Abstract:
:We exposed normal human epidermal keratinocytes to short duration, high frequency, and low amplitude electromagnetic fields, similar to that used by mobile phone technologies. We paid particular attention to the control of the characteristics of the electromagnetic environment generated within a mode stirred reverberation chamber (statistical homogeneity and isotropy of the field and SAR distribution). Two non-thermal exposure conditions were tested on the epidermal cells: 10-min exposure with a field amplitude of 8 V/m, and 30 min with 41 V/m. Corresponding specific absorption rates ranged from 2.6 to 73 mW/kg (continuous wave, 900 MHz carrier frequency). We collected RNA from cells subjected to these conditions and used it for a large-scale microarray screening of over 47000 human genes. Under these conditions, exposure of keratinocytes to the electromagnetic field had little effect; only 20 genes displayed significant modulation. The expression ratios were very small (close to 1.5-fold change), and none of them were shared by the two tested conditions. Furthermore, those assayed using polymerase chain reaction did not display significant expression modulation (overall mean of the exposed samples: 1.20 ± 0.18). In conclusion, the data presented here show that cultured keratinocytes are not significantly affected by EMF exposure.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Roux D,Girard S,Paladian F,Bonnet P,Lalléchère S,Gendraud M,Davies E,Vian Adoi
10.1002/bem.20641subject
Has Abstractpub_date
2011-05-01 00:00:00pages
302-11issue
4eissn
0197-8462issn
1521-186Xjournal_volume
32pub_type
杂志文章abstract::The present study examined the effect on rat cortical synaptosomes of a 2 h exposure to 50-Hz electromagnetic fields (EMFs) with a peak magnetic field of 2 mT. We measured modifications of synaptosomal mitochondrial respiration rate, ATP production, membrane potential, intrasynaptosomal Ca(2+) concentration and free i...
journal_title:Bioelectromagnetics
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abstract::International bodies such as International Commission on Non-Ionizing Radiation Protection (ICNIRP) and the Institute for Electrical and Electronic Engineering (IEEE) make provision for human exposure assessment based on SAR calculations (or measurements) and basic restrictions. In the case of base station exposure th...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-01-01 00:00:00
abstract::We study the effect of microwaves at 2,450 MHz on protein unfolding using surface plasmon resonance sensing. Our experimental method makes use of the fact that unfolding proteins tend to bind to chaperones on their unfolding pathway and this attachment is readily monitored by surface plasmon resonance. We use the prot...
journal_title:Bioelectromagnetics
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abstract::Accumulating evidence does not yet confirm the effect of power line frequency magnetic field (MF) on human health and fertility. We recently reported that, at continuous 60 Hz MF exposure in mice, the dose given as magnetic flux density (tesla; T) and duration of exposure was related to induce testicular germ cell apo...
journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21917
更新日期:2015-07-01 00:00:00
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20416
更新日期:2008-10-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250120106
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21819
更新日期:2014-02-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21730
更新日期:2013-02-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22070
更新日期:2017-12-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1521-186x(1997)18:2<99::aid-bem2>3.0
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160710
更新日期:1995-01-01 00:00:00
abstract::In a previous study, we showed that operators of radiofrequency (RF) plastic sealers, RF operators (n = 35) had a lower heart rate during nighttime compared to a control group (n = 37). We have analyzed the heart rate variability (HRV) on the same group of people to better understand the possible underlying rhythm dis...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20276
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160505
更新日期:1995-01-01 00:00:00
abstract::Laboratory measurements of electric fields have been carried out around examples of smart meter devices used in Great Britain. The aim was to quantify exposure of people to radiofrequency signals emitted from smart meter devices operating at 2.4 GHz, and then to compare this with international (ICNIRP) health-related ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22044
更新日期:2017-05-01 00:00:00
abstract::The stimulatory effects on germination of seeds and growth of plants of static magnetic field (MF) pre-treatments depending on MF intensity, exposure time periods, signal form, flux density, and source frequencies on plants are reported. Seed germination frequency is low due to dormancy in Lathyrus chrysanthus Boiss. ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2018-10-01 00:00:00
abstract::We have previously reported that the exposure to an abnormal magnetic field simulating the one encountered by the International Space Station (ISS) orbiting around the Earth may enhance autonomic response to emotional stimuli. Here we report the results of the second part of that study which tested whether this field ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20438
更新日期:2009-01-01 00:00:00
abstract::In spite of rapid worldwide increase in mobile phone use and public concerns about associated potential health effects, little is known about patterns of mobile phone ownership and use in the general population and among children. In April 2005, we conducted a survey of mobile phone ownership and use among fourth grad...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2007-05-01 00:00:00
abstract::We have shown that 50 Hz sinusoidal magnetic fields within the 5-10 microTesla (microT) rms range cause an intensity-dependent reduction in nerve growth factor (NGF) stimulation of neurite outgrowth (NO) in PC-12 cells. Here we report on the frequency dependence of this response over the 15-70 Hz range at 5 Hz interva...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160607
更新日期:1995-01-01 00:00:00
abstract::To investigate the ability of prokaryotic microorganisms to activate strategies in adapting themselves to the environmental stress induced by exposure to extremely low frequency electromagnetic fields (ELF-EMF), cultures of Escherichia coli ATCC 700926 exposed at 50 Hz EMF (0.1, 0.5, 1.0 mT), and the respective sham-e...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20391
更新日期:2008-05-01 00:00:00
abstract::The impedance spectroscopy technique (IST) was used for studying the effect of a 0.5 T magnetic field on the electrical properties of whole human blood. A Solartron SI 1260 spectrometer was used to measure the impedance spectra of magnetic field exposed blood samples compared to non-exposed samples. An equivalent elec...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20132
更新日期:2005-10-01 00:00:00