Abstract:
:The influence of tissue compression and external thermal modulation on passive detection of breast tumors using medical microwave radiometry was investigated using multi-physics numerical modeling. A three-dimensional numerical model of the pendant breast with 10 and 6 mm diameter tumors at varying depths (15 mm, 30 mm) was analyzed at thermodynamic equilibrium using a circular waveguide as the receive antenna. The contrast in the brightness temperature, ΔTB , between the unhealthy and healthy breasts was found to be significantly more for breast compression alone, compared to thermal modulation of the tissue surface, irrespective of tissue composition, tumor size, and depth. The study also concludes that small deep-seated tumor with very low metabolic activity that is not detectable by a radiometer with 0.1 °C sensitivity could be detected under breast compression and short duration cold stress. Thus, detection of deep-seated breast tumors can be significantly improved under controlled tissue compression with an optional cold stress. Bioelectromagnetics. © 2019 Bioelectromagnetics Society.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Akki RS,Sugumar SP,Venkata KC,Arunachalam Kdoi
10.1002/bem.22184subject
Has Abstractpub_date
2019-05-01 00:00:00pages
260-277issue
4eissn
0197-8462issn
1521-186Xjournal_volume
40pub_type
杂志文章abstract::Our previous studies showed that extremely low frequency magnetic fields (ELF-MFs) inhibited tumor growth and change proportion of splenic regulatory T cells (Treg cells). Here, we focus on the effect of ELF-MFs on lung metastatic melanoma mouse model and the regulatory mechanism of ELF-MFs on the differentiation of T...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21954
更新日期:2016-02-01 00:00:00
abstract::Despite experimental evidence supporting ICR-like interactions in biological systems, to date there is no reasonable theoretical explanation for this phenomenon. The parametric resonance approach introduced by Lednev has enjoyed limited success in predicting the response as a function of the ratio of AC magnetic inten...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20406
更新日期:2008-07-01 00:00:00
abstract::There is extensive literature on possible effects of extremely low-frequency magnetic fields (ELF-MFs) on human cognitive functions. However, due to methodological deficits (e.g., low statistical power, small sample sizes) findings have been inconsistent. In the current study we try to overcome these problems by carry...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,meta分析
doi:10.1002/bem.20543
更新日期:2010-04-01 00:00:00
abstract::The aim of our study was to test the feasibility and reliability of personal dosimetry. Twenty-four hour exposure assessment was carried out in 42 children, 57 adolescents, and 64 adults using the Maschek dosimeter prototype. Self-reported exposure to mobile phone frequencies were compared with the dosimetry results. ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20175
更新日期:2006-01-01 00:00:00
abstract::Heat shock proteins (HSPs) are rapidly induced by a variety of stressors, including heat shock, ethanol, heavy metals, UV, and gamma-radiation. Mitogen-activated protein kinases (MAPKs) are also involved in the stress transduction pathways in all eukaryotes. In this study, we attempted to determine whether radiofreque...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20235
更新日期:2006-10-01 00:00:00
abstract::Extremely low-frequency (ELF) magnetic field exposure systems are usually subject to field disturbances induced by external sources. Here, a method for designing a feedback control system for cancelling the effect of external ELF magnetic field disturbances on the magnetic field over the exposure area is presented. Th...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1997)18:4<299::aid-bem2>3.
