Increased clearance rate of prednisone in the isolated perfused liver of uremic rats.

abstract：BACKGROUND:Post-transplant diabetes mellitus (PTDM) is a frequent and severe complication after renal transplantation. In fact, PTDM is a risk factor for both infection and cardiovascular diseases. The prevalence and incidence of PTDM have a bimodal evolution: early (up to 3 months) and late PTDM (beyond 12 months). Th...

journal_title：Nephron

authors： Morales Febles R,Negrín Mena N,Rodríguez-Rodríguez AE,Díaz Martín L,González Rinne F,Marrero Miranda D,González Rinne A,Álvarez González A,Pérez Tamajón L,Acosta Sørensen C,Rodríguez Hernández A,Domínguez-Rodríguez A,García Baute

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：:The renal cortex of anesthetized dogs was found to contain per gram lyophilized dry weight 9.5+/-0.6 micronmol ATP, 3.2+/-0.5 MICRONMOL ADP, 0.68+/-0.3 MICRONMOL AMP, and 22.5+/-4.4 micronmol Pi. These amounts were unchanged by the administration of moderate amounts of saline or hypertonic mannitol in load doses of ab...

journal_title：Nephron

authors： Urbaitis BK,Blake WD

更新日期：1977-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection has been associated with several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) were also described in several patients with overt AIDS. We describe a patient who presented with HUS and only subsequent investigation to find the caus...

journal_title：Nephron

authors： Badesha PS,Saklayen MG

更新日期：1996-01-01 00:00:00

abstract：:Computerized tomography (CT) has the advantage of allowing the isolation of trabecular bone of the axial skeleton, which is the more sensitive to metabolic changes. By means of single-energy X-ray CT we have devised a method for assessing trabecular bone mass (TBM) at L-4 vertebral body, which has an acceptable reprod...

journal_title：Nephron

authors： Torres A,Lorenzo V,Gonzalez-Posada JM

更新日期：1986-01-01 00:00:00

abstract：:It is unknown whether continuous renal replacement techniques result in diminished morbidity and mortality when compared to conventional dialytic techniques. To investigate this issue a previously described, retrospectively studied group of critically ill patients with severe acute renal failure treated by conventiona...

journal_title：Nephron

authors： Bellomo R,Farmer M,Parkin G,Wright C,Boyce N

更新日期：1995-01-01 00:00:00

abstract：:While the bulk of renal hypertrophy induced by contralateral nephrectomy or a high-protein diet consists of tubular cell growth, there is some evidence suggesting that mesangial cells play a role in this phenomenon. Previous data suggest that this role of mesangial cells is associated with their proliferation. We, the...

journal_title：Nephron

authors： Weissgarten J,Modai D,Berman S,Cohn M,Galperin E,Averbukh Z

更新日期：2000-07-01 00:00:00

abstract：:Proteoglycans constitute a heterogenous group of complex macromolecules, consisting of a backbone core protein and a variable number of sulfated polysaccharide side chains covalently linked to the core. A dual function for these polyanionic glycosaminoglycans in kidney physiology has been proposed: to maintain a fixed...

journal_title：Nephron

authors： Pyke C,Kristensen P,Ostergaard PB,Oturai PS,Rømer J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the PTH-suppressive effect of intravenous calcitriol has already been demonstrated by various studies, the precise dose-response to calcitriol has not been fully determined for uremic secondary hyperparathyroidism (2HPT). In order to investigate in detail the dose-response of intravenous calcit...

journal_title：Nephron

authors： Koshikawa S,Akizawa T,Kurokawa K,Marumo F,Sakai O,Arakawa M,Morii H,Seino Y,Ogata E,Ohashi Y,Akiba T,Tsukamoto Y,Suzuki M

更新日期：2002-04-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：:The effects of acute beta 2-type adrenoreceptor activation with intravenous albuterol on plasma and urinary sodium, potassium, calcium, magnesium, phosphate and lithium were investigated in 9 volunteers during acute hydration. When compared with the control infusion with inactive vehicle, beta 2-type adrenoreceptor ac...

journal_title：Nephron

authors： Duss G,Bianchetti MG,Cattaneo FA,Mullis PE,Krämer R,Peheim E,Oetliker OH

更新日期：1993-01-01 00:00:00

abstract：:Cardiovascular complications seriously affect posttransplant survival in patients after successful renal transplantation. Abnormalities in blood rheology may contribute to these complications. Therefore, we studied the blood rheology before and during a 1-year observation period after grafting in 9 patients by serial ...

journal_title：Nephron

authors： Koppensteiner R,Derfler K,Ehringer H

更新日期：1996-01-01 00:00:00

abstract：:Micropuncture studies were performed in intact and thyroparathyroidectomized (TPTX) dogs to evaluate the relationship between the absolute level of serum ultrafilterable phosphate concentration (SUFP) and proximal bicarbonate reabsorption. In both groups of animals, a reverse linear relationship was noted between the ...

journal_title：Nephron

authors： Puschett JB,Fernandez PC

更新日期：1977-01-01 00:00:00

abstract：:To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

journal_title：Nephron

authors： Duan SB,Wu HW,Luo JA,Liu FY

更新日期：1999-01-01 00:00:00

abstract：:The effect of isotonic mannitol and saline in the early phase of mercuric chloride-(HgCl2-)induced acute renal failure (ARF) in the dog was evaluated. During the first 3 h after HgCl2 alone, glomerular filtration rate (GFR) fell from 1.94 +/- 0.14 to 1.04 +/- 0.11 and renal blood flow (RBF) from 13.99 +/- 1.18 to 7.28...

