Abstract:
:This study was undertaken to investigate whether power frequency magnetic fields can affect the kinetics of cell cycle progression in exposed human cells. To achieve this, cultures of normal human fibroblasts were synchronised in the G(0) phase of the cell cycle and exposed to 50 Hz magnetic fields at a range of flux densities. Progression through the cycle was monitored by examining the timing of entry into S phase, as characterised by the onset of DNA synthesis. Simultaneous positive controls were exposed to human recombinant fibroblast growth factor to demonstrate that the system was responsive to external stimuli. Exposure to magnetic fields at 20 and 200 microT induced a small but significant increase in the length of the G(1) phase of the cell cycle. However, exposure at higher flux densities of 2 and 20 mT had no significant effect. These results are discussed in relation to weak magnetic field effects on free radical concentration.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Cridland NA,Haylock RG,Saunders RDsubject
Has Abstractpub_date
1999-10-01 00:00:00pages
446-52issue
7eissn
0197-8462issn
1521-186Xpii
10.1002/(SICI)1521-186X(199910)20:7<446::AID-BEM6>journal_volume
20pub_type
杂志文章abstract::Adair [Bioelectromagnetics 14:1-4, 1993] writes that "the effects of 60 Hz magnetic fields of 5 microT (50 mG) or less on biological structures holding magnetite (Fe3O4) are shown to be much smaller than those from thermal agitation; hence such interactions cannot be expected to be biologically significant." This conc...
journal_title:Bioelectromagnetics
pub_type: 评论,杂志文章
doi:10.1002/bem.2250150308
更新日期:1994-01-01 00:00:00
abstract::Measurements have been made of vector current densities induced by vertical, uniform, 60-Hz electric fields in the torsos of homogeneous models of swine and rats. The observed data were a strong function of the five grounding configurations invested: all four feet grounded, only front feet grounded, only rear feet gro...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250090102
更新日期:1988-01-01 00:00:00
abstract::The potential effects of radiofrequency (RF) exposure on the genetic material of cells are very important to determine since genome instability of somatic cells may be linked to cancer development. In response to genetic damage, the p53 protein is activated and can induce cell cycle arrest allowing more time for DNA r...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21744
更新日期:2013-01-01 00:00:00
abstract::The use of prosthetic implants is increasing both in the United States and around the world and there is a concomitant rise in cases of biofilm-based, persistent infections that are quite serious and virtually impervious to antibiotic treatment. The development of alternate therapies that do not involve long term use ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20529
更新日期:2010-01-01 00:00:00
abstract::Vertigo-like sensations or apparent perception of movement are reported by some subjects and operators in and around high field whole body magnetic resonance body scanners. Induced currents (which modulate the firing rate of the vestibular hair cell), magneto-hydrodynamics (MDH), and tissue magnetic susceptibility dif...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20316
更新日期:2007-07-01 00:00:00
abstract::The constant exposure of modern society to extremely low frequency magnetic fields (ELF-MF) has raised considerable concerns about the potential risks to male reproduction. However, the epidemiological and experimental data remain contradictory and inconclusive. In the present study, we investigated the effects of 50 ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21816
更新日期:2014-01-01 00:00:00
abstract::Laboratory measurements of electric fields have been carried out around examples of smart meter devices used in Great Britain. The aim was to quantify exposure of people to radiofrequency signals emitted from smart meter devices operating at 2.4 GHz, and then to compare this with international (ICNIRP) health-related ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22044
更新日期:2017-05-01 00:00:00
abstract::This study examined the time dependence effects of exposure to radiofrequency radiation (RFR) emitted by standard GSM cellular phones on the cognitive functions of humans. A total of 48 healthy right-handed male subjects performed a spatial working memory task (that required either a left-hand or a right-hand response...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20458
更新日期:2009-04-01 00:00:00
abstract::Data are presented on ankle-specific SARs and foot currents as a function of strengths of radio-frequency electromagnetic fields encountered by operators of dielectric heaters. The determination of foot currents was based on near-field exposures in which reactive coupling dominates, and which can result in substantial...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130204
更新日期:1992-01-01 00:00:00
abstract::We have shown that 50 Hz sinusoidal magnetic fields within the 5-10 microTesla (microT) rms range cause an intensity-dependent reduction in nerve growth factor (NGF) stimulation of neurite outgrowth (NO) in PC-12 cells. Here we report on the frequency dependence of this response over the 15-70 Hz range at 5 Hz interva...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160607
更新日期:1995-01-01 00:00:00
abstract::The current through the residential grounding circuit is an important source for magnetic fields; field variations near the grounding circuit accurately track fluctuations in this ground current. In this paper, a model is presented which permits calculation of the range of these fluctuations. A discrete network model ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250150109
更新日期:1994-01-01 00:00:00
abstract::We suggest an experimental comparison of two directions for applying the time-varying magnetic fields which have been found to speed spontaneous regeneration of injured peripheral nerves and in attempts to repair spinal cord injuries. Time-varying magnetic fields induce currents in a plane perpendicular to the magneti...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20331
更新日期:2007-09-01 00:00:00
abstract::The treatment of long-term, stable para- and quadriplegics with pulsed electrical stimulation for pain control resulted in, anecdotally, a significant number of these individuals showing increased motor function as well as sensory awareness. This small pilot study was conducted in order to assess the hypothesis that p...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250080206
更新日期:1987-01-01 00:00:00