更新日期:1997-01-01 00:00:00
abstract::The effects of an extremely low frequency (ELF) magnetic field on the sex hormones and other fertility parameters of adult male Sprague-Dawley rats were investigated. Adult male rats were exposed to a 50 Hz sinusoidal magnetic field at approximately 25 microT (rms) for 18 consecutive weeks. There were no significant e...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20186
更新日期:2006-02-01 00:00:00
abstract::Some numerical and analytical methods used to estimate the internal electric fields and current densities produced within human and animal models by low-frequency electric and magnetic fields are surveyed. A major goal of such modeling is the design of laboratory experiments on cellular systems or animal models to pro...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.2250130705
更新日期:1992-01-01 00:00:00
abstract::Introduction of genetic material into muscle tissue has been extensively researched, including isolation and in vitro expansion of primary myoblasts as a potential source of cells for skeletal and heart muscle tissue engineering applications. In this study, we optimized the electroporation protocol for introduction of...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21936
更新日期:2015-12-01 00:00:00
abstract::No causal treatment for chemotherapy-induced peripheral neuropathy (CIPN) is known. Therefore, there is an urgent need to develop a therapy for CIPN. Only scarce clinical data are available concerning magnetic field therapy (MFT) in this context. We conducted a unicentric, randomized, double-blind, placebo-controlled ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,随机对照试验
doi:10.1002/bem.22005
更新日期:2017-02-01 00:00:00
abstract::There are large disparities between basic restrictions for exposure to extremely low-frequency (0-3 kHz) Electric and Magnetic Fields set by two major international bodies. Both bodies agree that these basic restrictions should prevent neuro-stimulatory effects: the retinal phosphene at frequencies up to a few hundred...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20412
更新日期:2008-09-01 00:00:00
abstract::The mechanism by which animals detect weak electric and magnetic fields has not yet been elucidated. We propose that transduction of an electric field (E) occurs at the apical membrane of a specialized cell as a consequence of an interaction between the field and glycoproteins bound to the gates of ion channels. Accor...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20310
更新日期:2007-07-01 00:00:00
abstract::Both eyes of anesthetized cynomolgus monkeys (Macaca fascicularis) were irradiated with 2.45-GHz microwaves, either pulsed or continuous wave. In vivo corneal endothelial abnormalities were observed by specular microscopy and confirmed through histologic techniques after a 16- to 48-hour postexposure period. Pulsed mi...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250060209
更新日期:1985-01-01 00:00:00
abstract::In this article, the transmembrane voltage induced on erythrocyte, codocyte, ovalocyte and spherocyte cell models exposed to a linearly polarised electromagnetic plane wave of frequency 1800 MHz is calculated. For this purpose, a finite element (FE) numerical technique with adaptive meshing is used. The results show t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20065
更新日期:2004-12-01 00:00:00
abstract::One hundred subjects, males and females with ages ranging between 18 and 48 years, were studied under both field-exposed and sham-exposed conditions. A 50 Hz, 100 mu T magnetic field (MF) was used. To examine the effect of field exposure on performance, a two-alternative, forced-choice, duration-discrimination task wi...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/(SICI)1521-186X(1996)17:2<131::AID-BEM7>3.
更新日期:1996-01-01 00:00:00
abstract::Sixteen pregnant Holstein heifers weighing 521 +/- 46 kg, at 3.3 +/- 0.7 months of gestation and 2.2 +/- 2.0 months of age were confined to wooden metabolism cages and were exposed to a vertical electric field (EF) of 10.0 +/- 0.4 kV/m and an artificial light cycle of 12 h light-12 h dark. The heifers were divided int...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20020
更新日期:2004-05-01 00:00:00
abstract::Mice were exposed in the far field in an anechoic chamber to 2,880-MHz pulsed microwaves 3 to 7.5 h daily, 5 days/week for 60 to 360 h. Three experiments were performed at average power densities of 5 mW/cm2 and six at 10 mW/cm2, corresponding to averaged specific absorption rates (SARs) of 2.25 and 4.50 mW/g, respect...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250040409
更新日期:1983-01-01 00:00:00
abstract::Ozone can be produced by corona discharge either in dry air or when one electrode is submerged in water. Since ozone is toxic, we examined whether ozone production by corona near laboratory animals could reach levels of concern. Male rats were exposed to a corona discharge and the concentration of ozone produced was m...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10161
