Effects of a 50 Hz sinusoidal magnetic field on cell adhesion molecule expression in two human osteosarcoma cell lines (MG-63 and Saos-2).

Abstract:

:The possibility that a sinusoidal 50 Hz magnetic field with a magnetic flux density of 0.5 mT can induce variations in the expression of cell adhesion molecules (CAMs) in two human osteosarcoma cell lines (MG-63 and Saos-2) was investigated. In particular, the expression of two important integrins, VLA-2, the receptor for collagen, and VLA-5, the receptor for fibronectin, as well as CD44, were examined in both cell lines after these had been exposed for 7 and 14 days to a 50 Hz, 0.5 mT field. Cell surface morphology (scanning electron microscopy), cell growth characteristics (growth curves and cell cycle phase distribution), and cell death (necrosis and apoptosis) were also examined. The results demonstrate that no variations in surface morphology and cell death occurred between control and exposed cells in both MG-63 and Saos-2 cells, while significant changes were noted in cell growth and fibronectin and CD44 expression in MG-63 cells. The results are discussed in view of the important role that CAMs play in controlling various cancer cell functions, particularly proliferation and metastasis.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Santini MT,Rainaldi G,Ferrante A,Indovina PL,Vecchia P,Donelli G

doi

10.1002/bem.10113

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

327-38

issue

5

eissn

0197-8462

issn

1521-186X

journal_volume

24

pub_type

杂志文章
  • Effects of 60-Hz electric fields on cellular elongation and radial expansion growth in cucurbit roots.

    abstract::Serial longitudinal and transverse sections were prepared from roots of Cucumis sativus and Cucurbita maxima that had been exposed/sham-exposed to 60-Hz electric fields for 0-2 days. Field exposures were selected to produce a 10-20% or a 70-80% growth inhibition in whole roots of both species. Cortical cell length and...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250080108

    authors: Brayman AA,Miller MW,Cox C

    更新日期:1987-01-01 00:00:00

  • Low-Frequency Magnetic Fields in Cars and Office Premises and the Geomagnetic Field Variations.

    abstract::In this study, we measured and analyzed the spectral characteristics of a low-frequency magnetic field (MF) inside several gasoline-powered cars while driving on busy city roads. The spectra obtained upon measurements in the interior of the cars are compared with those measured in office locations at different times o...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.22269

    authors: Sarimov R,Binhi V

    更新日期:2020-07-01 00:00:00

  • Predicted SAR in Sprague-Dawley rat as a function of permittivity values.

    abstract::Specific absorption rate (SAR) value is dependent on permittivity value. However, variability in the published permittivity values for human and animal tissue and the development of sophisticated 3-dimensional digital anatomical models to predict SAR values has resulted in the need to understand how model parameters (...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.66

    authors: Gajsek P,Ziriax JM,Hurt WD,Walters TJ,Mason PA

    更新日期:2001-09-01 00:00:00

  • Pulsed electromagnetic fields stimulation affects BMD and local factor production of rats with disuse osteoporosis.

    abstract::Pulsed electromagnetic fields (PEMF) have been used widely to treat nonunion fractures and related problems in bone healing, as a biological and physical method. With the use of Helmholtz coils and PEMF stimulators to generate uniform time-varying electromagnetic fields, the effects of extremely low frequency electrom...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20535

    authors: Shen WW,Zhao JH

    更新日期:2010-02-01 00:00:00

  • Postmortem changes of the dielectric properties of bovine brain tissues at low radiofrequencies.

    abstract::The dielectric properties of the bovine brain grey and white matter in the frequency range from 20 kHz to 100 MHz were measured at different times following animal death. Changes in the dielectric parameters versus time are interpreted in terms of the reduction of the cell volume fraction that results from either cell...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250070105

    authors: Surowiec A,Stuchly SS,Swarup A

    更新日期:1986-01-01 00:00:00

  • Blockade of sensory neuron action potentials by a static magnetic field in the 10 mT range.

    abstract::To characterize the inhibitory effect of a static magnetic field, action potentials (AP) were elicited by intracellular application of 1 ms depolarizing current pulses of constant amplitude to the somata of adult mouse dorsal root ganglion neurons in monolayer dissociated cell culture. During the control period, < 5% ...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250160108

    authors: McLean MJ,Holcomb RR,Wamil AW,Pickett JD,Cavopol AV

    更新日期:1995-01-01 00:00:00

  • Personal exposure to mobile communication networks and well-being in children--a statistical analysis based on a functional approach.

