Abstract:
:C57/B1 mice were exposed during pregnancy (gestation days 0-19) to a 20 kHz magnetic field (MF). The asymmetric sawtooth-waveform magnetic field in the exposed racks had a flux density of 15 microT (peak to peak). After 19 days, the exposure was terminated, and the mice were housed individually under normal laboratory conditions. On postnatal day (PD) 1, PD21, and PD308, various neurochemical markers in the brains of the offspring were investigated and the brains weighed. No significant difference was found in the whole brain weight at PD1 or PD21 between exposed offspring and control animals. However, on PD308, a significant decrease in weight of the whole brain was detected in exposed animals. No significant differences were found in the weight of cortex, hippocampus, septum, or cerebellum on any of the sampling occasions, nor were any significant differences detected in protein-, DNA-level, nerve growth factor (NGF), acetylcholine esterase- (AChE), or 2',3'-cyclic nucleotide 3'-phosphodiesterase- (CNP; marker for oligodendrocytes) activities on PD21 in cerebellum. Cortex showed a more complex pattern of response to MF: MF treatment resulted in a decrease in DNA level and increases in the activities of CNP, AChE, and NGF protein. On PD308, the amount of DNA was significantly reduced in MF-treated cerebellum and CNP activity was still enhanced in MF-treated cortex compared to controls. Most of the effects of MF treatment during the embryonic period were similar to those induced by ionizing radiation but much weaker. However, the duration of the exposure required to elucidate the response of different markers to MF seems to be greater and effects appear later during development compared to responses to ionizing radiation.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Dimberg Ydoi
10.1002/bem.2250160409subject
Has Abstractpub_date
1995-01-01 00:00:00pages
263-7issue
4eissn
0197-8462issn
1521-186Xjournal_volume
16pub_type
杂志文章abstract::The effect of 1 Hz, 30 mT pulsed magnetic fields on young adult rat femoral metaphyseal bone thickness was assessed. Ten same litter, female Wistar rats were studied; five of them underwent 30 min magnetic stimulation sessions for 20 consecutive days. The anterior and posterior cortical, as well as trabecular bone tra...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20396
更新日期:2008-07-01 00:00:00
abstract::Several investigators have reported robust, statistically significant results that indicate that weak (approximately 1 microT) magnetic fields (MFs) increase the rate of morphological abnormalities in chick embryos. However, other investigators have reported that weak MFs do not appear to affect embryo morphology at a...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1997)18:6<431::aid-bem5>3.
更新日期:1997-01-01 00:00:00
abstract::Extremely low frequency magnetic fields (ELF MF) have been reported to alter a number of cell signaling pathways, including those involved in proliferation, differentiation and apoptosis where cytosolic free calcium ([Ca(2+)](c)) plays an important role. To better understand the biological conditions under which ELF M...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20248
更新日期:2006-07-01 00:00:00
abstract::The effects of exposure to a 50 Hz magnetic field (maximum of 41.7 to 43.6 mT) on the membrane protein structures of living HeLa cells were studied using attenuated total reflection infrared spectroscopy. One min of such exposure shifted peak absorbance of the amide I band to a smaller wave number, reduced peak absorb...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10120
更新日期:2003-10-01 00:00:00
abstract::Despite experimental evidence supporting ICR-like interactions in biological systems, to date there is no reasonable theoretical explanation for this phenomenon. The parametric resonance approach introduced by Lednev has enjoyed limited success in predicting the response as a function of the ratio of AC magnetic inten...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20406
更新日期:2008-07-01 00:00:00
abstract::The mechanism by which animals detect weak electric and magnetic fields has not yet been elucidated. We propose that transduction of an electric field (E) occurs at the apical membrane of a specialized cell as a consequence of an interaction between the field and glycoproteins bound to the gates of ion channels. Accor...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20310
更新日期:2007-07-01 00:00:00
abstract::In studies investigating adverse reproductive outcomes associated with video display terminal (VDT) usage, amounts of time spent in front of a VDT or magnetic field (MF) levels in front of the VDT are used as surrogate measures of subject's MF exposure. However, the relevance of such surrogates to actual exposures has...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(SICI)1521-186X(1996)17:5<406::AID-BEM8>3.