更新日期:2004-02-01 00:00:00
abstract::Previously, we have reported that exposure to 50 Hz coherent sinusoidal magnetic fields (MF) for 24 h inhibits gap junction intercellular communication (GJIC) in mammalian cells at an intensity of 0.4 mT and enhances the inhibition effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) at 0.2 mT. In the present study, w...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20207
更新日期:2006-05-01 00:00:00
abstract::This paper investigates the effect of relevant physical parameters on transient temperature elevation induced in human tissues by electromagnetic waves in the terahertz (THz) band. The problem is defined by assuming a plane wave, which, during a limited time interval, normally impinges on the surface of a 3-layer mode...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21842
更新日期:2014-07-01 00:00:00
abstract::This study reports the continuous 8-h monitoring of data on extremely low-frequency magnetic fields (ELF-MF) relating to 14 children and 35 teachers in 11 elementary schools in Northern Taiwan. It was anticipated that the subjects in two of these campuses would have elevated exposure to ELF-MF as a result of their clo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20431
更新日期:2008-10-01 00:00:00
abstract::Several effects of power-frequency (50/60 Hz) magnetic fields (PF-MF) of weak intensity have been hypothesized in animals and humans. No valid mechanism, however, has been proposed for an interaction between PF-MF and biological tissues and living beings at intensities relevant to animal and human exposure. Here we pr...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20568
更新日期:2010-07-01 00:00:00
abstract::The main purpose of this study is to investigate potential responses of skin cells to millimeter wave (MMW) radiation increasingly used in the wireless technologies. Primary human skin cells were exposed for 1, 6, or 24 h to 60.4 GHz with an average incident power density of 1.8 mW/cm(2) and an average specific absorp...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20693
更新日期:2012-02-01 00:00:00
abstract::A 275-MHz exposure system, consisting of a circular waveguide irradiator and a transparent plastic animal cage, has been developed to accommodate rhesus monkeys weighing up to 15 kg. The vertically oriented waveguide is composed primarily of stainless steel and is fitted with an inner cage fabricated from a tubular se...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250050109
更新日期:1984-01-01 00:00:00
abstract::Human glioma MO54 cells were used to investigate whether radio frequency (RF) field exposure could activate stress response genes. Cells were exposed to continuous wave 1950 MHz or sham conditions for up to 2 h. Specific absorption rates (SARs) were 1, 2, and 10 W/kg. For the cell growth experiment, cell numbers were ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20077
更新日期:2005-05-01 00:00:00
abstract::We have exposed cultured bone cells to a pulsed electromagnetic field (PEMF) for different times to find the minimal exposure time necessary to stimulate an increase of DNA synthesis. We used two different human osteosarcoma cell lines, TE-85 and MG-63, and human normal osteoblast cell (NHOC) obtained from surgical bo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1999)20:3<177::aid-bem4>3.
更新日期:1999-01-01 00:00:00
abstract::Several investigators have reported robust, statistically significant results that indicate that weak (approximately 1 microT) magnetic fields (MFs) increase the rate of morphological abnormalities in chick embryos. However, other investigators have reported that weak MFs do not appear to affect embryo morphology at a...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1997)18:6<431::aid-bem5>3.
更新日期:1997-01-01 00:00:00
abstract::To assess the effect of a magnetic treatment on pain perception, we compared the sensory threshold in 18 healthy volunteers. We determined the threshold by noninvasive electrical stimulation of the tooth pulp and skin before and after exposure to an altered magnetic field of low intensity and to a sham treatment. Five...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160505
更新日期:1995-01-01 00:00:00
abstract::This study aimed to explore effects of static magnetic fields (SMFs) of moderate intensity (3-50 mT) as biophysical stimulators of proliferation and osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells (MSCs). MSCs were exposed to SMFs of three intensities: 3, 15, and 50 mT. Proliferation w...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21903
更新日期:2015-04-01 00:00:00
abstract::There is growing public concern that radio frequency electromagnetic fields may have adverse biological effects. In the present study eight healthy male students were tested to see whether or not radio frequency electromagnetic fields as used in modern digital wireless telecommunication (GSM standard) have noticeable ...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/bem.51
更新日期:2001-05-01 00:00:00