Neuronal outgrowth of PC-12 cells after combined treatment with nerve growth factor and a magnetic field: influence of the induced electric field strength.

Abstract:

:In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 microTrms/50 Hz did not change nerve growth factor (NGF) induced neurite outgrowth to a statistically significant extent. These results suggest that further increasing the induced field strength by using either higher flux densities and/or more sophisticated wave forms might be necessary to cause the neuronal response of PC-12 cells, as seen in other experiments.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Schimmelpfeng J,Weibezahn KF,Dertinger H

doi

10.1002/bem.20073

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

74-7

issue

1

eissn

0197-8462

issn

1521-186X

journal_volume

26

pub_type

杂志文章
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