney was modified by using ion-exchange and immunoaffinity chromatography in order to create easily reproducible conditions for antigen isolation. Radioiodinated HRTE-1 was then used to establish a 3-hou...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181942
更新日期:1980-01-01 00:00:00
abstract::It has been reported that calcium deposition and calcium content in cultured human aortic smooth muscle cells (SMC) increased when the cells are incubated in a medium with a high phosphate concentration (2 mM). To determine the cellular components or soluble factors contributing to the deposition, we cultured commerci...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000065461
更新日期:2002-12-01 00:00:00
abstract::Gentamicin doses of 40 mg/kg body weight/day were administered intravenously to 62 Wistar rats. Nineteen animals were also treated orally with an NaHCO3 solution in place of water. The gentamicin-treated animals showed increased albuminuria immediately after the 3rd day of treatment. The fact that this increase was ma...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185043
更新日期:1988-01-01 00:00:00
abstract::Mysterious deaths of archeologists after opening Egyptian tombs have been suspected to be secondary to inhalation of mycotoxin, however, the hypothesis has never been verified. Recently, we observed a case of acute renal failure (ARF) undeniably due to inhalation of ochratoxin of Aspergillus ochraceus. After spending ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187411
更新日期:1993-01-01 00:00:00
abstract::Gastrointestinal infection with verotoxin-producing Escherichia coli (VTEC) has been strongly implicated in the etiology of the hemolytic uremic syndrome (HUS), the leading cause of pediatric acute renal failure. The binding of fluorescein-conjugated VT1 overlaid on to frozen human renal sections has been examined. Se...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187761
更新日期:1994-01-01 00:00:00
abstract::It has been assumed, but not documented, that hypercalcemia induces an appreciable reduction in the serum anion gap (AG) because it represents an increase in the level of unmeasured cations. To test this question, we retrospectively compared the data of 59 hypercalcemic patients with malignancy [group 1, serum Ca 13.3...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185946
更新日期:1990-01-01 00:00:00
abstract::A very simple analytical procedure with dimethylmethylene blue as photometric reagent was applied for the evaluation of glycosaminoglycan (GAG) urinary excretions and concentrations in both sexes, calcium oxalate stone formers, and a control group. The GAG concentrations varied significantly in stone formers (males an...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188306
更新日期:1994-01-01 00:00:00
abstract::We reviewed the recommendations and outcomes for all patients with diabetes mellitus and end-stage renal disease referred to the Medical Center Hospital of Vermont from 1971 through December 1983. During this period, we recommended transplantation in 53 of 73 patients evaluated. Thirty-two transplants were performed i...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183693
更新日期:1986-01-01 00:00:00
abstract::Clearance techniques were used to evaluate renal tubular sodium and water excretion in 4 patients with antibiotic-induced acute renal failure (ARF). Creatinine clearances and maximal urine flow rates of patients with ARF (22.6 and 5.23 ml/min, respectively) were significantly lower than control values during hypotonic...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181226
更新日期:1978-01-01 00:00:00
abstract::The capacity of peripheral blood mononuclear cells (PBMC) to undergo spontaneous and induced interleukin-1 (IL-1) production was examined in 10 healthy controls and in 10 patients undergoing intermittent hemodialysis (HD) using cuprophane membranes. Extracellular and cytoplasmic IL-1 activity was assayed by biologic a...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185187
更新日期:1988-01-01 00:00:00
abstract::We report a case of visceral leishmaniasis in a 38-year-old renal transplant recipient living in an endemic country. Antimonial derivatives induced a rapid remission. A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases. We suggest that the specific immunosuppressi...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000186779
更新日期:1992-01-01 00:00:00
abstract::We investigated the best time of administration of desferrioxamine (DFO) with respect to the dialysis session, using the approach of the stochastic dynamic system, integrated with the classical pharmacokinetic models. In the 6 patients studied, the mean arrival times of DFO, aluminoxamine (AlO) and ferrioxamine (FO) w...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188845
