Endogenous ionic currents and DC electric fields in multicellular animal tissues.

Abstract:

:Through the use of the non-invasive vibrating probe technique for detecting extracellular ionic currents developed in 1974 [Jaffe and Nuccitelli: J Cell Biol 63:614-628, 1974], embryonic currents have been detected in a wide range of animal systems (recently reviewed in [Nuccitelli, Noninvasive Techniques in Cell Biology. New York: Wiley-Liss, 1990, pp 273-310]. In four of these studies, the corresponding electric field has been measured within the animal tissue. Such measurements of internal electric fields are quite challenging because they involve the insertion of microelectrodes into the developing tissue along specific regions of current flow. This paper reviews the evidence for endogenous transembryonic currents and dc electric fields in animal systems and provides the range of values for such physiological fields. These data should provide a guide to the range of imposed electric field strengths that could influence normal biological functions in living organisms.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Nuccitelli R

doi

10.1002/bem.2250130714

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

147-57

eissn

0197-8462

issn

1521-186X

journal_volume

Suppl 1

pub_type

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