journal_title：Nephron

authors： Vanholder R,Leusen I,Lameire N

更新日期：1984-01-01 00:00:00

abstract：:A long-term hemodialysis male patient was known to have systemic iron overload due to regular blood transfusions. As he was suspected to have aluminum overload, he received a single intravenous administration of desferrioxamine (that supported the hypothesis). Four days later, he became highly febrile with no focus of...

journal_title：Nephron

authors： Hoen B,Renoult E,Jonon B,Kessler M

更新日期：1988-01-01 00:00:00

abstract：:To determine whether the chelation of aluminium enhances the haemopoietic response to recombinant human erythropoietin (r-HuEPO), desferrioxamine (DFO) at a dose of 20-30 mg/kg was given to 7 of 17 transfusion-dependent haemodialysis patients treated with r-HuEPO (40 units/kg/dialysis i.v.). The two randomly allocated...

journal_title：Nephron

authors： Roger SD,Stewart JH,Harris DC

更新日期：1991-01-01 00:00:00

abstract：:CBA/CaH-kdkd mice develop hereditary tubulointerstitial disease with mononuclear cell infiltration and cyst formation, possibly representing a model of human nephronophthisis. The purpose of the present investigation was to examine the components of the fibrotic changes which typically develop in the kidneys of these ...

journal_title：Nephron

authors： Sibalic V,Sun L,Sibalic A,Oertli B,Ritthaler T,Wüthrich RP

更新日期：1998-11-01 00:00:00

abstract：:3-Deoxyglucosone (3-DG) has been identified as an intermediate of the Maillard reaction in vitro. We measured serum 3-DG levels using gas chromatography/mass spectrometry and found a marked elevation in serum 3-DG levels in uremic patients compared with healthy subjects. The uremic patients with diabetes showed signif...

journal_title：Nephron

authors： Niwa T,Takeda N,Miyazaki T,Yoshizumi H,Tatematsu A,Maeda K,Ohara M,Tomiyama S,Niimura K

更新日期：1995-01-01 00:00:00

abstract：:Hypertension secondary to renal transplantation was studied in our experimental model in the rat. In this model an intravenous injection of donor strain blood into recipients of allogeneic donor kidneys prior to transplantation was used to prolong the allograft survival. A reduced renal function associated with the hy...

journal_title：Nephron

authors： de Keijzer MH,Provoost AP,van Aken M,Kort WJ,Wolff ED,Molenaar JC

更新日期：1985-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Renal dyslipoproteinemia is characterized by the accumulation of intact and partially metabolized triglyceride-rich lipoproteins. Reduced lipolytic enzyme activities may be one of the major pathophysiological mechanisms contributing to a retarded catabolism of these lipoproteins in patients with renal insuff...

journal_title：Nephron

authors： Samuelsson O,Attman PO,Knight-Gibson C,Kron B,Larsson R,Mulec H,Weiss L,Alaupovic P

更新日期：1997-01-01 00:00:00

abstract：:The effect of ischemia on renal blood flow (RBF) in the rat has been an unsettled question. This study used a totally extractable indicator, radioactive microspheres, with a reference arterial sample, to study RBF quantitatively 10 and 60 min after 1 h of unilateral renal artery clamping in anesthetized, heparinized r...

journal_title：Nephron

authors： Riley AL

更新日期：1978-01-01 00:00:00

abstract：:It has been generally accepted that acidosis results in hyperkalemia because of shifts of potassium from the intracellular to the extracellular compartment. There is ample clinical and experimental evidence, however, to support the conclusion that uncomplicated organic acidemias do not produce hyperkalemia. In acidosi...

journal_title：Nephron

authors： Perez GO,Oster JR,Vaamonde CA

更新日期：1981-01-01 00:00:00

abstract：:Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

journal_title：Nephron

authors： Kirschbaum BB

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:A high prevalence of cardiovascular diseases (CVDs) and infections in patients with chronic kidney disease (CKD) arises partly due to a high inflammatory state and aberrations in immune cells function. Following in vitro stimulation of leukocytes with different T-cell mitogens, we observed a lower level of i...

journal_title：Nephron

authors： Mansouri L,Nopp A,Jacobson SH,Hylander B,Lundahl J

更新日期：2017-01-01 00:00:00

abstract：:Bone mineral content (BMC) was measured at the lumbar spine region by means of dual photon absorptiometry over a 3-year period in 20 patients on regular hemodialysis (RHD). Baseline mean BMC at the start of the monitoring was significantly decreased to 82.64% of predicted value (p less than 0.05). During a 3-year foll...

journal_title：Nephron

authors： Eeckhout E,Verbeelen D,Sennesael J,Kaufman L,Jonckheer MH

更新日期：1989-01-01 00:00:00

abstract：:A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia in the lower extremities and elevated serum aminotransferase levels. His viral markers and other factors that may cause myal...

journal_title：Nephron

authors： Caglar K,Safali M,Yavuz I,Odabaşi Z,Yenicesu M,Vural A

更新日期：2002-12-01 00:00:00

abstract：:1 day after bilateral ureteral occlusion (BUO), the extracellular fluid (ECF) volume of rats was increased by 2.8 ml/100 g body weight above those values observed after either a sham operation or after 1 day of unilateral ureteral occlusion (UUO). The plasma urea concentration of BUO rats averaged about five times the...

journal_title：Nephron

authors： Sophasan S,Sorrasuchart S

更新日期：1984-01-01 00:00:00

abstract：:Serum prolactin levels were elevated in male Sprague-Dawley rats with acute renal failure induced by glycerol administration. Specific prolactin binding to kidney membrane preparations was reduced in glycerol and antirat glomerular basement membrane serum-treated rats, after morphological and biochemical acute renal f...

journal_title：Nephron

authors： Dobbie JW,Mountjoy K,Cowden EA,Allison ME,Ratcliffe JG

更新日期：1981-01-01 00:00:00