Effects of ursodeoxycholic acid on photodynamic therapy in a murine tumor model.

abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

journal_title：Photochemistry and photobiology

authors： Sirangelo I,Irace G,Bismuto E

更新日期：1994-06-01 00:00:00

abstract：:Pyrimidine dimers were measured in epidermal DNA of SKH:HR1 mice following exposure to solar-simulated UV radiation (SSUV, 290-400 nm) or to UVA (320-400 nm). Mice were exposed to SSUV or UVA after topical application (2 mg/cm2) of vehicle, a UVB absorber (5% 2-ethylhexyl p-methoxycinnamate [2-EHMC]), or a broad-spect...

journal_title：Photochemistry and photobiology

authors： Ley RD,Fourtanier A

更新日期：1997-06-01 00:00:00

abstract：:A widely published expression for dipole strengths of optical transitions is found to require correction. The proposed adjustment, which involves the refractive index of the solvent in which the strengths are measured, may lead to significant changes in predictions that have been based on the equation. We discuss a cl...

journal_title：Photochemistry and photobiology

authors： Knox RS

更新日期：2003-05-01 00:00:00

abstract：:Continuous red light controls starch degradation in turions of Spirodela polyrhiza [Dölger, K., U. K. Tirlapur and K.-J. Appenroth [1997] Photochem. Photobiol. 66, 126-127 (1997)]. This light could be replaced by repeated red light pulses with the reciprocity law fulfilled over a large range of fluence rates. The effe...

journal_title：Photochemistry and photobiology

authors： Appenroth KJ,Gabrys H

更新日期：2001-01-01 00:00:00

abstract：:A spectral resolution procedure was used to resolve the absorption, excitation and emission spectra of the fluorescein monoanion in a number of solvent-water mixtures. This permitted an analysis of the effect of the solvent environment on the spectral properties of the monoanion and on the lactone/monoanion/dianion tr...

journal_title：Photochemistry and photobiology

authors： Klonis N,Sawyer WH

更新日期：2000-08-01 00:00:00

abstract：:In current clinical practice, photodynamic therapy (PDT) is carried out with prescribed drug doses and light doses as well as fixed drug-light intervals and illumination fluence rates. This approach can result in undesirable treatment outcomes of either overtreatment or undertreatment because of biological variations ...

journal_title：Photochemistry and photobiology

authors： Zeng H,Korbelik M,McLean DI,MacAulay C,Lui H

更新日期：2002-04-01 00:00:00

abstract：:Tetraarylporphyrins substituted with nitro groups at beta-pyrrolic positions are potential candidates for electron-accepting pigments in model systems for photosynthesis. The photophysics of 2-nitro-5,10,15,20-tetra-p-tolylporphyrin and its zinc analog have been studied in order to evaluate this potential. The ground ...

journal_title：Photochemistry and photobiology

authors： Gust D,Moore TA,Luttrull DK,Seely GR,Bittersmann E,Bensasson RV,Rougée M,Land EJ,De Schryver FC,Van der Auweraer M

更新日期：1990-04-01 00:00:00

abstract：:Light-dark cycles are considered important cues to entrain biological clocks. A feedback loop of clock gene transcription and translation is the molecular basis underlying the mechanism of both central and peripheral clocks. Xenopus laevis embryonic melanophores respond to light with melanin granule dispersion, respon...

journal_title：Photochemistry and photobiology

authors： Magalhães Moraes MN,de Oliveira Poletini M,Ribeiro Ramos BC,de Lima LH,de Lauro Castrucci AM

更新日期：2014-05-01 00:00:00

abstract：:In this study, water-soaked seeds of sunflower were exposed to He-Ne laser irradiation of different energies to determine whether or not He-Ne laser irradiation caused changes to seed thermodynamic and germination parameters as well as effects on the activities of germination enzymes. The experiment comprised four ene...

journal_title：Photochemistry and photobiology

authors： Perveen R,Ali Q,Ashraf M,Al-Qurainy F,Jamil Y,Raza Ahmad M

更新日期：2010-09-01 00:00:00

abstract：:Cationic polythiophenes have been shown to be potent antimicrobial compounds due to their ability to absorb visible light and sensitize the production of reactive oxygen species (ROS) as well as their ability to selectively associate with and damage negatively charged cell envelopes. This study demonstrates the abilit...

journal_title：Photochemistry and photobiology

authors： Brown DM,Yang J,Strach EW,Khalil MI,Whitten DG

更新日期：2018-11-01 00:00:00

abstract：:It has previously been demonstrated that chronic low-dose solar-simulated UV radiation could induce both local and systemic immunosuppression as well as tolerance to a topically applied hapten. In this study, we have used a chronic low-dose UV-irradiation protocol to investigate the effects of UVA on the skin immune s...