更新日期:1996-01-01 00:00:00
abstract::The electromagnetic exposure of cell phone users depends on several parameters. One of the most dominant of these is the distance between the cell phone and the head tissue. The pinna can be regarded as a spacer between the top of the phone and the head tissue. The size of this spacer has not yet been systematically s...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20575
更新日期:2010-07-01 00:00:00
abstract::Using a crossover experimental design, we evaluated our earlier findings that exposure to a 30 kV/m, 60 Hz electric field for 12 hours per day, 7 days per week for 6 weeks produced significant changes in the performance rates of social behaviors among young adult male baboons. In the crossover experiment, the former c...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130506
更新日期:1992-01-01 00:00:00
abstract::Radio-frequency electromagnetic radiation (RFR) at 915 and 147 MHz, when sinusoidally amplitude modulated (AM) at 16 Hz, has been shown to enhance release of calcium ions from neuroblastoma cells in culture. The dose-response relation is unusual, consisting of two power-density "windows" in which enhanced efflux occur...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130407
更新日期:1992-01-01 00:00:00
abstract::The aim of our study was to test the feasibility and reliability of personal dosimetry. Twenty-four hour exposure assessment was carried out in 42 children, 57 adolescents, and 64 adults using the Maschek dosimeter prototype. Self-reported exposure to mobile phone frequencies were compared with the dosimetry results. ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20175
更新日期:2006-01-01 00:00:00
abstract::We have studied the effect of extremely low frequency electromagnetic fields (ELF-EMF) in the presence of a second stressor (mild heat shock) on the expression of a lacZ reporter gene under the control of hsp16 or hsp70 promoters in two transgenic strains of C. elegans. The expression of the reporter gene was studied ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(200002)21:2<100::aid-bem4>
更新日期:2000-02-01 00:00:00
abstract::The present study examined the effect on rat cortical synaptosomes of a 2 h exposure to 50-Hz electromagnetic fields (EMFs) with a peak magnetic field of 2 mT. We measured modifications of synaptosomal mitochondrial respiration rate, ATP production, membrane potential, intrasynaptosomal Ca(2+) concentration and free i...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20322
更新日期:2007-09-01 00:00:00
abstract::In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 microTrms/50 Hz did not change nerve growth factor (NGF) induced n...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20073
更新日期:2005-01-01 00:00:00
abstract::To investigate the effects of 1.8 GHz radiofrequency (RF) field on bone microstructure and metabolism of femur in mice, C57BL/6 mice (male, age 4 weeks) were whole-body exposed or sham exposed to 1.8 GHz RF field. Specific absorption rates of whole body and bone were approximately 2.70 and 1.14 W/kg (6 h/day for 28 da...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22125
更新日期:2018-07-01 00:00:00
abstract::The present article reviews the basic principles of a new approach to the characterization of pulmonary disease. This approach is based on the unique nuclear magnetic resonance (NMR) properties of the lung and combines experimental measurements (using specially developed NMR techniques) with theoretical simulations. T...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1521-186x(1999)20:4+<110::aid-bem13>
更新日期:1999-01-01 00:00:00
abstract::There are large disparities between basic restrictions for exposure to extremely low-frequency (0-3 kHz) Electric and Magnetic Fields set by two major international bodies. Both bodies agree that these basic restrictions should prevent neuro-stimulatory effects: the retinal phosphene at frequencies up to a few hundred...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20412
更新日期:2008-09-01 00:00:00
abstract::A 275-MHz exposure system, consisting of a circular waveguide irradiator and a transparent plastic animal cage, has been developed to accommodate rhesus monkeys weighing up to 15 kg. The vertically oriented waveguide is composed primarily of stainless steel and is fitted with an inner cage fabricated from a tubular se...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250050109
更新日期:1984-01-01 00:00:00
