Variability and genetic structure of the population of watermelon mosaic virus infecting melon in Spain.

abstract：:Previous studies have shown that a 558-bp fragment of human cytomegalovirus (CMV) DNA contained within pCM4127 and designated CMV mtr can morphologically transform rodents cells in vitro. By cotransformation with pCM4127 and a plasmid conferring G418 resistance, pSV2neo, morphologically transformed NIH3T3 cell lines w...

journal_title：Virology

authors： Buonaguro FM,McDougall JK,Galloway DA

更新日期：1987-01-01 00:00:00

abstract：:Expression of adenosine deaminase acting on RNA1 (ADAR1) is driven by alternative promoters. Promoter PA, activated by interferon (IFN), produces transcripts that encode the inducible p150 ADAR1 protein, whereas PB specifies the constitutively expressed p110 protein. We show using Stat1(-/-), Stat2(-/-) and IRF9(-/-) ...

journal_title：Virology

authors： George CX,Samuel CE

更新日期：2015-11-01 00:00:00

abstract：:Loss of T cell homeostasis usually precedes the onset of AIDS. We hypothesized that rapid progressors may be transmitted with HIV-1 that is particularly able to perturb T cell homeostasis. To this end, we have tested two transmitted, syncytium-inducing (SI) viral isolates from a rapid progressor in two thymus models. ...

journal_title：Virology

authors： Meissner EG,Duus KM,Gao F,Yu XF,Su L

更新日期：2004-10-10 00:00:00

abstract：:Monoclonal antibodies (MAb) against an O1 Suisse isolate of FMDV were used to identify epitopes on the virus particle and to determine their relative function. Six major antigenic sites containing one or more epitopes were identified using competition ELISA. An epitope relationship is proposed consisting of a trypsin-...

journal_title：Virology

authors： McCullough KC,Crowther JR,Carpenter WC,Brocchi E,Capucci L,De Simone F,Xie Q,McCahon D

更新日期：1987-04-01 00:00:00

abstract：:The V3 loop of HIV-1 gp120 is considered occluded on many primary viruses. However, virus sensitivity to neutralization by different V3 mAbs often varies, indicating that access to V3 is not restricted equally for all antibodies. Here, we have sought to gain a better understanding of these restrictions by determining ...

journal_title：Virology

authors： Pantophlet R,Wrin T,Cavacini LA,Robinson JE,Burton DR

更新日期：2008-11-25 00:00:00

abstract：:We used a series of deletion mutations in the 5' untranslated region of the prototype D type retrovirus, Mason-Pfizer Monkey Virus (MPMV), to analyse RNA encapsidation. A region was identified upstream of the major splice donor which reduced particle production but had a proportionally greater effect on RNA packaging....

journal_title：Virology

authors： Guesdon FM,Greatorex J,Rhee SR,Fisher R,Hunter E,Lever AM

更新日期：2001-09-15 00:00:00

abstract：:Influenza A virus, a respiratory pathogen manipulates various host cellular processes to establish a successful infection in a host. We had reported earlier the interaction of influenza A virus nucleoprotein with host glycolytic enzymes; alpha enolase and pyruvate kinase in A549 cells. Matrix protein (M1), another mul...

journal_title：Virology

authors： Mishra S,Goyal P,Kumar D,Chaudhari R,Rajala MS

更新日期：2020-10-01 00:00:00

abstract：:Mice are used as models for western equine encephalitis virus (WEEV) infection, but high mortality is generally only seen with intracranial or intranasal challenge, while peripheral inoculation results in approximately 50% mortality and is not dose-dependent. Hamsters were therefore studied as a model for WEEV infecti...

journal_title：Virology

authors： Julander JG,Siddharthan V,Blatt LM,Schafer K,Sidwell RW,Morrey JD

更新日期：2007-04-10 00:00:00

abstract：:Pokeweed antiviral protein (PAP) is a ribosome-inactivating protein characterized by its ability to depurinate the sarcin/ricin (S/R) loop of the large rRNA of prokaryotic and eukaryotic ribosomes. Here, a series of PAP mutants were used to examine the relationship between depurination of the S/R loop and inhibition o...

journal_title：Virology

authors： Hudak KA,Hammell AB,Yasenchak J,Tumer NE,Dinman JD

更新日期：2001-01-05 00:00:00

abstract：:The reactivates of human sera with uninduced and phorbol ester (TPA)-induced human herpesvirus-8 (HHV-8)-infected BCBL-1 cells were examined by immunofluorescence assay (IFA) and by radioimmunoprecipitation reactions (RIP). The seroprevalence of HHV-8 infections is low in the United States general population and only ...