journal_title：Photochemistry and photobiology

authors： Bestak R,Halliday GM

更新日期：1996-12-01 00:00:00

abstract：:Photodynamic therapy (PDT) using the second-generation photosensitizer phthalocyanine (Pc) 4 causes mitochondrial damage and induces apoptosis through the release of cytochrome c to the cytosol. Another protein of the mitochondrial intermembrane space, Smac/DIABLO (second mitochondria-derived activator of caspase/dire...

journal_title：Photochemistry and photobiology

authors： Usuda J,Chiu SM,Azizuddin K,Xue LY,Lam M,Nieminen AL,Oleinick NL

更新日期：2002-08-01 00:00:00

abstract：:The UVA and UVB components of sunlight can produce three classes of bipyrimidine DNA photolesions [cyclobutane pyrimidine dimers (CPDs), pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) and related Dewar valence isomers (DewarPPs)]. The UVA/UVB ratio of sunlight is high in winter and low in summer in the Northern He...

journal_title：Photochemistry and photobiology

authors： Nishimura K,Ikehata H,Douki T,Cadet J,Sugiura S,Mori T

更新日期：2020-12-03 00:00:00

abstract：:In the present study, photodynamic activity of a novel photosensitizer (PS), Chlorin e(6)-2.5 N-methyl-d-glucamine (BLC 1010), was evaluated using the chorioallantoic membrane (CAM) as an in vivo model. After intravenous (i.v.) injection of BLC 1010 into the CAM vasculature, the applicability of this drug for photodyn...

journal_title：Photochemistry and photobiology

authors： Pegaz B,Debefve E,Borle F,Ballini JP,Wagnières G,Spaniol S,Albrecht V,Scheglmann D,Nifantiev NE,van den Bergh H,Konan YN

更新日期：2005-11-01 00:00:00

abstract：:Exposure of cultured MRC5 human fibroblasts or NCTC 2544 human keratinocytes to mild doses of ultraviolet A (UVA: 320-400 nm) radiations markedly decreased the actin reactivity with fluorescein-labeled phalloidin. This indicates a change in the degree of polymerization of actin and thus in the organization of actin fi...

journal_title：Photochemistry and photobiology

authors： Djavaheri-Mergny M,Pieraggi MT,Mazière C,Santus R,Lageron A,Salvayre R,Dubertret L,Mazière JC

更新日期：1994-01-01 00:00:00

abstract：:Photoautotrophic growth of Chlamydomonas reinhardtii was shown to be independent of the presence of atmospheric oxygen. Under constant light and photoautotrophic conditions, C. reinhardtii grew equally well in either air or 367 PPM CO2-in-He. During 12-h light-dark cycles, the cells in air grew substantially faster th...

journal_title：Photochemistry and photobiology

authors： Graves DA,Spradlin GM,Greenbaum E

更新日期：1990-09-01 00:00:00

abstract：:In this manuscript, we demonstrate the control of film thickness and surface wettability in the photochemical immobilization of poly (vinyl alcohol) (PVA) to a self-assembled monolayer (SAM) containing a phthalimide chromophore. Surface attachment is characterized by ellipsometry and contact angle measurements. The we...

journal_title：Photochemistry and photobiology

authors： Carroll GT,Turro NJ,Mammana A,Koberstein JT

更新日期：2017-10-01 00:00:00

abstract：:Leaf discs, enclosed in a photoacoustic (PA) chamber, generate two types of PA gas-uptake signals under certain conditions. Type I is manifested by a severe signal decrease that develops slowly under very low-light intensity and often reaches negative values. It is partially reversed by low-intensity far-red light. Ty...

journal_title：Photochemistry and photobiology

authors： Malkin S,Havaux M

更新日期：2001-10-01 00:00:00

abstract：:Exploration of environmental dynamics using intrinsic biological probe tryptophan is very important; however, it suffers from various difficulties. An alternative probe, kynurenine (KN), has been found to be an efficient probe for the ultrafast dynamics in the biological environment (Goswami et al., [2010] J. Phys. Ch...

journal_title：Photochemistry and photobiology

authors： Rakshit S,Goswami N,Pal SK

更新日期：2012-01-01 00:00:00

abstract：:Antibodies and antigen binding fragments thereof were photochemically immobilized on surface-modified silicon chips of 5 x 5 mm size. Silicon surface-grafted diazirines and benzophenones formed covalent bonds with the immunoreagents on light activation. Photolithographic immobilization of monoclonal antibodies in aque...

