Abstract:
:The effects of hyperthermia, alone and in conjunction with microwave exposure, on brain energetics were studied in anesthetized male Sprague-Dawley rats. The effect of temperature on adenosine triphosphate concentration [ATP] and creatine phosphate concentration [CP] was determined in the brains of rats that were maintained at 35.6, 37.0, 39.0, and 41.0 degrees C. At 37, 39, and 41 degrees C brain [ATP] and [CP] were down 6.0, 10.8, and 29.2%, and 19.6, 28.7, and 44%, respectively, from the 35.6 degrees C control concentrations. Exposure of the brain to 591-MHz radiation at 13.8 mW/cm2 for 0.5, 1.0, 3.0, and 5.0 min caused further decreases (below those observed for 30 degrees C hyperthermia only) of 16.0, 29.8, 22.5, and 12.3% in brain [ATP], and of 15.6, 25.1, 21.4, and 25.9% in brain [CP] after 0.5, 1.0, 3.0, and 5.0 min, respectively. Recording of brain reduced nicotinamide adenine dinucleotide (NADH) fluorescence before, during, and after microwave exposure showed an increase in NADH fluorescence during microwave exposure that returned to preexposure levels within 1 min postexposure. Continuous recording of brain temperatures during microwave exposures showed that brain temperature varied between -0.1 and +0.05 degrees C. Since the microwave exposures did not induce tissue hyperthermia, it is concluded that direct microwave interaction at the subcellular level is responsible for the observed decrease in [ATP] and [CP].
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Sanders AP,Joines WTdoi
10.1002/bem.2250050107subject
Has Abstractpub_date
1984-01-01 00:00:00pages
63-70issue
1eissn
0197-8462issn
1521-186Xjournal_volume
5pub_type
杂志文章abstract::Studies have evaluated the electroencephalography (EEG) of humans and laboratory animals during and after Radiofrequency (RF) exposures. Effects of RF exposure on the blood-brain barrier (BBB) have been generally accepted for exposures that are thermalizing. Low level exposures that report alterations of the BBB remai...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.10179
更新日期:2003-01-01 00:00:00
abstract::Experiments were conducted to see whether the cellular response to electromagnetic (EM) fields occurs through a detection process involving temporal sensing. L929 cells were exposed to 60 Hz magnetic fields and the enhancement of ornithine decarboxylase (ODC) activity was measured to determine cellular response to the...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1997)18:5<388::aid-bem6>3.
更新日期:1997-01-01 00:00:00
abstract::This study examined the time dependence effects of exposure to radiofrequency radiation (RFR) emitted by standard GSM cellular phones on the cognitive functions of humans. A total of 48 healthy right-handed male subjects performed a spatial working memory task (that required either a left-hand or a right-hand response...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20458
更新日期:2009-04-01 00:00:00
abstract::The effects of millimeter microwaves in the frequency range of 54-76 GHz on capacitance and conductance of lipid bilayer membranes (BLM) were studied. Some of the membranes were modified by gramicidin A and amphotericin B or by tetraphenylboron anions (TPhB-). The millimeter microwaves were pulse-modulated (PW) at rep...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160209
更新日期:1995-01-01 00:00:00
abstract::The possible effects of repeated night-time exposure to an extremely low frequency magnetic field (ELF-MF) on melatonin were investigated in nine healthy male subjects aged 23-37 yr. The 16-week experiment consisted of 3 weeks of pre-exposure, 11 weeks of night-time exposure to MF generated from a nonheated electric s...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/1521-186x(200102)22:2<138::aid-bem1017>3.0
更新日期:2001-02-01 00:00:00
abstract::A biphasic modulation of responsiveness of spleen lymphocytes to mitogens was observed in mice exposed to 2,450-MHz radiation at power densities of 5-15 mW/cm2 over various periods ranging between one and 17 days. This modulated phenomenon may be explained on the basis of 1) suppression of lymphocyte response to micro...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250010108
更新日期:1980-01-01 00:00:00