abstract::Digital cellular telephones using the GSM (Global System for Mobile Communication) transmit information in bursts of microwaves. This pulsed transmitting mode causes the battery current and currents in the electronics of the apparatus to be pulsed. These pulsed currents produce corresponding pulsed magnetic fields nea...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Conductive nanoparticles may enhance tissue heating during radiofrequency (RF) irradiation. Specific absorption rate (SAR) is known to rise with the electrical conductivity of tissue. However, no studies to date have measured the relationship between complex permittivity and nanoparticle concentration in tissue-like s...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20595
更新日期:2010-12-01 00:00:00
abstract::In the last few years, significant developments have taken place in the field of Wireless Local Area Networks (WLAN), and the popularity of portable devices supporting Wireless Fidelity (Wi-Fi) is continuously growing. At the same time, the number of Active Implanted Medical Devices (AIMD) being placed in patients is ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20601
更新日期:2010-10-01 00:00:00
abstract::Studies have evaluated the electroencephalography (EEG) of humans and laboratory animals during and after Radiofrequency (RF) exposures. Effects of RF exposure on the blood-brain barrier (BBB) have been generally accepted for exposures that are thermalizing. Low level exposures that report alterations of the BBB remai...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.10179
更新日期:2003-01-01 00:00:00
abstract::We developed a new computer wire coding method and then applied it to investigate the suggestion that control selection bias might explain the observed association between wire codes and childhood cancer made in the study conducted by Savitz et al. in the Denver area. The computer wire coding method used a geographic ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Through the use of the non-invasive vibrating probe technique for detecting extracellular ionic currents developed in 1974 [Jaffe and Nuccitelli: J Cell Biol 63:614-628, 1974], embryonic currents have been detected in a wide range of animal systems (recently reviewed in [Nuccitelli, Noninvasive Techniques in Cell Biol...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.2250130714
更新日期:1992-01-01 00:00:00
abstract::Laboratory measurements of electric fields have been carried out around examples of smart meter devices used in Great Britain. The aim was to quantify exposure of people to radiofrequency signals emitted from smart meter devices operating at 2.4 GHz, and then to compare this with international (ICNIRP) health-related ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22044
更新日期:2017-05-01 00:00:00
abstract::We have previously employed the Lorentz-Langevin model to describe the effects of weak exogenous magnetic fields via the classical Lorentz force on a charged ion bound in a harmonic oscillator potential, in the presence of thermal noise forces. Previous analyses predicted that microT-range fields give rise to a rotati...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20494
更新日期:2009-09-01 00:00:00
abstract::The MobilEe-study was the first cross-sectional population-based study to investigate possible health effects of mobile communication networks on children using personal dosimetry. Exposure was assessed every second resulting in 86,400 measurements over 24 h for each participant. Therefore, a functional approach to an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20477
更新日期:2009-05-01 00:00:00
abstract::Heat shock proteins (HSPs) are rapidly induced by a variety of stressors, including heat shock, ethanol, heavy metals, UV, and gamma-radiation. Mitogen-activated protein kinases (MAPKs) are also involved in the stress transduction pathways in all eukaryotes. In this study, we attempted to determine whether radiofreque...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20235
更新日期:2006-10-01 00:00:00
abstract::The temporal variation of a static electric field inside an animal cage was investigated with a newly developed small, simple field meter. The field inside the cage was found to be highly dependent on the surface conductivity of the dielectric material. As the surface of the cage became dirty because of animal occupan...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250020410
更新日期:1981-01-01 00:00:00
abstract::The objective of this study was to investigate if persons with implantable medical devices are intrinsically protected by the current electromagnetic safety guidelines. For inter-laboratory comparisons, the U.S. Food and Drug Administration has defined a generic implant as consisting of an insulated wire with noninsul...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章
doi:10.1002/bem.21695
更新日期:2012-07-01 00:00:00