journal_title：Photochemistry and photobiology

authors： Sundarababu G,Gao H,Sigrist H

更新日期：1995-06-01 00:00:00

abstract：:Various photosensitizers were grafted by conventional peptide coupling methods to functionalized silica with several macroscopic shapes (powders, films) or embedded in highly transparent and microporous silica xerogel monoliths. Owing to the transparency and free-standing shape of the monoliths, the transient species ...

journal_title：Photochemistry and photobiology

authors： Ronzani F,Saint-Cricq P,Arzoumanian E,Pigot T,Blanc S,Oelgemöller M,Oliveros E,Richard C,Lacombe S

更新日期：2014-03-01 00:00:00

abstract：:Photolysis of 6-chloro-1,3-dimethyluracil and mesitylene in the presence of trifluoroacetic acid (TFA) at low temperature gave 1,3,5,7,9- and 1,3,6,8,10-pentamethylcyclooctapyrimidine-2,4-diones (1b, 1c). Sequential photoreaction of the former (1b) resulted in the formation of 9,11-diazapentacyclo[6.4.0.0(1,3).0(2,5)....

journal_title：Photochemistry and photobiology

authors： Ohkura K,Nishijima K,Seki K

更新日期：2001-09-01 00:00:00

abstract：:Polyenic systems are involved in light perception of numerous living organisms. Although a π-conjugated backbone is a common feature of all polyenes, their photophysics may vary. We provide a comparative quantum mechanical study of low-lying S1 and S2 excited states in short (3-5 double bonds) symmetric all-trans line...

journal_title：Photochemistry and photobiology

authors： Dokukina I,Marian CM,Weingart O

更新日期：2017-11-01 00:00:00

abstract：:Effects of solvent, pH and hydrogen bonding with N-methylimidazole (MIm) on the photophysical properties of 1-hydroxyfluorenone (1HOF) have been studied. Fluorescence lifetime, fluorescence quantum yield and triplet yield measurements demonstrated that intersystem crossing was the dominant process in apolar media and ...

journal_title：Photochemistry and photobiology

authors： Sebok-Nagy K,Biczók L,Morimoto A,Shimada T,Inoue H

更新日期：2004-07-01 00:00:00

abstract：:Photosensitized protein cross-linking has been recently developed to seal wounds and strengthen tissue. Although the photosensitizing dye, Rose Bengal (RB), is phototoxic to cultured cells, cytotoxicity does not accompany RB-photosensitized tissue repair in vivo. We investigated whether the environment surrounding cel...

journal_title：Photochemistry and photobiology

authors： Yao M,Gu C,Doyle FJ Jr,Zhu H,Redmond RW,Kochevar IE

更新日期：2014-03-01 00:00:00

abstract：:Photosensitizer (PS)-antibody conjugates (photoimmunoconjugates, PICs) enable cancer cell-targeted photodynamic therapy (PDT). Nonspecific chemical bioconjugation is widely used to synthesize PICs but gives rise to several shortcomings. The conjugates are heterogeneous, and the process is not easily reproducible. More...

journal_title：Photochemistry and photobiology

authors： Sadiki A,Kercher EM,Lu H,Lang RT,Spring BQ,Zhou ZS

更新日期：2020-05-01 00:00:00

abstract：:The neonatal immune environment and the events that occur during this time have profound effects for the adult period. While protective immune responses can develop, the neonatal immune system, particularly the skin immune system (SIS), tends to promote tolerance. With this information we undertook a number of studies...

journal_title：Photochemistry and photobiology

authors： Muller HK,Malley RC,McGee HM,Scott DK,Wozniak T,Woods GM

更新日期：2008-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

journal_title：Photochemistry and photobiology

authors： Weston MA,Patterson MS

更新日期：2011-09-01 00:00:00

abstract：:We developed a novel method for the isolation of the PSI-LHCI-LHCII complex from spinach leaves. The supercomplex was resolved into a core complex (CPI), LHCII trimers, LHCI dimers and LHCII monomers using green gel electrophoresis. We then investigate changes in the fluorescence and absorption spectra of PSI-LHCI-LHC...

journal_title：Photochemistry and photobiology

authors： Qin X,Wang W,Wang K,Xin Y,Kuang T

更新日期：2011-01-01 00:00:00

abstract：:Absorbance changes were monitored from 250 to 650 nm during the first microsecond after photolysis of detergent suspensions of bovine rhodopsin at 20 degrees C. Global analysis of the resulting data produced difference spectra for bathorhodopsin, BSI and lumirhodopsin which give the change in absorbance of the aromati...

journal_title：Photochemistry and photobiology

authors： Lewis JW,Jäger S,Kliger DS

更新日期：1997-12-01 00:00:00