Abstract:
:Several investigators have reported robust, statistically significant results that indicate that weak (approximately 1 microT) magnetic fields (MFs) increase the rate of morphological abnormalities in chick embryos. However, other investigators have reported that weak MFs do not appear to affect embryo morphology at all. We present the results of experiments conducted over five years in five distinct campaigns spanning several months each. In four of the campaigns, exposure was to a pulsed magnetic field (PMF); and in the final campaign, exposure was to a 60 Hz sinusoidal magnetic field (MF). A total of over 2500 White Leghorn chick embryos were examined. When the results of the campaigns were analyzed separately, a range of responses was observed. Four campaigns (three PMF campaigns and one 60 Hz campaign) exhibited statistically significant increases (P > or = 0.01), ranging from 2-fold to 7-fold, in the abnormality rate in MF-exposed embryos. In the remaining PMF campaign, there was only a slight (roughly 50%), statistically insignificant (P = 0.2) increase in the abnormality rate due to MF exposure. When the morphological abnormality rate of all of the PMF-exposed embryos was compared to that of all of the corresponding control embryos, a statistically significant (P > or = .001) result was obtained, indicating that PMF exposure approximately doubled the abnormality rate. Like-wise, when the abnormality rate of the sinusoid-exposed embryos was compared to the corresponding control embryos, the abnormality rate was increased (approximately tripled). This robust result indicates that weak EMFs can induce morphological abnormalities in developing chick embryos. We have attempted to analyze some of the confounding factors that may have contributed to the lack of response in one of the campaigns. The genetic composition of the breeding stock was altered by the breeder before the start of the nonresponding campaign. We hypothesize that the genetic composition of the breeding stock determines the susceptibility of any given flock to EMF-induced abnormalities and therefore could represent a confounding factor in studies of EMF-induced bioeffects in chick embryos.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Farrell JM,Litovitz TL,Penafiel M,Montrose CJ,Doinov P,Barber M,Brown KM,Litovitz TAdoi
10.1002/(sici)1521-186x(1997)18:6<431::aid-bem5>3.subject
Has Abstractpub_date
1997-01-01 00:00:00pages
431-8issue
6eissn
0197-8462issn
1521-186Xpii
10.1002/(SICI)1521-186X(1997)18:6<431::AID-BEM5>3.journal_volume
18pub_type
杂志文章abstract::This study aimed to explore effects of static magnetic fields (SMFs) of moderate intensity (3-50 mT) as biophysical stimulators of proliferation and osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells (MSCs). MSCs were exposed to SMFs of three intensities: 3, 15, and 50 mT. Proliferation w...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21903
更新日期:2015-04-01 00:00:00
abstract::Possible effects of 1439 MHz electromagnetic near field (EMF) exposure on the blood-brain barrier (BBB) were investigated using immature (4 weeks old) and young (10 weeks old) rats, equivalent in age to the time when the BBB development is completed and the young adult, respectively. Alteration of BBB related genes, s...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20138
更新日期:2005-10-01 00:00:00
abstract::Serial longitudinal and transverse sections were prepared from roots of Cucumis sativus and Cucurbita maxima that had been exposed/sham-exposed to 60-Hz electric fields for 0-2 days. Field exposures were selected to produce a 10-20% or a 70-80% growth inhibition in whole roots of both species. Cortical cell length and...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250080108
更新日期:1987-01-01 00:00:00
abstract::A number of studies have shown that power frequency magnetic fields may affect spatial memory functions in rodents. An experiment was performed using a spontaneous object recognition task to investigate if nonspatial working memory was similarly affected. Memory changes in adult, male C57BL/6J mice were assessed by me...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/1521-186x(200101)22:1<19::aid-bem3>3.0.co;
更新日期:2001-01-01 00:00:00
abstract::The MobilEe-study was the first cross-sectional population-based study to investigate possible health effects of mobile communication networks on children using personal dosimetry. Exposure was assessed every second resulting in 86,400 measurements over 24 h for each participant. Therefore, a functional approach to an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20477
更新日期:2009-05-01 00:00:00
abstract::The effects of hyperthermia, alone and in conjunction with microwave exposure, on brain energetics were studied in anesthetized male Sprague-Dawley rats. The effect of temperature on adenosine triphosphate concentration [ATP] and creatine phosphate concentration [CP] was determined in the brains of rats that were main...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250050107
