Immunologic and hematopoietic alterations by 2,450-MHz electromagnetic radiation.

Abstract:

:A biphasic modulation of responsiveness of spleen lymphocytes to mitogens was observed in mice exposed to 2,450-MHz radiation at power densities of 5-15 mW/cm2 over various periods ranging between one and 17 days. This modulated phenomenon may be explained on the basis of 1) suppression of lymphocyte response to microwave-activated macrophages which persists throughout the entire course of radiation, and 2) concurrent progressive direct stimulation of lymphocytes which culminates around day 9 of exposure. Tumor cytotoxicity of killer lymphocytes from mice exposed to five or nine days of radiation did not appear different from sham controls. The highly proliferative hematopoietic marrow cells were sensitive to microwave radiation. Nine days of exposure to radiation (15 mW/cm2) reduced the colony-forming units of myeloid and erythroid series by 50%. This observation may offer a new and more sensitive assay for studying biological effects of electromagnetic radiation.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Huang AT,Mold NG

doi

10.1002/bem.2250010108

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

77-87

issue

1

eissn

0197-8462

issn

1521-186X

journal_volume

1

pub_type

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