abstract::There is extensive literature on possible effects of extremely low-frequency magnetic fields (ELF-MFs) on human cognitive functions. However, due to methodological deficits (e.g., low statistical power, small sample sizes) findings have been inconsistent. In the current study we try to overcome these problems by carry...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,meta分析
doi:10.1002/bem.20543
更新日期:2010-04-01 00:00:00
abstract::In this study, we aimed to clarify the effects of chronically applied static magnetic field (200 Gauss) on specific ATPase activities and bioelectrical and biomechanical responses in isolated rat diaphragm muscle. The mean activities of Na(+)-K+ ATPase and Ca2+ ATPase determined from the diaphragm homogenates were sig...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160302
更新日期:1995-01-01 00:00:00
abstract::The clinical and preclinical use of high-field intensity (HF, 3 T and above) magnetic resonance imaging (MRI) scanners have significantly increased in the past few years. However, potential health risks are implied in the MRI and especially HF MRI environment due to high-static magnetic fields, fast gradient magnetic ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20664
更新日期:2011-10-01 00:00:00
abstract::Exposure systems that provide good magnetic field uniformity, minimum stray fields, and minimal heating, vibration, and hum, as well as capability for true sham exposure in which current flows in the coils, are needed to determine rigorously the biological effects of weak magnetic fields. Designs based on acrylic poly...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250150610
更新日期:1994-01-01 00:00:00
abstract::To characterize the inhibitory effect of a static magnetic field, action potentials (AP) were elicited by intracellular application of 1 ms depolarizing current pulses of constant amplitude to the somata of adult mouse dorsal root ganglion neurons in monolayer dissociated cell culture. During the control period, < 5% ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160108
更新日期:1995-01-01 00:00:00
abstract::The influence of a pulsed magnetic field (PMF; sawtooth with 45-microseconds linear rise time and 5-microseconds decay time, peak strength of 15 microT, and frequency 20000 pps) [corrected] on the embryogenesis of CBA/S mice was investigated in five experiments based on a total of 707 exposed and 543 unexposed primigr...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250140303
更新日期:1993-01-01 00:00:00
abstract::The possibility that a sinusoidal 50 Hz magnetic field with a magnetic flux density of 0.5 mT can induce variations in the expression of cell adhesion molecules (CAMs) in two human osteosarcoma cell lines (MG-63 and Saos-2) was investigated. In particular, the expression of two important integrins, VLA-2, the receptor...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10113
更新日期:2003-07-01 00:00:00
abstract::The potential ability of radiofrequency electromagnetic radiation (RFR) in the microwave range to induce mutagenesis, chromosomal aberrations, and sister chromatid exchanges in mammalian cells is being explored in our laboratories. In addition, we have also been examining the ability of simultaneous exposure to RFR an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250110206
更新日期:1990-01-01 00:00:00
abstract::Some epidemiological studies suggest association of childhood cancer with occupational exposure of the parents to magnetic fields. To test this relationship, 50 each of C57BL/6J female and C3H/HeJ male mice were exposed for 2 and 9 weeks, respectively, to 50 Hz sham (group A), 0.5 (group B), and 5 mT (group C) sinusoi...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10012
更新日期:2002-04-01 00:00:00
abstract::To investigate the effects of 1.8 GHz radiofrequency (RF) field on bone microstructure and metabolism of femur in mice, C57BL/6 mice (male, age 4 weeks) were whole-body exposed or sham exposed to 1.8 GHz RF field. Specific absorption rates of whole body and bone were approximately 2.70 and 1.14 W/kg (6 h/day for 28 da...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22125
更新日期:2018-07-01 00:00:00
abstract::Several effects of power-frequency (50/60 Hz) magnetic fields (PF-MF) of weak intensity have been hypothesized in animals and humans. No valid mechanism, however, has been proposed for an interaction between PF-MF and biological tissues and living beings at intensities relevant to animal and human exposure. Here we pr...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20568
更新日期:2010-07-01 00:00:00
abstract::Both positive and negative biological effects of microwaves on drug actions in rats exposed to 1-mW/cm2, 2,450-MHz microwaves have been reported by several investigators. We conducted dosimetry studies for seven different exposure conditions to determine whether these different results could be due to the rats having ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250060108
更新日期:1985-01-01 00:00:00
abstract::Electromagnetic sensibility refers to the ability to perceive the electromagnetic field (EMF) without necessarily developing health symptoms attributed to EMF exposure. A large sample of young healthy adults (n = 84) performed two forced-choice tasks on the perception of the GSM mobile phone EMF (902 MHz pulsed at 217...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20375
更新日期:2008-02-01 00:00:00
abstract::We present a simple readout device that fills the void produced by the gradual disappearance of the Vitck model 101 Electrothermia Monitor. The new device uses commercially available probes that are similar to Bowman's (IEEE Trans Microwave Theory Tech MTT-24:43-45, 1976) original design. As described, the device cove...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250100210
更新日期:1989-01-01 00:00:00
abstract::In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 microTrms/50 Hz did not change nerve growth factor (NGF) induced n...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20073
更新日期:2005-01-01 00:00:00
abstract::Sixty-Hz magnetic field exposures were measured for 45 adult residents of Maine. Thirty of the subjects resided near rights-of-way (ROWs) with either 345- and 115-kV transmission lines, or ROWs with only 115-kV transmission lines; fifteen resided far from any transmission lines. Personal exposure data for a single 24-...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250130106
更新日期:1992-01-01 00:00:00
abstract::The hypogeomagnetic field (HGMF; magnetic fields <200 nT) is one of the fundamental environmental factors of space. However, the effect of HGMF exposure on living systems remains unclear. In this article, we examine the biological effects of HGMF on the embryonic development of Xenopus laevis (African clawed frog). A ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20699
更新日期:2012-04-01 00:00:00