abstract::We investigated the effects on human keratinocytes (HaCaT) of exposure to a sinusoidal magnetic field of 2 mT (50 Hz). These cells are a good model for studying interaction of nonionising radiation, because they are not shielded from fields in vivo and also because they are resistant to both mechanical and thermal sti...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10023
更新日期:2002-05-01 00:00:00
abstract::B lymphocytes collected from normal ICR Swiss mouse spleens were exposed in vitro in a Crawford cell to 147-MHz radiofrequency (RF) radiation, amplitude modulated by a 9-, 16-, or 60-Hz sine wave. The power densities ranged between 0.11 and 48 mW/cm2. The irradiated samples and the controls were maintained at 37 degre...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250040206
更新日期:1983-01-01 00:00:00
abstract::There are large disparities between basic restrictions for exposure to extremely low-frequency (0-3 kHz) Electric and Magnetic Fields set by two major international bodies. Both bodies agree that these basic restrictions should prevent neuro-stimulatory effects: the retinal phosphene at frequencies up to a few hundred...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20412
更新日期:2008-09-01 00:00:00
abstract::The temperature distribution inside a lossy sphere resulting from the absorption of microwave energy was approximated by successive numerical iterations. of the thermal energy equation. Heat transfer within the sphere by conduction was considered. In the model energy was not dissipated by convection but was contained ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250010309
更新日期:1980-01-01 00:00:00
abstract::The effect of 1 Hz, 30 mT pulsed magnetic fields on young adult rat femoral metaphyseal bone thickness was assessed. Ten same litter, female Wistar rats were studied; five of them underwent 30 min magnetic stimulation sessions for 20 consecutive days. The anterior and posterior cortical, as well as trabecular bone tra...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20396
更新日期:2008-07-01 00:00:00
abstract::Most of the research concerning magnetic antinociception was focused on brief exposure less than 1 h. The main purpose of the present study was to determine the effect of extremely low frequency (ELF) magnetic field (MF) repeated exposures on rats in inducing antinociception and to find the effective analgesic "time w...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20232
更新日期:2006-09-01 00:00:00
abstract::We exposed normal human epidermal keratinocytes to short duration, high frequency, and low amplitude electromagnetic fields, similar to that used by mobile phone technologies. We paid particular attention to the control of the characteristics of the electromagnetic environment generated within a mode stirred reverbera...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20641
更新日期:2011-05-01 00:00:00
abstract::The impedance spectroscopy technique (IST) was used for studying the effect of a 0.5 T magnetic field on the electrical properties of whole human blood. A Solartron SI 1260 spectrometer was used to measure the impedance spectra of magnetic field exposed blood samples compared to non-exposed samples. An equivalent elec...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20132
更新日期:2005-10-01 00:00:00
abstract::Through the use of the non-invasive vibrating probe technique for detecting extracellular ionic currents developed in 1974 [Jaffe and Nuccitelli: J Cell Biol 63:614-628, 1974], embryonic currents have been detected in a wide range of animal systems (recently reviewed in [Nuccitelli, Noninvasive Techniques in Cell Biol...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.2250130714
更新日期:1992-01-01 00:00:00
abstract::The effects of exposure to clinical magnetic resonance imaging (MRI) on analgesia induced by the mu opiate agonist, fentanyl, was examined in mice. During the dark period, adult male mice were exposed for 23.2 min to the time-varying (0.6 T/sec) magnetic field (TVMF) component of the MRI procedure. Following this expo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250090208
更新日期:1988-01-01 00:00:00
abstract::In this acceptance address for the Bioelectromagnetics Society's 2001 d'Arsonval Award, Dr. Tenforde reviews the highlights of the nonionizing field aspects of his research and scientific service career. These are focused in four areas: (a). development and application of microelectrophoretic methods to probe the surf...