    abstract::The MobilEe-study was the first cross-sectional population-based study to investigate possible health effects of mobile communication networks on children using personal dosimetry. Exposure was assessed every second resulting in 86,400 measurements over 24 h for each participant. Therefore, a functional approach to an...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20477

    authors: Kühnlein A,Heumann C,Thomas S,Heinrich S,Radon K

    更新日期:2009-05-01 00:00:00

  • Electromagnetic millimeter wave induced hypoalgesia: frequency dependence and involvement of endogenous opioids.

    abstract::Millimeter wave treatment (MMWT) is based on the systemic biological effects that develop following local skin exposure to low power electromagnetic waves in the millimeter range. In the present set of experiments, the hypoalgesic effect of this treatment was analyzed in mice. The murine nose area was exposed to MMW o...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20389

    authors: Radzievsky AA,Gordiienko OV,Alekseev S,Szabo I,Cowan A,Ziskin MC

    更新日期:2008-05-01 00:00:00

  • Correlation between pulsed electromagnetic fields exposure time and cell proliferation increase in human osteosarcoma cell lines and human normal osteoblast cells in vitro.

    abstract::We have exposed cultured bone cells to a pulsed electromagnetic field (PEMF) for different times to find the minimal exposure time necessary to stimulate an increase of DNA synthesis. We used two different human osteosarcoma cell lines, TE-85 and MG-63, and human normal osteoblast cell (NHOC) obtained from surgical bo...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/(sici)1521-186x(1999)20:3<177::aid-bem4>3.

    authors: De Mattei M,Caruso A,Traina GC,Pezzetti F,Baroni T,Sollazzo V

    更新日期:1999-01-01 00:00:00

  • Neurobiological effects of pulsed magnetic field on diabetes-induced neuropathy.

    abstract::In the clinic, although several pharmacological agents or surgical procedures are used to treat diabetes and diabetes-induced neuropathic pain, their success has been limited. Therefore, development of different alternatives in treatments is very important. The purpose of this study was to determine the efficacy of pu...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20524

    authors: Mert T,Gunay I,Ocal I

    更新日期:2010-01-01 00:00:00

  • Rate of occurrence of transient magnetic field events in U.S. residences.

    abstract::Recent interest in the transient magnetic field events produced by electrical switching events in residential and occupational environments has been kindled by the possibility that these fields may explain observed associations between childhood cancer and wire codes. This paper reports the results of a study in which...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/(sici)1521-186x(200004)21:3<197::aid-bem7>

    authors: Kaune WT,Bracken TD,Senior RS,Rankin RF,Niple JC,Kavet R

    更新日期:2000-04-01 00:00:00

  • New theoretical treatment of ion resonance phenomena.

    abstract::Despite experimental evidence supporting ICR-like interactions in biological systems, to date there is no reasonable theoretical explanation for this phenomenon. The parametric resonance approach introduced by Lednev has enjoyed limited success in predicting the response as a function of the ratio of AC magnetic inten...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20406

    authors: Vincze G,Szasz A,Liboff AR

    更新日期:2008-07-01 00:00:00

  • Magnetic field exposure assessment for adult residents of Maine who live near and far away from overhead transmission lines.

    abstract::Sixty-Hz magnetic field exposures were measured for 45 adult residents of Maine. Thirty of the subjects resided near rights-of-way (ROWs) with either 345- and 115-kV transmission lines, or ROWs with only 115-kV transmission lines; fifteen resided far from any transmission lines. Personal exposure data for a single 24-...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250130106

    authors: Kavet R,Silva JM,Thornton D

    更新日期:1992-01-01 00:00:00

  • Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia: A randomized controlled study.

    abstract::Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were al...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/bem.22127

    authors: Multanen J,Häkkinen A,Heikkinen P,Kautiainen H,Mustalampi S,Ylinen J

    更新日期:2018-07-01 00:00:00

  • SAR versus S(inc): What is the appropriate RF exposure metric in the range 1-10 GHz? Part I: Using planar body models.