journal_title：Virology

authors： Chandran B,Smith MS,Koelle DM,Corey L,Horvat R,Goldstein E

更新日期：1998-03-30 00:00:00

abstract：:Hepatitis B virus large surface protein has the unusual property of accumulating in a particulate form within a preGolgi compartment, leading to marked proliferation of intracellular membranes. We show here that large surface protein activates the promoters for two lipogenic genes that code for farnesyl diphosphate sy...

journal_title：Virology

authors： Foo NC,Yen TS

更新日期：2000-04-10 00:00:00

abstract：:The (guanine-N7)-methyltransferase domain of the vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit D1(498-844) bound to a stimulatory subunit D12. To identify structural elements of the 287-amino-acid D12 subunit that participate in binding and activation of the catalytic subunit, we ...

journal_title：Virology

authors： Saha N,Shuman S

更新日期：2001-08-15 00:00:00

abstract：:The purified genomic dsRNA of bluetongue virus type 1 (BTV 1) was separated into 10 size classes by polyacrylamide gel electrophoresis. These genome segments were recovered individually from the gel, denatured with methylmercuric hydroxide and translated in vitro in a rabbit reticulocyte lysate system. The virus-speci...

journal_title：Virology

authors： Mertens PP,Brown F,Sangar DV

更新日期：1984-05-01 00:00:00

abstract：:Infection of rhesus macaques with attenuated SIVmac is, at present, the only strategy which confers significant protection from challenge with wild-type SIVmac grown in monkey PBMC. However, initial results suggest that the protective mechanism does not develop until late after "vaccination" (approx 10 months). As par...

journal_title：Virology

authors： Norley S,Beer B,Binninger-Schinzel D,Cosma C,Kurth R

更新日期：1996-05-01 00:00:00

abstract：:It has previously been shown that the genome of RF virus, a variant of the human papovavirus, BK, consists of two DNA species, one (R1a) with a deletion corresponding to the early and the other (R2) with a deletion corresponding to the late region of BKV (A. Pater, M.M. Pater, and G. di Mayorca (1980). J. Virol. 36, 4...

journal_title：Virology

authors： Pater A,Pater MM,Chang LS,Slawin K,Di Mayorca G

更新日期：1983-12-01 00:00:00

abstract：:To address the mechanisms of host-virus adaptation and pathogenesis of lentiviral infections, we compared the evolution of the same isolate of simian immunodeficiency virus (SIVsmm9) in two different situations: nonpathogenic infection of its natural host, the sooty mangabey, and AIDS-inducing infection of a new host,...

journal_title：Virology

authors： Courgnaud V,Saurin W,Villinger F,Sonigo P

更新日期：1998-07-20 00:00:00

abstract：:The location of the cistron encoding the genome-linked protein (VPg) in the potyvirus tobacco vein mottling virus (TVMV) was investigated. Precipitation of 125I-labeled VPg with anti-tobacco etch virus 49K nuclear inclusion protein antiserum (which reacts with the NIa nuclear inclusion protein of TVMV) indicated that ...

journal_title：Virology

authors： Shahabuddin M,Shaw JG,Rhoads RE

更新日期：1988-04-01 00:00:00

abstract：:The influenza A virus nucleoprotein previously expressed in Escherichia coli after fusion to 32 heterologous amino acids has now been purified and tested for its ability to form complexes with RNA in vitro. By using a simple filter binding assay, we show that ribonucleoprotein (RNP) complexes form readily with single-...

journal_title：Virology

authors： Kingsbury DW,Jones IM,Murti KG

更新日期：1987-02-01 00:00:00

abstract：:Virus infection may contribute to asthma pathogenesis. In turn, a Th2-polarized pulmonary environment may increase host susceptibility to infection. We used a cockroach antigen (CRA) model of allergic airway disease to test the hypothesis that Th2 cytokine overproduction increases susceptibility to mouse adenovirus ty...

journal_title：Virology

authors： Anderson VE,Nguyen Y,Weinberg JB

更新日期：2009-08-15 00:00:00

abstract：:The N-terminal domains of the NS1 protein of influenza B virus (NS1B protein) and the NS1 protein of influenza A virus (NS1A protein) share one function: binding double-stranded RNA (dsRNA). Here we show that the N-terminal domain of the NS1B protein possesses an additional function that is not shared by its NS1A coun...

journal_title：Virology

authors： Yuan W,Aramini JM,Montelione GT,Krug RM

更新日期：2002-12-20 00:00:00

abstract：:The simian virus 40 (SV40) large T antigen was used as an immunogenic vector to express a herpes simplex virus type 1 (HSV-1) glycoprotein B (gB), H-2Kb-restricted cytotoxic T lymphocyte (CTL) recognition epitope corresponding to amino acid residues 498-505. Immunization of naive, C57BL/6 mice with a cell line, B6/350...

