Abstract:
:The possibility that a sinusoidal 50 Hz magnetic field with a magnetic flux density of 0.5 mT can induce variations in the expression of cell adhesion molecules (CAMs) in two human osteosarcoma cell lines (MG-63 and Saos-2) was investigated. In particular, the expression of two important integrins, VLA-2, the receptor for collagen, and VLA-5, the receptor for fibronectin, as well as CD44, were examined in both cell lines after these had been exposed for 7 and 14 days to a 50 Hz, 0.5 mT field. Cell surface morphology (scanning electron microscopy), cell growth characteristics (growth curves and cell cycle phase distribution), and cell death (necrosis and apoptosis) were also examined. The results demonstrate that no variations in surface morphology and cell death occurred between control and exposed cells in both MG-63 and Saos-2 cells, while significant changes were noted in cell growth and fibronectin and CD44 expression in MG-63 cells. The results are discussed in view of the important role that CAMs play in controlling various cancer cell functions, particularly proliferation and metastasis.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Santini MT,Rainaldi G,Ferrante A,Indovina PL,Vecchia P,Donelli Gdoi
10.1002/bem.10113subject
Has Abstractpub_date
2003-07-01 00:00:00pages
327-38issue
5eissn
0197-8462issn
1521-186Xjournal_volume
24pub_type
杂志文章abstract::Serial longitudinal and transverse sections were prepared from roots of Cucumis sativus and Cucurbita maxima that had been exposed/sham-exposed to 60-Hz electric fields for 0-2 days. Field exposures were selected to produce a 10-20% or a 70-80% growth inhibition in whole roots of both species. Cortical cell length and...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250080108
更新日期:1987-01-01 00:00:00
abstract::In this study, we measured and analyzed the spectral characteristics of a low-frequency magnetic field (MF) inside several gasoline-powered cars while driving on busy city roads. The spectra obtained upon measurements in the interior of the cars are compared with those measured in office locations at different times o...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22269
更新日期:2020-07-01 00:00:00
abstract::Specific absorption rate (SAR) value is dependent on permittivity value. However, variability in the published permittivity values for human and animal tissue and the development of sophisticated 3-dimensional digital anatomical models to predict SAR values has resulted in the need to understand how model parameters (...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.66
更新日期:2001-09-01 00:00:00
abstract::Pulsed electromagnetic fields (PEMF) have been used widely to treat nonunion fractures and related problems in bone healing, as a biological and physical method. With the use of Helmholtz coils and PEMF stimulators to generate uniform time-varying electromagnetic fields, the effects of extremely low frequency electrom...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20535
更新日期:2010-02-01 00:00:00
abstract::The dielectric properties of the bovine brain grey and white matter in the frequency range from 20 kHz to 100 MHz were measured at different times following animal death. Changes in the dielectric parameters versus time are interpreted in terms of the reduction of the cell volume fraction that results from either cell...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250070105
更新日期:1986-01-01 00:00:00
abstract::To characterize the inhibitory effect of a static magnetic field, action potentials (AP) were elicited by intracellular application of 1 ms depolarizing current pulses of constant amplitude to the somata of adult mouse dorsal root ganglion neurons in monolayer dissociated cell culture. During the control period, < 5% ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160108
更新日期:1995-01-01 00:00:00
abstract::The MobilEe-study was the first cross-sectional population-based study to investigate possible health effects of mobile communication networks on children using personal dosimetry. Exposure was assessed every second resulting in 86,400 measurements over 24 h for each participant. Therefore, a functional approach to an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20477
更新日期:2009-05-01 00:00:00
abstract::Millimeter wave treatment (MMWT) is based on the systemic biological effects that develop following local skin exposure to low power electromagnetic waves in the millimeter range. In the present set of experiments, the hypoalgesic effect of this treatment was analyzed in mice. The murine nose area was exposed to MMW o...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20389
更新日期:2008-05-01 00:00:00
abstract::We have exposed cultured bone cells to a pulsed electromagnetic field (PEMF) for different times to find the minimal exposure time necessary to stimulate an increase of DNA synthesis. We used two different human osteosarcoma cell lines, TE-85 and MG-63, and human normal osteoblast cell (NHOC) obtained from surgical bo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1999)20:3<177::aid-bem4>3.