    abstract::This is the first of two articles addressing the most appropriate crossover frequency at which incident power flux density (S(inc)) replaces the spatial peak value of the specific energy absorption rate (SAR) averaged over 1 or 10 g (i.e., peak 1 or 10 g SAR) as the basic restriction for protecting against radiofreque...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20578

    authors: Anderson V,Croft R,McIntosh RL

    更新日期:2010-09-01 00:00:00

  • Dose dependence of acetylcholinesterase activity in neuroblastoma cells exposed to modulated radio-frequency electromagnetic radiation.

    abstract::Radio-frequency electromagnetic radiation (RFR) at 915 and 147 MHz, when sinusoidally amplitude modulated (AM) at 16 Hz, has been shown to enhance release of calcium ions from neuroblastoma cells in culture. The dose-response relation is unusual, consisting of two power-density "windows" in which enhanced efflux occur...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250130407

    authors: Dutta SK,Das K,Ghosh B,Blackman CF

    更新日期:1992-01-01 00:00:00

  • Time trends (1998-2007) in brain cancer incidence rates in relation to mobile phone use in England.

    abstract::Mobile phone use in the United Kingdom and other countries has risen steeply since the early 1990's when the first digital mobile phones were introduced. There is an ongoing controversy about whether radio frequency (RF) exposure from mobile phones increases the risk of brain cancer. However, given the widespread use ...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20648

    authors: de Vocht F,Burstyn I,Cherrie JW

    更新日期:2011-07-01 00:00:00

  • A model for radiofrequency electromagnetic field predictions at outdoor and indoor locations in the context of epidemiological research.

    abstract::We present a geospatial model to predict the radiofrequency electromagnetic field from fixed site transmitters for use in epidemiological exposure assessment. The proposed model extends an existing model toward the prediction of indoor exposure, that is, at the homes of potential study participants. The model is based...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20552

    authors: Bürgi A,Frei P,Theis G,Mohler E,Braun-Fahrländer C,Fröhlich J,Neubauer G,Egger M,Röösli M

    更新日期:2010-04-01 00:00:00

  • Occupational exposure levels of static magnetic field during routine MRI examination in 3T MR system.

    abstract::Occupational exposure to the high static magnetic fields (SMFs) during magnetic resonance imaging (MRI) examinations raises concerns of adverse health effects. In this study, personal exposure monitoring of the magnetic fields during routine examinations in two 3 T MRI systems was carried out. A three-axis Hall magnet...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章,多中心研究

    doi:10.1002/bem.21817

    authors: Yamaguchi-Sekino S,Nakai T,Imai S,Izawa S,Okuno T

    更新日期:2014-01-01 00:00:00

  • Neuronal outgrowth of PC-12 cells after combined treatment with nerve growth factor and a magnetic field: influence of the induced electric field strength.

    abstract::In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 microTrms/50 Hz did not change nerve growth factor (NGF) induced n...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.20073

    authors: Schimmelpfeng J,Weibezahn KF,Dertinger H

    更新日期:2005-01-01 00:00:00

  • Millimeter microwave effect on ion transport across lipid bilayer membranes.

    abstract::The effects of millimeter microwaves in the frequency range of 54-76 GHz on capacitance and conductance of lipid bilayer membranes (BLM) were studied. Some of the membranes were modified by gramicidin A and amphotericin B or by tetraphenylboron anions (TPhB-). The millimeter microwaves were pulse-modulated (PW) at rep...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250160209

    authors: Alekseev SI,Ziskin MC

    更新日期:1995-01-01 00:00:00

  • Electric field exposure alters serum melatonin but not pineal melatonin synthesis in male rats.

    abstract::Sprague-Dawley male rats, maintained in a 14:10 h light:dark cycle were exposed for 30 days (starting at 56 days of age) to a 65 kV/m, 60 Hz electric field or to a sham field for 20 h/day beginning at dark onset. Pineal N-acetyltransferase (NAT), hydroxy-indole-o-methyl transferase (HIOMT), and melatonin as well as se...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250150506

    authors: Grota LJ,Reiter RJ,Keng P,Michaelson S

    更新日期:1994-01-01 00:00:00

  • Residential EMF exposure and childhood leukemia: meta-analysis and population attributable risk.

