Characteristics of the peritoneal mass transfer of parathormone in patients under continuous ambulatory peritoneal dialysis therapy.

Abstract:

:Recent studies have shown that the mass transfer coefficients (MTC) for low- and middle-molecular-weight substances are maintained at medium terms in patients under continuous ambulatory peritoneal dialysis (CAPD) therapy. We have studied the MTC for parathormone (MW 5,500-6,000) in 29 patients under CAPD. 11 patients were assessed once, 9 patients were assessed twice, and 9 were assessed three times, with 6-month intervals between assessments; in 15 cases nitroprusside (4.5 mg/l) was added to the dialysate, and in 2 cases the assessment was carried out during an episode of peritonitis. A bicompartmental model with exponential ultrafiltration was used, and the generation rates were calculated by mass balance. The MTC was calculated by minimization of the quadratic error, following the procedure of Runge and Kutta. The mean MTC values were 21.2 +/- 5.9 for urea, 10.26 +/- 5.9 for creatinine 2.8 +/- 1.8 for inulin and 1.0 +/- 0.8 for parathormone (PTH), with significant correlation between the MTC values for PTH and inulin (r = 0.5, p less than 0.01). There is a direct correlation between MTCPTH and peritoneal PTH clearance, and an inverse one between MTCPTH and serum PTH, with r = 0.8 and 0.51, respectively. No correlation was found between the MTC for inulin or PTH and the duration of the CAPD therapy, nor with the number of episodes of peritonitis. No significant medium-term variations were detected in the MTC values for PTH and inulin. Both peritonitis and the intraperitoneal administration of nitroprusside induce significant increases in the MTCPTH.

journal_name

Nephron

journal_title

Nephron

authors

Rodríguez-Carmona A,Selgas R,Martínez ME,Ortí F,Miguel JL,Salinas M,Riñón C,Sánchez-Sicilia L

doi

10.1159/000183201

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

21-4

issue

1

eissn

1660-8151

issn

2235-3186

journal_volume

37

pub_type

杂志文章

相关文献

NEPHRON文献大全
  • Antiglomerular basement membrane antibody-mediated glomerulonephritis after intranasal cocaine use.

    abstract::We report a case of rapidly progressive glomerulonephritis due to antiglomerular basement membrane (anti-GBM) antibodies that progressed to end-stage renal disease in a 35-year-old man who used intranasal cocaine on an occasional basis. In contrast to many prior reports of acute renal failure occurring with cocaine-as...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045328

    authors: Peces R,Navascués RA,Baltar J,Seco M,Alvarez J

    更新日期:1999-01-01 00:00:00

  • The determination of plasma transferrin receptor as good index of erythropoietic activity in renal anemia and after renal transplantation.

    abstract::Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000188938

    authors: de Paoli Vitali E,Ricci G,Perini L,Malacarne F,Vedovato M,Guerra G,Dapporto M,Gilli P

    更新日期:1996-01-01 00:00:00

  • Copper and zinc metabolism in aminonucleoside-induced nephrotic syndrome.

    abstract::Copper (Cu) and zinc (Zn) were measured in urine, serum and tissues from rats with nephrotic syndrome (NS) induced with a single subcutaneous dose of puromycin aminonucleoside (PAN; 15 mg/100 g BW). Control animals were pair-fed. Urine was collected daily, and the rats were sacrificed on day 10. PAN-nephrotic rats had...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187772

    authors: Pedraza-Chaverrí J,Torres-Rodríguez GA,Cruz C,Mainero A,Tapia E,Ibarra-Rubio ME,Silencio JL

    更新日期:1994-01-01 00:00:00

  • Hyperosmolality, High Blood Pressure, and Decreased Estimated Glomerular Filtration Rate in US Adolescents, National Health and Nutrition Examination Survey 1999-2012.

    abstract:BACKGROUND:Experimental evidence suggests that hyperosmolality may be a causative factor in the development of both salt-sensitive hypertension and chronic kidney disease (CKD). There are no population-wide studies in young persons to assess the relationships among these factors. OBJECTIVE:To determine the association...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000497780

    authors: Chmielewski J,Khalsa DD,Carmody JB

    更新日期:2019-01-01 00:00:00

  • Factors influencing the intestinal absorption of calcium and phosphorus following renal transplantation.

