Abstract:
:To evaluate duration- and dose-dependent effects of continuous exposure to a 60 Hz magnetic field (MF) on the testes in mice, BALB/c male mice were exposed to a 60 Hz MF at 100 μT for 24 h a day for 2, 4, 6, or 8 weeks, and at 2, 20, or 200 μT for 24 h a day for 8 weeks. Any exposures to MF did not significantly affect body or testicular masses. However, the apoptotic cells among testicular germ cells were increased duration-dependent at exposures of 100 μT for 6 and 8 weeks and dose-dependent at exposures of 20 and 200 μT for 8 weeks. The number of sperm in epididymis and the diameter of seminiferous tubule decreased in mice exposed to 100 and 200 μT for 8 weeks, respectively. To induce the apoptosis of testicular germ cell in mice, the minimum dose is 20 μT at continuous exposure to a 60 Hz MF for 8 weeks and the minimum duration is 6 weeks at continuous exposure of 100 μT. Taken together, these results suggest that continuous exposure to a 60 Hz MF might affect, duration- and dose-dependent biological processes including apoptotic cell death and spermatogenesis in the male reproductive system of mice.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Kim HS,Park BJ,Jang HJ,Ipper NS,Kim SH,Kim YJ,Jeon SH,Lee KS,Lee SK,Kim N,Ju YJ,Gimm YM,Kim YWdoi
10.1002/bem.21819subject
Has Abstractpub_date
2014-02-01 00:00:00pages
100-7issue
2eissn
0197-8462issn
1521-186Xjournal_volume
35pub_type
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