Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation.

Abstract:

:We studied the influence of magnetic fields (MFs) and simulated solar radiation (SSR) on ornithine decarboxylase (ODC) and polyamines in mouse epidermis. Chronic exposure to combined MF and SSR did not cause persistent effects on ODC activity or polyamines compared to the animals exposed only to UV, although the same MF treatment was previously found to accelerate skin tumor development. In an acute 24-h experiment, an elevation of putrescine and down-regulation of ODC activity was observed in the animals exposed to a 100-microT MF. No effect was seen 24 h after a single 2-MED (minimal erythemal dose) exposure to SSR. The results indicate that acute exposure to 50 Hz MF does exert distinctive biological effects on epidermal polyamine synthesis.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Kumlin T,Alhonen L,Jänne J,Lang S,Kosma VM,Juutilainen J

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

388-91

issue

6

eissn

0197-8462

issn

1521-186X

pii

10.1002/(SICI)1521-186X(1998)19:6<388::AID-BEM7>3.

journal_volume

19

pub_type

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