    abstract::After successful renal transplantation there is continuing malabsorption of calcium and phosphorus. This is due in part to impaired glomerular filtration rate, and in part to the action of steroid on calcium and phosphorus absorption. The effect of steroids is most marked over the first 18 months after transplantation...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181989

    authors: Walker GS,Peacock M,Marshall DH,Giles GR,Davison AM

    更新日期:1980-01-01 00:00:00

  • Immune response to Haemophilus influenzae type B vaccination in renal transplant recipients with well-functioning allografts.

    abstract:BACKGROUND:Haemophilus influenzae infection is a mild and self-limited disease in the healthy population. However, it may show an aggressive course in the immunocompromised state which underlines the importance of vaccination against this agent. On the other hand, posttranplant immunosuppression may impair immune respo...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000045246

    authors: Sever MS,Yildiz A,Eraksoy H,Badur S,Yüksel-Onel D,Görçin B,Türk S,Erkoç R

    更新日期:1999-01-01 00:00:00

  • Radial artery pseudoaneurysm complicating a Brescia-Cimino dialysis fistula.

    abstract::The authors describe an unusual case of radial artery pseudoaneurysm in a patient with a Brescia-Cimino fistula. Evaluation of a pulsatile mass on the patient's forearm which occurred after hemodialysis led to a nondiagnostic fistulogram. Color flow ultrasound was helpful in identifying the nature of the abnormality, ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000188958

    authors: Labus TP,Trerotola SO,Savader SJ

    更新日期:1996-01-01 00:00:00

  • Effects on renal function of a low-nitrogen diet supplemented with essential amino acids and ketoanalogues and of hemodialysis and free protein supply in patients with chronic renal failure.

    abstract::Creatinine clearance has been repeatedly measured in three groups of chronic uremics. In the first control group (31 cases), following a conventional low-protein diet, creatinine clearance declined linearly with time. In the second group (12 cases), following very low nitrogen diet supplemented with essential amino ac...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182036

    authors: Barsotti G,Guiducci A,Ciardella F,Giovannetti S

    更新日期:1981-01-01 00:00:00

  • Bradykinin induces a calcium-store- dependent calcium influx in mouse mesangial cells.

    abstract::Bradykinin (BK) elicits extracellular-dependent [Ca2+](i) elevations in mouse mesangial cells (MMC) that are not blocked by verapamil, nifedipine, L-nicardipine, NiCl(2), or LaCl(3). The aim of the present study was to evaluate the mechanisms involved in calcium influx induced by BK in MMC. [Ca2+](i) was analyzed thro...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000058409

    authors: Campos AH,Calixto JB,Schor N

    更新日期:2002-06-01 00:00:00

  • Assessment of renal function in the early stages of nephrotoxicity induced by iodinated contrast media.

    abstract::To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000045488

    authors: Duan SB,Wu HW,Luo JA,Liu FY

    更新日期:1999-01-01 00:00:00

  • Renal accumulation of glycosphingolipids. Report of a case and a review of literature.

    abstract::A 62-year-old woman gave clinical manifestation of liver cirrhosis. Urinary protein was false positive, no uremia was found and renal changes were entirely overlooked. Deposition of abundant lipids (globoside and ceramide trihexoside) was found in the kidneys; essentially degenerative changes of the tubular epithelia ...

    journal_title:Nephron

    pub_type: 杂志文章,评审

    doi:10.1159/000180480

    authors: Miyasaki K

    更新日期:1975-01-01 00:00:00

  • Effect of a new antithrombotic agent (defibrotide) in acute renal failure due to thrombotic microangiopathy.

    abstract::8 patients with thrombotic microangiopathy were treated with a new antithrombotic agent, defibrotide. This drug displays considerable fibrinolytic and antithrombotic activity, and induces generation and release of a prostacyclin-like substance from vascular tissue. At admission all patients presented severe renal invo...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000190340

    authors: Bonomini V,Frascà GM,Raimondi C,Liviano D'arcangelo G,Vangelista A

    更新日期:1985-01-01 00:00:00

  • Characteristics of Patients Who Achieve Serum Phosphorus Control on Sucroferric Oxyhydroxide or Sevelamer Carbonate: A post hoc Analysis of a Phase 3 Study.