更新日期:1984-01-01 00:00:00
abstract::The use of electronic article surveillance (EAS) systems has become popular in many public sites. As a consequence, concern has risen about infant exposure to magnetic fields (MFs) from this kind of device. To evaluate infant exposure to MFs of an EAS system (operating at 125 kHz and 13.56 MHz), we numerically compare...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21901
更新日期:2015-04-01 00:00:00
abstract::In this article, the transmembrane voltage induced on erythrocyte, codocyte, ovalocyte and spherocyte cell models exposed to a linearly polarised electromagnetic plane wave of frequency 1800 MHz is calculated. For this purpose, a finite element (FE) numerical technique with adaptive meshing is used. The results show t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20065
更新日期:2004-12-01 00:00:00
abstract::In the clinic, although several pharmacological agents or surgical procedures are used to treat diabetes and diabetes-induced neuropathic pain, their success has been limited. Therefore, development of different alternatives in treatments is very important. The purpose of this study was to determine the efficacy of pu...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20524
更新日期:2010-01-01 00:00:00
abstract::Both eyes of anesthetized cynomolgus monkeys (Macaca fascicularis) were irradiated with 2.45-GHz microwaves, either pulsed or continuous wave. In vivo corneal endothelial abnormalities were observed by specular microscopy and confirmed through histologic techniques after a 16- to 48-hour postexposure period. Pulsed mi...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250060209
更新日期:1985-01-01 00:00:00
abstract::We developed a new computer wire coding method and then applied it to investigate the suggestion that control selection bias might explain the observed association between wire codes and childhood cancer made in the study conducted by Savitz et al. in the Denver area. The computer wire coding method used a geographic ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::This study was undertaken to investigate whether power frequency magnetic fields can affect the kinetics of cell cycle progression in exposed human cells. To achieve this, cultures of normal human fibroblasts were synchronised in the G(0) phase of the cell cycle and exposed to 50 Hz magnetic fields at a range of flux ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::The clinical and preclinical use of high-field intensity (HF, 3 T and above) magnetic resonance imaging (MRI) scanners have significantly increased in the past few years. However, potential health risks are implied in the MRI and especially HF MRI environment due to high-static magnetic fields, fast gradient magnetic ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20664
更新日期:2011-10-01 00:00:00
abstract::Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were al...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,随机对照试验
doi:10.1002/bem.22127
更新日期:2018-07-01 00:00:00
abstract::We investigated the thermal distribution and cardiovascular effects produced by sustained exposure of rats to 94 GHz radio-frequency electromagnetic radiation (RFR). Sixteen ketamine-anesthetized Sprague-Dawley rats were exposed individually at a power density of 75 mW/cm2 under far-field conditions in E orientation. ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::International bodies such as International Commission on Non-Ionizing Radiation Protection (ICNIRP) and the Institute for Electrical and Electronic Engineering (IEEE) make provision for human exposure assessment based on SAR calculations (or measurements) and basic restrictions. In the case of base station exposure th...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20122
更新日期:2005-09-01 00:00:00
abstract::Vertigo-like sensations or apparent perception of movement are reported by some subjects and operators in and around high field whole body magnetic resonance body scanners. Induced currents (which modulate the firing rate of the vestibular hair cell), magneto-hydrodynamics (MDH), and tissue magnetic susceptibility dif...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20316
更新日期:2007-07-01 00:00:00
abstract::The present article reviews the basic principles of a new approach to the characterization of pulmonary disease. This approach is based on the unique nuclear magnetic resonance (NMR) properties of the lung and combines experimental measurements (using specially developed NMR techniques) with theoretical simulations. T...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1521-186x(1999)20:4+<110::aid-bem13>
更新日期:1999-01-01 00:00:00
