Hematologic and immunologic effects of pulsed microwaves in mice.


:Mice were exposed in the far field in an anechoic chamber to 2,880-MHz pulsed microwaves 3 to 7.5 h daily, 5 days/week for 60 to 360 h. Three experiments were performed at average power densities of 5 mW/cm2 and six at 10 mW/cm2, corresponding to averaged specific absorption rates (SARs) of 2.25 and 4.50 mW/g, respectively. Each experiment consisted of eight mice, with a concurrently sham-exposed group of eight. In two of three studies at 5 mW/cm2, there was a significant increase in bone marrow cellularity in the microwave-exposed groups compared to the sham-exposed groups. Significant differences were occasionally seen in erythrocyte, leukocyte, and platelet values from microwave-exposed groups, but were not consistently observed. In one of six groups exposed at 10 mW/cm2, mean bone marrow cellularity was reduced significantly in the microwave-exposed mice; in another group, the lymphocyte count was increased. In only one exposure (10 mW/cm2 for 360 h) was any significant effect noted on serum proteins: a reduction to 5.1 +/- 0.3 g/dl in the exposed versus 5.6 +/- 0.4 g/dl in the sham-exposed mice. This was due to a decrease in alpha and beta globulins, with no effect on albumin or gamma globulin concentrations. No effect on bone marrow granulocyte/macrophage colony-forming units (CFU) was revealed following exposure of mice to pulsed microwaves at 5 mW/cm2. In one of four exposures at 10 mW/cm2, there was a significant increase in CFU-agar colonies. No significant effects of exposures at 10 mW/cm2 were observed on in vivo and in vitro assays of cell-mediated immune functions. No exposure-related histopathologic lesions were found from examination of several tissues and organs. Results of these series of exposures of mice at SARs of 2.25 and 4.50 mW/g indicated no consistent effects on the hematologic, immunologic, or histopathologic variables examined.






Ragan HA,Phillips RD,Buschbom RL,Busch RH,Morris JE




Has Abstract


1983-01-01 00:00:00












  • Numerical and analytical methods to determine the current density distributions produced in human and rat models by electric and magnetic fields.

    abstract::Some numerical and analytical methods used to estimate the internal electric fields and current densities produced within human and animal models by low-frequency electric and magnetic fields are surveyed. A major goal of such modeling is the design of laboratory experiments on cellular systems or animal models to pro...


    pub_type: 杂志文章,评审


    authors: Hart FX

    更新日期:1992-01-01 00:00:00

  • Lack of effect of 10 kV/m 60 Hz electric field exposure on pregnant dairy heifer hormones.

    abstract::Sixteen pregnant Holstein heifers weighing 521 +/- 46 kg, at 3.3 +/- 0.7 months of gestation and 2.2 +/- 2.0 months of age were confined to wooden metabolism cages and were exposed to a vertical electric field (EF) of 10.0 +/- 0.4 kV/m and an artificial light cycle of 12 h light-12 h dark. The heifers were divided int...


    pub_type: 杂志文章


    authors: Burchard JF,Nguyen DH,Monardes HG,Petitclerc D

    更新日期:2004-05-01 00:00:00

  • Reactions of keratinocytes to in vitro millimeter wave exposure.

    abstract::The effects of millimeter waves (MW) on human keratinocytes were studied in vitro using the HaCaT keratinocyte cell line. MW-induced modulation of keratinocyte function was studied in proliferation, adhesion, chemotaxis, and interleukin-1beta (IL-1beta) production assays. Spontaneous proliferation, adhesion to tissue ...


    pub_type: 杂志文章


    authors: Szabo I,Rojavin MA,Rogers TJ,Ziskin MC

    更新日期:2001-07-01 00:00:00

  • Chronically indwelling venous cannula and automatic blood sampling system for use with nonhuman primates exposed to 60 Hz electric and magnetic fields.

    abstract::An automated blood sampling system was developed for use with tethered baboons (Papio cynocephalus) during concurrent exposure to 60 Hz 30 kV/m electric fields and 0.1 mT (1.0 G) magnetic fields. The system was controlled by a FORTH-based microcomputer, which operated a pump, a fraction collector, and two pinch valves...


    pub_type: 杂志文章


    authors: Rogers WR,Lucas JH,Mikiten BC,Smith HD,Orr JL

    更新日期:1995-01-01 00:00:00

  • Bacterial response to the exposure of 50 Hz electromagnetic fields.

    abstract::To investigate the ability of prokaryotic microorganisms to activate strategies in adapting themselves to the environmental stress induced by exposure to extremely low frequency electromagnetic fields (ELF-EMF), cultures of Escherichia coli ATCC 700926 exposed at 50 Hz EMF (0.1, 0.5, 1.0 mT), and the respective sham-e...


    pub_type: 杂志文章


    authors: Cellini L,Grande R,Di Campli E,Di Bartolomeo S,Di Giulio M,Robuffo I,Trubiani O,Mariggiò MA

    更新日期:2008-05-01 00:00:00

  • Postmortem changes of the dielectric properties of bovine brain tissues at low radiofrequencies.

    abstract::The dielectric properties of the bovine brain grey and white matter in the frequency range from 20 kHz to 100 MHz were measured at different times following animal death. Changes in the dielectric parameters versus time are interpreted in terms of the reduction of the cell volume fraction that results from either cell...


    pub_type: 杂志文章


    authors: Surowiec A,Stuchly SS,Swarup A

    更新日期:1986-01-01 00:00:00

  • Carcinogenicity test in B6C3F1 mice after parental and prenatal exposure to 50 Hz magnetic fields.

    abstract::Some epidemiological studies suggest association of childhood cancer with occupational exposure of the parents to magnetic fields. To test this relationship, 50 each of C57BL/6J female and C3H/HeJ male mice were exposed for 2 and 9 weeks, respectively, to 50 Hz sham (group A), 0.5 (group B), and 5 mT (group C) sinusoi...


    pub_type: 杂志文章


    authors: Otaka Y,Chida T,Yamagishi Y,Kitamura S

    更新日期:2002-04-01 00:00:00

  • Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT.

