Abstract:
:We have studied the effect of extremely low frequency electromagnetic fields (ELF-EMF) in the presence of a second stressor (mild heat shock) on the expression of a lacZ reporter gene under the control of hsp16 or hsp70 promoters in two transgenic strains of C. elegans. The expression of the reporter gene was studied by scoring animals with induced beta-galactosidase activity after staining in toto or by biochemical quantitation of the enzyme activity, respectively. In our experimental setup we were able to expose the animals to 50 Hz magnetic flux density of 0-150 microT and at the same time control temperature with high precision (+/-0.1 degrees C). Experimental conditions were defined for which EMF strongly enhances the expression of the reporter gene.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Junkersdorf B,Bauer H,Gutzeit HOdoi
10.1002/(sici)1521-186x(200002)21:2<100::aid-bem4>subject
Has Abstractpub_date
2000-02-01 00:00:00pages
100-6issue
2eissn
0197-8462issn
1521-186Xpii
10.1002/(SICI)1521-186X(200002)21:2<100::AID-BEM4>journal_volume
21pub_type
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
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pub_type: 历史文章,杂志文章
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