Abstract:
:It has been suggested that exposure to electromagnetic fields may be a risk factor for cardiovascular disease in humans. Low density lipoprotein (LDL) modifications such as peroxidation and aggregation have been implicated in the pathogenesis of atherosclerosis. The present study investigated the effects of weak (0.125-0.5 mT) and moderate (1-4 mT) static magnetic fields (SMFs) on LDL oxidation, aggregation and zeta potential in vitro. Our results demonstrated that magnetic flux densities of 0.25 and 0.5 mT decreased, and magnetic flux densities of 3 and 4 mT increased the zeta potential and LDL oxidation in comparison with the control samples. All doses of SMFs increased the LDL aggregation in a time- and dose-dependent manner. It is concluded that SMFs can alter the susceptibility of LDL to oxidation and this alteration is dependent on the applied magnetic flux density. The SMF, in addition to its role in the production and stabilization of free radicals and promotion of lipid peroxidation, may influence the metabolism of lipoproteins and their interaction with other molecules such as apolipoproteins, enzymes and receptors through the alteration of the LDL zeta potential and its particles tendency to aggregation.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Abdi S,Dorranian D,Razavi AE,Naderi GA,Boshtam M,Ghorannevis Mdoi
10.1002/bem.21779subject
Has Abstractpub_date
2013-07-01 00:00:00pages
397-404issue
5eissn
0197-8462issn
1521-186Xjournal_volume
34pub_type
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2006-09-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
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更新日期:2000-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-09-01 00:00:00
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journal_title:Bioelectromagnetics
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更新日期:2010-01-01 00:00:00
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