    abstract:INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000507258

    authors: Covic AC,Sprague SM,Rastogi A,Ketteler M,Walpen S,Perrin A,Floege J

    更新日期:2020-01-01 00:00:00

  • Effect of gemfibrozil on lipoprotein abnormalities in chronic renal insufficiency: a controlled study in human chronic renal disease.

    abstract:BACKGROUND:Renal dyslipoproteinemia is characterized by the accumulation of intact and partially metabolized triglyceride-rich lipoproteins. Reduced lipolytic enzyme activities may be one of the major pathophysiological mechanisms contributing to a retarded catabolism of these lipoproteins in patients with renal insuff...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000189551

    authors: Samuelsson O,Attman PO,Knight-Gibson C,Kron B,Larsson R,Mulec H,Weiss L,Alaupovic P

    更新日期:1997-01-01 00:00:00

  • Evaluation of the proteolytic activity of factor D accumulated as an active serine protease in patients with chronic renal failure.

    abstract::Complement factor D, a complement system serine protease, circulating in vivo as its active form, accumulates in patients with chronic renal failure. The pathophysiological role of this active protease in these patients was examined by studies on activities of excess factor D on 10 synthetic peptide substrates for som...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187824

    authors: Inagi R,Miyata T,Oda O,Maeda K,Inoue K

    更新日期:1994-01-01 00:00:00

  • Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition.

    abstract::End-stage renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease (CKD). ESRD claims many lives every year. It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the future development of CKD and ESRD. While our understanding of the pathophysiolog...

    journal_title:Nephron

    pub_type: 杂志文章,评审

    doi:10.1159/000474960

    authors: Ó hAinmhire E,Humphreys BD

    更新日期:2017-01-01 00:00:00

  • Establishing the relationship between complement activation and stimulation of phagocyte oxidative metabolism in hemodialyzed patients: a randomized prospective study.

    abstract::The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000186565

    authors: Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

    更新日期:1991-01-01 00:00:00

  • Uremic acquired renal cystic disease. Natural history and complications.

    abstract::Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...

    journal_title:Nephron

    pub_type: 社论

    doi:10.1159/000186434

    authors: Ishikawa I

    更新日期:1991-01-01 00:00:00

  • Factors Influencing Cyst Infection in Autosomal Dominant Polycystic Kidney Disease.

    abstract:BACKGROUND:Cyst infection is a frequent and serious complication of autosomal dominant polycystic kidney disease (ADPKD) that is often difficult to treat. However, the factors influencing cyst infection are still unknown. Therefore, we investigated clinical factors related to the duration of hospitalization and death d...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000493806

    authors: Suwabe T,Ubara Y,Hayami N,Yamanouchi M,Hiramatsu R,Sumida K,Sawa N,Sekine A,Kawada M,Hasegawa E,Hoshino J,Takaichi K

    更新日期:2019-01-01 00:00:00

  • Proliferative glomerulonephritis in monoclonal gammopathy.

    abstract::A 62-year-old white male suffering from plasmacytosis with monoclonal gammopathy developed gastrointestinal bleeding, microscopic hematuria, proteinuria and progressive azotemia. A renal biopsy demonstrated capillary wall thickening, mesangial hyperplasia, crescent formation and subepithelial humps. Serum immunoglobul...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180902

    authors: Dhar SK,Smith EC,Fresco R

    更新日期:1977-01-01 00:00:00

  • Circulating anti-tubular basement membrane antibody in a variety of human renal diseases: detection and significance.

    abstract::Serum specimens from 99 selected renal patients were examined over a 3-year period by both a hemagglutination technique (HA) and an indirect immunofluorescent (IIF) method for the presence of circulating antibody against tubular basement membrane (TBM). 11 patients were found with anti-TBM antibodies. 6 of them also h...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181943

    authors: Cattran DC

    更新日期:1980-01-01 00:00:00

  • Platelet-leukocyte activation during hemodialysis detected with a monoclonal antibody to leukocyte integrin CD11b.