abstract::The use of prosthetic implants is increasing both in the United States and around the world and there is a concomitant rise in cases of biofilm-based, persistent infections that are quite serious and virtually impervious to antibiotic treatment. The development of alternate therapies that do not involve long term use ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20529
更新日期:2010-01-01 00:00:00
abstract::To be able to correlate real time membrane potential or ion flux changes with further downstream gene transcription responses due to extremely low frequency (ELF) electromagnetic field (EMF) exposure, we devised an experimental system consisting of a pair of symmetric circular coils. This system can be used on an inve...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.10151
更新日期:2004-01-01 00:00:00
abstract::In a previous investigation we reported that exposure to a moderate (300 mT) static magnetic field (SMF) causes transient DNA damage and promotes mitochondrial biogenesis in human umbilical vein endothelial cells (HUVECs). To better understand the response of HUVECs to the 300 mT SMF, a high-quality subtracted cDNA li...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20686
更新日期:2012-01-01 00:00:00
abstract::We have previously employed the Lorentz-Langevin model to describe the effects of weak exogenous magnetic fields via the classical Lorentz force on a charged ion bound in a harmonic oscillator potential, in the presence of thermal noise forces. Previous analyses predicted that microT-range fields give rise to a rotati...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20494
更新日期:2009-09-01 00:00:00
abstract::The aim of this study was to explore the prevalence, nature and determinants of concerns about mobile phone radiation. We used data from a 2006 telephone survey of 1004 people aged 15+ years in Denmark. Twenty-eight percent of the respondents were concerned about exposure to mobile phone radiation; radiation from mast...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20484
更新日期:2009-07-01 00:00:00
abstract::Exposures to radiofrequency (RF) energy above 6 GHz are characterized by shallow energy penetration, typically limited to the skin, but the subsequent increase in skin temperature is largely determined by heat transport in subcutaneous layers. A detailed analysis of the energy reflection, absorption, and power density...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
doi:10.1002/bem.22110
更新日期:2018-04-01 00:00:00
abstract::For 35 years, I have been involved in various bioelectromagnetics research projects including acute and long-term radiofrequency (RF) bioeffects studies, dosimetry, exposure systems, MRI safety, cancer studies involving hyperthermia and electrochemical treatment, development of RF exposure and measurement standards, a...
journal_title:Bioelectromagnetics
pub_type: 传,历史文章,杂志文章
doi:10.1002/bem.20292
更新日期:2007-01-01 00:00:00
abstract::An experimental arrangement is described that maximized the dosimetric information that can be obtained during in vitro studies with ELF magnetic fields. The arrangement enables researchers to distinguish between a purely magnetic-field effect and one that also involves the electric fields and currents induced by the ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250110306
更新日期:1990-01-01 00:00:00
abstract::The treatment of long-term, stable para- and quadriplegics with pulsed electrical stimulation for pain control resulted in, anecdotally, a significant number of these individuals showing increased motor function as well as sensory awareness. This small pilot study was conducted in order to assess the hypothesis that p...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250080206
更新日期:1987-01-01 00:00:00
abstract::C57/B1 mice were exposed during pregnancy (gestation days 0-19) to a 20 kHz magnetic field (MF). The asymmetric sawtooth-waveform magnetic field in the exposed racks had a flux density of 15 microT (peak to peak). After 19 days, the exposure was terminated, and the mice were housed individually under normal laboratory...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160409
更新日期:1995-01-01 00:00:00
abstract::The effect of millimeter waves (MMWs) on the genome conformational state (GCS) of E. coli AB1157 cells was studied by the method of anomalous viscosity time dependencies (AVTD) in the frequency range of 51.64-51.85 GHz. The 51.755 GHz resonance frequency of the cell reaction to MMWs did not depend on power density (PD...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(SICI)1521-186X(1996)17:4<312::AID-BEM7>3.
更新日期:1996-01-01 00:00:00
abstract::The effects of exposure to clinical magnetic resonance imaging (MRI) on analgesia induced by the mu opiate agonist, fentanyl, was examined in mice. During the dark period, adult male mice were exposed for 23.2 min to the time-varying (0.6 T/sec) magnetic field (TVMF) component of the MRI procedure. Following this expo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250090208
更新日期:1988-01-01 00:00:00