更新日期:1999-01-01 00:00:00
abstract::In the clinic, although several pharmacological agents or surgical procedures are used to treat diabetes and diabetes-induced neuropathic pain, their success has been limited. Therefore, development of different alternatives in treatments is very important. The purpose of this study was to determine the efficacy of pu...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20524
更新日期:2010-01-01 00:00:00
abstract::Recent interest in the transient magnetic field events produced by electrical switching events in residential and occupational environments has been kindled by the possibility that these fields may explain observed associations between childhood cancer and wire codes. This paper reports the results of a study in which...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(200004)21:3<197::aid-bem7>
更新日期:2000-04-01 00:00:00
abstract::Despite experimental evidence supporting ICR-like interactions in biological systems, to date there is no reasonable theoretical explanation for this phenomenon. The parametric resonance approach introduced by Lednev has enjoyed limited success in predicting the response as a function of the ratio of AC magnetic inten...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20406
更新日期:2008-07-01 00:00:00
abstract::Sixty-Hz magnetic field exposures were measured for 45 adult residents of Maine. Thirty of the subjects resided near rights-of-way (ROWs) with either 345- and 115-kV transmission lines, or ROWs with only 115-kV transmission lines; fifteen resided far from any transmission lines. Personal exposure data for a single 24-...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130106
更新日期:1992-01-01 00:00:00
abstract::Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were al...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,随机对照试验
doi:10.1002/bem.22127
更新日期:2018-07-01 00:00:00
abstract::This is the first of two articles addressing the most appropriate crossover frequency at which incident power flux density (S(inc)) replaces the spatial peak value of the specific energy absorption rate (SAR) averaged over 1 or 10 g (i.e., peak 1 or 10 g SAR) as the basic restriction for protecting against radiofreque...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20578
更新日期:2010-09-01 00:00:00
abstract::Radio-frequency electromagnetic radiation (RFR) at 915 and 147 MHz, when sinusoidally amplitude modulated (AM) at 16 Hz, has been shown to enhance release of calcium ions from neuroblastoma cells in culture. The dose-response relation is unusual, consisting of two power-density "windows" in which enhanced efflux occur...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130407
更新日期:1992-01-01 00:00:00
abstract::Mobile phone use in the United Kingdom and other countries has risen steeply since the early 1990's when the first digital mobile phones were introduced. There is an ongoing controversy about whether radio frequency (RF) exposure from mobile phones increases the risk of brain cancer. However, given the widespread use ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20648
更新日期:2011-07-01 00:00:00
abstract::We present a geospatial model to predict the radiofrequency electromagnetic field from fixed site transmitters for use in epidemiological exposure assessment. The proposed model extends an existing model toward the prediction of indoor exposure, that is, at the homes of potential study participants. The model is based...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20552
更新日期:2010-04-01 00:00:00
abstract::Occupational exposure to the high static magnetic fields (SMFs) during magnetic resonance imaging (MRI) examinations raises concerns of adverse health effects. In this study, personal exposure monitoring of the magnetic fields during routine examinations in two 3 T MRI systems was carried out. A three-axis Hall magnet...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,多中心研究
doi:10.1002/bem.21817
更新日期:2014-01-01 00:00:00
abstract::In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 microTrms/50 Hz did not change nerve growth factor (NGF) induced n...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20073
更新日期:2005-01-01 00:00:00
abstract::The effects of millimeter microwaves in the frequency range of 54-76 GHz on capacitance and conductance of lipid bilayer membranes (BLM) were studied. Some of the membranes were modified by gramicidin A and amphotericin B or by tetraphenylboron anions (TPhB-). The millimeter microwaves were pulse-modulated (PW) at rep...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160209
更新日期:1995-01-01 00:00:00
abstract::Sprague-Dawley male rats, maintained in a 14:10 h light:dark cycle were exposed for 30 days (starting at 56 days of age) to a 65 kV/m, 60 Hz electric field or to a sham field for 20 h/day beginning at dark onset. Pineal N-acetyltransferase (NAT), hydroxy-indole-o-methyl transferase (HIOMT), and melatonin as well as se...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250150506
更新日期:1994-01-01 00:00:00
abstract::The controversy over the possible association between magnetic field exposure and childhood leukemia has led several researchers to summarize the literature using meta-analysis. This paper reviews these previous meta-analyses and extends them by adding results from four studies published since the most recent analysis...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,meta分析
doi:10.1002/1521-186x(2001)22:5+<::aid-bem1026>3.3.co;
更新日期:2001-01-01 00:00:00
abstract::The objective of this study was to investigate if persons with implantable medical devices are intrinsically protected by the current electromagnetic safety guidelines. For inter-laboratory comparisons, the U.S. Food and Drug Administration has defined a generic implant as consisting of an insulated wire with noninsul...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章
doi:10.1002/bem.21695
更新日期:2012-07-01 00:00:00
abstract::Cell-based or magnetic field therapies as alternative approaches to pain management have been tested in several experimental pain models. The aim of this study therefore was to investigate the actions of the cell-based therapy (adipose tissue derived mesenchymal stem cells; ADMSC) or pulsed magnetic field (PMF) therap...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22038
更新日期:2017-05-01 00:00:00
abstract::The treatment of long-term, stable para- and quadriplegics with pulsed electrical stimulation for pain control resulted in, anecdotally, a significant number of these individuals showing increased motor function as well as sensory awareness. This small pilot study was conducted in order to assess the hypothesis that p...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250080206
更新日期:1987-01-01 00:00:00
abstract::The potential ability of radiofrequency electromagnetic radiation (RFR) in the microwave range to induce mutagenesis, chromosomal aberrations, and sister chromatid exchanges in mammalian cells is being explored in our laboratories. In addition, we have also been examining the ability of simultaneous exposure to RFR an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250110206
更新日期:1990-01-01 00:00:00
abstract::An elementary model consisting of one charged particle in a viscous medium exposed to weak ac-dc low-frequency magnetic fields is analyzed to identify and explain the fundamental characteristics of the physical mechanisms that result in a resonance response, which is similar to the familiar cyclotron resonance. The mo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250090402
更新日期:1988-01-01 00:00:00
abstract::B lymphocytes collected from normal ICR Swiss mouse spleens were exposed in vitro in a Crawford cell to 147-MHz radiofrequency (RF) radiation, amplitude modulated by a 9-, 16-, or 60-Hz sine wave. The power densities ranged between 0.11 and 48 mW/cm2. The irradiated samples and the controls were maintained at 37 degre...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250040206
更新日期:1983-01-01 00:00:00
abstract::Effects of short, extremely high power microwave pulses (EHPP) on neuronal network function were explored by electrophysiological techniques in the isolated rat hippocampal slice model. Population spikes (PS) in the CA1 area were evoked by repeated stimulation (1 per 30 s) of the Schaffer collateral pathway. A brief t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10079
更新日期:2003-04-01 00:00:00