    abstract::Platelet activation is commonly monitored with a battery of monoclonal antibodies against different platelet epitopes with controversial results. The transient expression of platelet markers and their role mediating interactions with other cells could easily explain these discrepancies. The present study has evaluated...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045167

    authors: Hernández MR,Galán AM,Lozano M,Bozzo J,Cases A,Escolar G,Calls J,Ordinas A

    更新日期:1998-10-01 00:00:00

  • Characteristic cytokine products of Th1 and Th2 cells in hemodialysis patients.

    abstract::Dysfunction of the host defense against infection in hemodialysis (HD) patients has major clinical and socioeconomic implications. T helper type 1 (Th1) and type 2 (Th2) cytokines are implicated in regulating the immune responses and, therefore, may be involved in impaired status. The present study was designed to exa...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045516

    authors: Daichou Y,Kurashige S,Hashimoto S,Suzuki S

    更新日期:1999-01-01 00:00:00

  • Reduced collagenolytic activity of rat kidneys with steptozotocin diabetes.

    abstract::Collagenolytic activity of rat kidneys with streptozotocin diabetes was estimated by means of a biological collagenase assay and compared to healthy controls. Collagenolytic activity was found significantly decreased in rat kidneys with diabetes correlating with blood glucose levels (r = -0.82, p less than 0.001). Ele...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182517

    authors: Lubec G,Leban J,Peyroux J,Sternberg M,Pollak A,Latzka U,Coradello H

    更新日期:1982-01-01 00:00:00

  • Kidney disease and silicosis.

    abstract:AIM:To determine the prevalence of kidney disease in a cohort of individuals with silicosis. METHODS:Review of medical records and questionnaires from patients reported to a state surveillance system for silicosis. Reporting of individuals with silicosis is required by state law. All individuals with silicosis reporte...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045624

    authors: Rosenman KD,Moore-Fuller M,Reilly MJ

    更新日期:2000-05-01 00:00:00

  • Anuric renal failure precipitated by indomethacin and triamterene.

    abstract::We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000183461

    authors: Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

    更新日期:1985-01-01 00:00:00

  • Cellular component of vascular calcification. Fibroblasts are essential for calcium deposition in cultured cells.

    abstract::It has been reported that calcium deposition and calcium content in cultured human aortic smooth muscle cells (SMC) increased when the cells are incubated in a medium with a high phosphate concentration (2 mM). To determine the cellular components or soluble factors contributing to the deposition, we cultured commerci...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000065461

    authors: Watanabe Y,Suzuki M,Oyama Y,Kusano E,Tamba K,Iimura O,Ito C,Imai M,Asano Y

    更新日期:2002-12-01 00:00:00

  • Severe tubulopathy and kidney graft rupture after coadministration of mannitol and ciclosporin.

    abstract::Spontaneous allograft rupture after kidney transplantation is a rare complication usually due to an acute rejection of the interstitial type. In a 32-year-old man kidney transplantation was performed under immunosuppression with prednisolone and ciclosporin (CS). The dose of CS was 5 mg/kg body weight intravenously fo...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187003

    authors: Biesenbach G,Zazgornik J,Kaiser W,Grafinger P,Stuby U,Gross C,Hartl P,Brücke P

    更新日期:1992-01-01 00:00:00

  • Continuous venovenous haemodialysis: a three-pump system.

    abstract::A simple three-pump-based system for the performance of continuous venovenous haemodialysis is described. The method employs access to the circulation via a double-lumen catheter, and by means of a standard extracorporeal peristaltic pump the blood is circulated through a haemofiltration filter. Standard solutions for...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000188835

    authors: Møller Jensen D,Bistrup C,Pedersen RS

    更新日期:1996-01-01 00:00:00

  • Regional characterization of G-protein subunits in glomeruli, cortices and medullas of the rat kidney.

    abstract::We examined the types of guanine nucleotide-binding regulatory (G) protein subunits in isolated glomeruli, cortices excluding glomeruli and medullas of rat kidneys using bacterial toxin-catalyzed adenosine 5'-diphosphate (ADP) ribosylation and specific immunoblots. ADP ribosylation catalyzed by cholera or pertussis to...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187862

    authors: Yanagisawa H,Kurihara N,Klahr S,Morrissey J,Wada O

    更新日期:1994-01-01 00:00:00