    abstract::The controversy over the possible association between magnetic field exposure and childhood leukemia has led several researchers to summarize the literature using meta-analysis. This paper reviews these previous meta-analyses and extends them by adding results from four studies published since the most recent analysis...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章,meta分析

    doi:10.1002/1521-186x(2001)22:5+<::aid-bem1026>3.3.co;

    authors: Wartenberg D

    更新日期:2001-01-01 00:00:00

  • Local tissue temperature increase of a generic implant compared to the basic restrictions defined in safety guidelines.

    abstract::The objective of this study was to investigate if persons with implantable medical devices are intrinsically protected by the current electromagnetic safety guidelines. For inter-laboratory comparisons, the U.S. Food and Drug Administration has defined a generic implant as consisting of an insulated wire with noninsul...

    journal_title:Bioelectromagnetics

    pub_type: 临床试验,杂志文章

    doi:10.1002/bem.21695

    authors: Kyriakou A,Christ A,Neufeld E,Kuster N

    更新日期:2012-07-01 00:00:00

  • Pulsed magnetic field enhances therapeutic efficiency of mesenchymal stem cells in chronic neuropathic pain model.

    abstract::Cell-based or magnetic field therapies as alternative approaches to pain management have been tested in several experimental pain models. The aim of this study therefore was to investigate the actions of the cell-based therapy (adipose tissue derived mesenchymal stem cells; ADMSC) or pulsed magnetic field (PMF) therap...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.22038

    authors: Mert T,Kurt AH,Altun İ,Celik A,Baran F,Gunay I

    更新日期:2017-05-01 00:00:00

  • Pulsed subcutaneous electrical stimulation in spinal cord injury: preliminary results.

    abstract::The treatment of long-term, stable para- and quadriplegics with pulsed electrical stimulation for pain control resulted in, anecdotally, a significant number of these individuals showing increased motor function as well as sensory awareness. This small pilot study was conducted in order to assess the hypothesis that p...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250080206

    authors: Ellis W

    更新日期:1987-01-01 00:00:00

  • Proflavin and microwave radiation: absence of a mutagenic interaction.

    abstract::The potential ability of radiofrequency electromagnetic radiation (RFR) in the microwave range to induce mutagenesis, chromosomal aberrations, and sister chromatid exchanges in mammalian cells is being explored in our laboratories. In addition, we have also been examining the ability of simultaneous exposure to RFR an...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250110206

    authors: Meltz ML,Eagan P,Erwin DN

    更新日期:1990-01-01 00:00:00

  • Resonant ac-dc magnetic fields: calculated response.

    abstract::An elementary model consisting of one charged particle in a viscous medium exposed to weak ac-dc low-frequency magnetic fields is analyzed to identify and explain the fundamental characteristics of the physical mechanisms that result in a resonance response, which is similar to the familiar cyclotron resonance. The mo...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250090402

    authors: Durney CH,Rushforth CK,Anderson AA

    更新日期:1988-01-01 00:00:00

  • Immunological effects of amplitude-modulated radio frequency radiation: B lymphocyte capping.

    abstract::B lymphocytes collected from normal ICR Swiss mouse spleens were exposed in vitro in a Crawford cell to 147-MHz radiofrequency (RF) radiation, amplitude modulated by a 9-, 16-, or 60-Hz sine wave. The power densities ranged between 0.11 and 48 mW/cm2. The irradiated samples and the controls were maintained at 37 degre...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.2250040206

    authors: Sultan MF,Cain CA,Tompkins WA

    更新日期:1983-01-01 00:00:00

  • Effects of high power microwave pulses on synaptic transmission and long term potentiation in hippocampus.

    abstract::Effects of short, extremely high power microwave pulses (EHPP) on neuronal network function were explored by electrophysiological techniques in the isolated rat hippocampal slice model. Population spikes (PS) in the CA1 area were evoked by repeated stimulation (1 per 30 s) of the Schaffer collateral pathway. A brief t...

    journal_title:Bioelectromagnetics

    pub_type: 杂志文章

    doi:10.1002/bem.10079

    authors: Pakhomov AG,Doyle J,Stuck BE,Murphy MR

    更新日期:2003-04-01 00:00:00