journal_title：Virology

authors： Bonneau RH,Fu TM,Tevethia SS

更新日期：1993-12-01 00:00:00

abstract：:We characterized three subsets of NK cells in blood, and two subsets in mucosal tissues. SIVmac251 infection increased total and CD16(+) NK cells in the blood. In the rectum, we observed a significant increase in total and NKG2A(+) NK cells during SIV infection. In contrast, the NKp44(+) subset significantly depleted ...

journal_title：Virology

authors： Liyanage NP,Gordon SN,Doster MN,Pegu P,Vaccari M,Shukur N,Schifanella L,Pise-Masison CA,Lipinska D,Grubczak K,Moniuszko M,Franchini G

更新日期：2014-02-01 00:00:00

abstract：:Infection of microglial cells by the human immunodeficiency virus (HIV) is supposed to play an important role in the pathogenesis of AIDS-related central nervous system (CNS) complications. So far, however, experimental data about interactions between HIV and ramified microglia from the adult CNS were only occasionall...

journal_title：Virology

authors： Hein A,Martin JP,Koehren F,Bingen A,Dörries R

更新日期：2000-03-15 00:00:00

abstract：:Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be ...

journal_title：Virology

authors： Spiropoulou CF,Ranjan P,Pearce MB,Sealy TK,Albariño CG,Gangappa S,Fujita T,Rollin PE,Nichol ST,Ksiazek TG,Sambhara S

更新日期：2009-09-15 00:00:00

abstract：:The adenine DNA methyltransferase M.CviRI (TGCmA) gene from chlorella virus XZ-6E was cloned into the Autographa californica nuclear polyhedrosis virus (AcMNPV) genome and expressed in Spodoptera frugiperda insect cells under the control of two tandemly arranged viral promoters, the early ETL promoter and the late pol...

journal_title：Virology

authors： Xia Y,Van Etten JL,Dobos P,Ling YY,Krell PJ

更新日期：1993-10-01 00:00:00

abstract：:We have investigated the role of vif in maedi-visna virus (MVV), a lentivirus of sheep, by studying in vitro replication of vif-deleted MVV in several cell types, and the effects of vif deletion on in vivo infection. By measuring RT activity, we found that in comparison to wild-type MVV, growth of vif-deleted MVV was ...

journal_title：Virology

authors： Kristbjörnsdóttir HB,Andrésdóttir V,Svansson V,Torsteinsdóttir S,Matthíasdóttir S,Andrésson OS

更新日期：2004-01-05 00:00:00

abstract：:A number of studies examining interactions of dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (DC-SIGN) with viral pathogens have relied on monocytic transfectants as models for primary DCs. Here we show that the presumed "THP-1" monocytic cells used in these studies are instead Raji B cells. Moreover, we dem...

journal_title：Virology

authors： Wu L,Martin TD,Carrington M,KewalRamani VN

更新日期：2004-01-05 00:00:00

abstract：:The recent identification of a novel human coronavirus responsible of a SARS-like illness in the Middle-East a decade after the SARS pandemic, demonstrates that reemergence of a SARS-like coronavirus from an animal reservoir remains a credible threat. Because SARS is contracted by aerosolized contamination of the resp...

journal_title：Virology

authors： Escriou N,Callendret B,Lorin V,Combredet C,Marianneau P,Février M,Tangy F

更新日期：2014-03-01 00:00:00

abstract：:A dodecapeptide containing the sequence of the C terminus of the nonstructural polyprotein of Sindbis virus has been synthesized and used to immunize rabbits. The antisera obtained precipitated polypeptides from cells infected with the HR strains of Sindbis or with temperature-sensitive mutants ts11 or ts18. Four diff...

journal_title：Virology

authors： Lopez S,Bell JR,Strauss EG,Strauss JH

更新日期：1985-03-01 00:00:00

abstract：:Previously different authors described various flavivirus mutants with high affinity to cell glycosaminoglycans and low neuroinvasiveness in mice that were obtained consequently passages in cell cultures or in ticks. In present study the analysis of TBEV isolates has shown existence of GAG-binding variants in natural ...

journal_title：Virology

authors： Kozlovskaya LI,Osolodkin DI,Shevtsova AS,Romanova LIu,Rogova YV,Dzhivanian TI,Lyapustin VN,Pivanova GP,Gmyl AP,Palyulin VA,Karganova GG

更新日期：2010-03-15 00:00:00