Abstract:
:The mechanism by which animals detect weak electric and magnetic fields has not yet been elucidated. We propose that transduction of an electric field (E) occurs at the apical membrane of a specialized cell as a consequence of an interaction between the field and glycoproteins bound to the gates of ion channels. According to the model, a glycoprotein mass (M) could control the gates of ion channels, where M > 1.4 x 10(-18)/E, resulting in a signal of sufficient strength to overcome thermal noise. Using the electroreceptor organ of Kryptopterus as a mathematical and experimental model, we showed that at the frequency of maximum sensitivity (10 Hz), fields as low as 2 microV/m could be detected, and that the observation could be explained if a glycoprotein mass of 0.7 x 10(-12) kg (a sphere 11 microm in diameter) were bound to channel gates. Antibodies against apical membrane structures in Kryptopterus blocked field transduction, which was consistent with the proposal that it occurred at the membrane surface. Although the target of the field was hypothesized to be an ion channel, the proposed mechanism can easily be extended to include other kinds of membrane proteins.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Kolomytkin OV,Dunn S,Hart FX,Frilot C 2nd,Kolomytkin D,Marino AAdoi
10.1002/bem.20310subject
Has Abstractpub_date
2007-07-01 00:00:00pages
379-85issue
5eissn
0197-8462issn
1521-186Xjournal_volume
28pub_type
杂志文章abstract::For 35 years, I have been involved in various bioelectromagnetics research projects including acute and long-term radiofrequency (RF) bioeffects studies, dosimetry, exposure systems, MRI safety, cancer studies involving hyperthermia and electrochemical treatment, development of RF exposure and measurement standards, a...
journal_title:Bioelectromagnetics
pub_type: 传,历史文章,杂志文章
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abstract::We exposed normal human epidermal keratinocytes to short duration, high frequency, and low amplitude electromagnetic fields, similar to that used by mobile phone technologies. We paid particular attention to the control of the characteristics of the electromagnetic environment generated within a mode stirred reverbera...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
abstract::The current through the residential grounding circuit is an important source for magnetic fields; field variations near the grounding circuit accurately track fluctuations in this ground current. In this paper, a model is presented which permits calculation of the range of these fluctuations. A discrete network model ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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abstract::We have previously reported that the exposure to an abnormal magnetic field simulating the one encountered by the International Space Station (ISS) orbiting around the Earth may enhance autonomic response to emotional stimuli. Here we report the results of the second part of that study which tested whether this field ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20438
更新日期:2009-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章,评审
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更新日期:1989-01-01 00:00:00
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250150610
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2007-07-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 信件
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更新日期:2014-07-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250070105
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20416
更新日期:2008-10-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250150506
更新日期:1994-01-01 00:00:00
abstract::We investigated the effects on human keratinocytes (HaCaT) of exposure to a sinusoidal magnetic field of 2 mT (50 Hz). These cells are a good model for studying interaction of nonionising radiation, because they are not shielded from fields in vivo and also because they are resistant to both mechanical and thermal sti...
journal_title:Bioelectromagnetics
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更新日期:2002-05-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20106
更新日期:2005-09-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250010108
更新日期:1980-01-01 00:00:00
abstract::The use of electronic article surveillance (EAS) systems has become popular in many public sites. As a consequence, concern has risen about infant exposure to magnetic fields (MFs) from this kind of device. To evaluate infant exposure to MFs of an EAS system (operating at 125 kHz and 13.56 MHz), we numerically compare...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21901
更新日期:2015-04-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
abstract::Measurements have been made of vector current densities induced by vertical, uniform, 60-Hz electric fields in the torsos of homogeneous models of swine and rats. The observed data were a strong function of the five grounding configurations invested: all four feet grounded, only front feet grounded, only rear feet gro...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
abstract::The objective of this study was to investigate if persons with implantable medical devices are intrinsically protected by the current electromagnetic safety guidelines. For inter-laboratory comparisons, the U.S. Food and Drug Administration has defined a generic implant as consisting of an insulated wire with noninsul...
journal_title:Bioelectromagnetics
pub_type: 临床试验,杂志文章
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更新日期:2012-07-01 00:00:00
abstract::This study deals with the morphofunctional influence of 72 h exposure to a 6 mT static magnetic field (SMF) during differentiation induced by 50 ng/ml 12-O-tetradecanoyl-13-phorbol acetate (TPA) in human leukaemia U937 cells. The cell morphology of U937 cells was investigated by optic and electron microscopy. Specific...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2009-07-01 00:00:00
abstract::The impedance spectroscopy technique (IST) was used for studying the effect of a 0.5 T magnetic field on the electrical properties of whole human blood. A Solartron SI 1260 spectrometer was used to measure the impedance spectra of magnetic field exposed blood samples compared to non-exposed samples. An equivalent elec...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:2005-10-01 00:00:00
abstract::The potential ability of radiofrequency electromagnetic radiation (RFR) in the microwave range to induce mutagenesis, chromosomal aberrations, and sister chromatid exchanges in mammalian cells is being explored in our laboratories. In addition, we have also been examining the ability of simultaneous exposure to RFR an...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
abstract::This study examined the time dependence effects of exposure to radiofrequency radiation (RFR) emitted by standard GSM cellular phones on the cognitive functions of humans. A total of 48 healthy right-handed male subjects performed a spatial working memory task (that required either a left-hand or a right-hand response...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20458
更新日期:2009-04-01 00:00:00