Abstract:
:The effects of millimeter waves (MW) on human keratinocytes were studied in vitro using the HaCaT keratinocyte cell line. MW-induced modulation of keratinocyte function was studied in proliferation, adhesion, chemotaxis, and interleukin-1beta (IL-1beta) production assays. Spontaneous proliferation, adhesion to tissue culture plate, random migration, and IL-8- and RANTES induced chemotaxis were not affected by exposure of cells to millimeter waves under the following conditions: frequency, 61.22 GHz; SAR, 770 W/kg; duration of exposure, 15-30 min. However, MW irradiation resulted in a modest but statistically significant increase in the intracellular level of IL-1beta. These data suggest that exposure of human skin (with keratinocytes being the major component of epidermis) to MW can cause activation of basal keratinocytes resulting in an elevated level of IL-1beta production.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Szabo I,Rojavin MA,Rogers TJ,Ziskin MCdoi
10.1002/bem.62subject
Has Abstractpub_date
2001-07-01 00:00:00pages
358-64issue
5eissn
0197-8462issn
1521-186Xpii
10.1002/bem.62journal_volume
22pub_type
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