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Haemophilus influenzae infection is a mild and self-limited disease in the healthy population. However, it may show an aggressive course in the immunocompromised state which underlines the importance of vaccination against this agent. On the other hand, posttranplant immunosuppression may impair immune respo...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000045246
更新日期:1999-01-01 00:00:00
abstract::Renal handling of urate, xanthine and hypoxanthine was studied in a hypouricemic patient who had increased plasma concentrations of xanthine and hypoxanthine. The patient, a 50-year-old man, had been suffering from Parkinson's disease, while neither systemic disorders nor particular renal diseases known to affect plas...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186961
更新日期:1992-01-01 00:00:00
abstract::In the present study the influence of a mixture of keto analogues/amino acids (KA) on PTH levels in 18 RDT patients was examined. Ten of them were treated with KA over a period of 3 months, while the other 8 patients served as control group. The KA-treated patients showed a significant fall in PTH and plasma phosphate...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183804
更新日期:1986-01-01 00:00:00
abstract::Because of the great problem of viral hepatitis in hemodialysis patients, the Italian Society of Nephrology decided to perform a national epidemiologic survey. We contacted 467 nephrological centers by a questionnaire which let us have information on 25,746 uremic patients: 18,338 on HD, 2,250 on PD and 5,176 with kid...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186905
更新日期:1992-01-01 00:00:00
abstract::A 37-year-old female presented with acute onset of glomerulonephritis 10 days following an upper respiratory infection. Serum complement components were depressed and proteinuria exceeded 3.0 g daily. Renal biopsy revealed granular staining of IgG and C3 along the basement membrane as well as small amounts of IgA in a...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183980
更新日期:1986-01-01 00:00:00
abstract::The cytoprotective effect of ulinastatin was studied in LLC-PK1 cells treated with antimycin A, gentamicin, or cisplatin. All of the three agents induced a concentration-dependent increase in the release of lactate dehydrogenase and a decrease in the amount of remaining protein. In the cell injury models treated with ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000190195
更新日期:1997-01-01 00:00:00
abstract::A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000186805
更新日期:1992-01-01 00:00:00
abstract::The effects of dietary protein both before and after uranyl-nitrate-induced acute renal failure were investigated. Male Sprague-Dawley rats were maintained on high-protein (60%), normal-protein (20%), low-protein (5%) and no-protein diets for 8 days prior to intravenous administration of uranyl nitrate (10 mg/kg). Imm...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184167
更新日期:1987-01-01 00:00:00
abstract::We present a rare case of IgA nephropathy in a patient who developed atypical hemolytic uremic syndrome (aHUS) associated with a complement factor H (CFH) gene mutation, and who was successfully treated with eculizmab. A 76-year-old man was admitted as the patients had thrombotic microangiopathies findings. The patien...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000485194
更新日期:2018-01-01 00:00:00
abstract::We present data on the costs and impact of chronic renal failure, the primary renal diseases leading to end-stage renal disease in children, and review the adaptive responses and the pathophysiology and complications of uremia in experimental animals and in man. A treatment strategy is summarized. ...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000045157
更新日期:1998-10-01 00:00:00
abstract::To determine the cytokines responsible for the increase in production of IgA in patients with IgA nephropathy (IgAN), the roles of interleukin-4 (IL-4) and soluble CD23 (sCD23) were examined. Peripheral blood mononuclear cells (PBMCs) and serum were obtained from 24 patients with IgAN and 14 patients with non-IgA prol...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188805
更新日期:1996-01-01 00:00:00
abstract::The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183053
更新日期:1983-01-01 00:00:00
abstract::Blood eosinophils were counted by the counting-chamber method in 21 regular hemodialysis patients. Before dialysis, eosinophil counts were within the normal range in all patients (mean 98 cells/mm3, range 6-350). After the first 15 min of hemodialysis, with not reused coils or hollow-fiber dialysers, a significant dro...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182805
更新日期:1982-01-01 00:00:00