Effects of ELF magnetic field on membrane protein structure of living HeLa cells studied by Fourier transform infrared spectroscopy.

Abstract:

:The effects of exposure to a 50 Hz magnetic field (maximum of 41.7 to 43.6 mT) on the membrane protein structures of living HeLa cells were studied using attenuated total reflection infrared spectroscopy. One min of such exposure shifted peak absorbance of the amide I band to a smaller wave number, reduced peak absorbance of the amide II band, and increased absorbance at around 1600 cm(-1). These results suggest that exposure to the ELF magnetic field has reversible effects on the N-H inplane bending and C-N stretching vibrations of peptide linkages, and changes the secondary structures of alpha-helix and beta-sheet in cell membrane proteins.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Ikehara T,Yamaguchi H,Hosokawa K,Miyamoto H,Aizawa K

doi

10.1002/bem.10120

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

457-64

issue

7

eissn

0197-8462

issn

1521-186X

journal_volume

24

pub_type

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