journal_title:Bioelectromagnetics
pub_type: 传,历史文章
doi:10.1002/bem.10090
更新日期:2003-01-01 00:00:00
abstract::Accumulating evidence does not yet confirm the effect of power line frequency magnetic field (MF) on human health and fertility. We recently reported that, at continuous 60 Hz MF exposure in mice, the dose given as magnetic flux density (tesla; T) and duration of exposure was related to induce testicular germ cell apo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22146
更新日期:2018-10-01 00:00:00
abstract::The objective of this study was to develop a model for testing various hypotheses concerning possible mechanisms whereby electromagnetic fields might induce suppression of nighttime melatonin production in rodents. A published method for digesting freshly obtained pineal glands to the single cell level was modified, y...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::A system is described that uses an oscillating magnetic field to produce power-frequency electric fields with strengths in excess of those produced in an animal or human standing under a high-voltage electric-power transmission line. In contrast to other types of exposure systems capable of generating fields of this s...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250050202
更新日期:1984-01-01 00:00:00
abstract::In May 2011, the International Agency on Cancer in Research (IARC) issued an official statement concluding that cell phone usage was "possibly carcinogenic to humans." There have been considerable doubts that non-experts and experts alike fully understood what IARC's categorization actually meant, as "possibly carcino...
journal_title:Bioelectromagnetics
pub_type: 信件
doi:10.1002/bem.21851
更新日期:2014-07-01 00:00:00
abstract::We have exposed cultured bone cells to a pulsed electromagnetic field (PEMF) for different times to find the minimal exposure time necessary to stimulate an increase of DNA synthesis. We used two different human osteosarcoma cell lines, TE-85 and MG-63, and human normal osteoblast cell (NHOC) obtained from surgical bo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1999)20:3<177::aid-bem4>3.
更新日期:1999-01-01 00:00:00
abstract::We studied the influence of magnetic fields (MFs) and simulated solar radiation (SSR) on ornithine decarboxylase (ODC) and polyamines in mouse epidermis. Chronic exposure to combined MF and SSR did not cause persistent effects on ODC activity or polyamines compared to the animals exposed only to UV, although the same ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::To assess the effect of a magnetic treatment on pain perception, we compared the sensory threshold in 18 healthy volunteers. We determined the threshold by noninvasive electrical stimulation of the tooth pulp and skin before and after exposure to an altered magnetic field of low intensity and to a sham treatment. Five...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160505
更新日期:1995-01-01 00:00:00
abstract::The US National Electrical Code's (NEC) requirement to ground a home's electrical service to the residential water line results in a voltage between the water line and earth, V W-E. The voltage may result from ground return current that flows into the earth via the water line or from inductive effects from other sourc...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20033
更新日期:2004-10-01 00:00:00
abstract::This study describes the effects of a static magnetic field (SMF) on cell growth and DNA integrity of human umbilical vein endothelial cells (HUVECs). Fast halo assay was used to investigate nuclear damage; quantitative polymerase chain reaction (QPCR), standard PCR, and real-time PCR were used to evaluate mitochondri...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20591
更新日期:2010-12-01 00:00:00
abstract::In this article, the transmembrane voltage induced on erythrocyte, codocyte, ovalocyte and spherocyte cell models exposed to a linearly polarised electromagnetic plane wave of frequency 1800 MHz is calculated. For this purpose, a finite element (FE) numerical technique with adaptive meshing is used. The results show t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20065
更新日期:2004-12-01 00:00:00
abstract::One hundred subjects, males and females with ages ranging between 18 and 48 years, were studied under both field-exposed and sham-exposed conditions. A 50 Hz, 100 mu T magnetic field (MF) was used. To examine the effect of field exposure on performance, a two-alternative, forced-choice, duration-discrimination task wi...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/(SICI)1521-186X(1996)17:2<131::AID-BEM7>3.
更新日期:1996-01-01 00:00:00
abstract::We describe devices designed for magnetic field exposures in which field amplitude and gradients are controlled simultaneously. Dosimetry based on field continuation of high resolution magnetic field scans and numerical models is compared with validation measurements. The dosimetry variables we consider are based on t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20098
更新日期:2005-05-01 00:00:00
abstract::Heat shock proteins (HSPs) are rapidly induced by a variety of stressors, including heat shock, ethanol, heavy metals, UV, and gamma-radiation. Mitogen-activated protein kinases (MAPKs) are also involved in the stress transduction pathways in all eukaryotes. In this study, we attempted to determine whether radiofreque...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20235
更新日期:2006-10-01 00:00:00