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    pub_type: 杂志文章


    authors: Tang R,Xu Y,Ma F,Ren J,Shen S,Du Y,Hou Y,Wang T

    更新日期:2016-02-01 00:00:00

  • Electric field exposure alters serum melatonin but not pineal melatonin synthesis in male rats.

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    pub_type: 杂志文章


    authors: Grota LJ,Reiter RJ,Keng P,Michaelson S

    更新日期:1994-01-01 00:00:00

  • Transmembrane voltage induced on altered erythrocyte shapes exposed to RF fields.

    abstract::In this article, the transmembrane voltage induced on erythrocyte, codocyte, ovalocyte and spherocyte cell models exposed to a linearly polarised electromagnetic plane wave of frequency 1800 MHz is calculated. For this purpose, a finite element (FE) numerical technique with adaptive meshing is used. The results show t...


    pub_type: 杂志文章


    authors: Muñoz S,Sebastián JL,Sancho M,Miranda JM

    更新日期:2004-12-01 00:00:00

  • The effect of 20-week continuous 60 Hz magnetic field exposure on testicular function in sprague-dawley rats.

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    pub_type: 杂志文章


    authors: Park S,Kim YJ,Kim MS,Kim HS,Kim MW,Kang YM,Lee SK,Choi KC,Kim N,Gimm YM,Kim YW

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    pub_type: 杂志文章


    authors: Ptitsyna NG,Villoresi G,Kopytenko YA,Kudrin VA,Tyasto MI,Kopytenko EA,Iucci N,Voronov PM,Zaitsev DB

    更新日期:1996-01-01 00:00:00

  • Thresholds for 60 Hz magnetic field stimulation of peripheral nerves in human subjects.

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    pub_type: 杂志文章


    authors: Bailey WH,Nyenhuis JA

    更新日期:2005-09-01 00:00:00

  • Radiation from mobile phone systems: Is it perceived as a threat to people's health?

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    pub_type: 杂志文章


    authors: Kristiansen IS,Elstein AS,Gyrd-Hansen D,Kildemoes HW,Nielsen JB

    更新日期:2009-07-01 00:00:00

  • Immunological effects of amplitude-modulated radio frequency radiation: B lymphocyte capping.

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    pub_type: 杂志文章


    authors: Sultan MF,Cain CA,Tompkins WA

    更新日期:1983-01-01 00:00:00

  • ELF magnetic fields in electric and gasoline-powered vehicles.

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    pub_type: 杂志文章


    authors: Tell RA,Sias G,Smith J,Sahl J,Kavet R

    更新日期:2013-02-01 00:00:00

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    pub_type: 杂志文章


    authors: Wood AW

    更新日期:2008-09-01 00:00:00

  • Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia: A randomized controlled study.

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    pub_type: 杂志文章,随机对照试验


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    authors: Santini MT,Rainaldi G,Ferrante A,Indovina PL,Vecchia P,Donelli G

    更新日期:2003-07-01 00:00:00

  • No effects of pulsed radio frequency electromagnetic fields on melatonin, cortisol, and selected markers of the immune system in man.

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Radon K,Parera D,Rose DM,Jung D,Vollrath L

    更新日期:2001-05-01 00:00:00

  • Do people understand IARC's 2B categorization of RF fields from cell phones?

    abstract::In May 2011, the International Agency on Cancer in Research (IARC) issued an official statement concluding that cell phone usage was "possibly carcinogenic to humans." There have been considerable doubts that non-experts and experts alike fully understood what IARC's categorization actually meant, as "possibly carcino...


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    authors: Wiedemann PM,Boerner FU,Repacholi MH

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    pub_type: 临床试验,杂志文章,随机对照试验


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    pub_type: 杂志文章


    authors: Dutta SK,Das K,Ghosh B,Blackman CF

    更新日期:1992-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Christ A,Chavannes N,Nikoloski N,Gerber HU,Poković K,Kuster N

    更新日期:2005-02-01 00:00:00

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    pub_type: 杂志文章


    authors: Kowalski T,Silny J,Buchner H

    更新日期:2002-09-01 00:00:00

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    pub_type: 临床试验,杂志文章


    authors: Kyriakou A,Christ A,Neufeld E,Kuster N

    更新日期:2012-07-01 00:00:00

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    pub_type: 杂志文章


    authors: Skyberg K,Hansteen IL,Vistnes AI

    更新日期:2001-04-01 00:00:00

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    pub_type: 杂志文章


    authors: Huang AT,Mold NG

    更新日期:1980-01-01 00:00:00

  • Effects of 1.8 GHz radiofrequency field on microstructure and bone metabolism of femur in mice.

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    pub_type: 杂志文章


    authors: Guo L,Zhang JP,Zhang KY,Wang HB,Wang H,An GZ,Zhou Y,Meng GL,Ding GR

    更新日期:2018-07-01 00:00:00