Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: the value of chromosomal studies in predicting response and survival.

abstract：:The records of 52 patients younger than 40 years of age who had bronchogenic carcinoma diagnosed between 1965 and 1985 were reviewed. The preponderance of adenocarcinoma (54%), the lower male-female ratio in this age group compared with patients age 40 or older (2:1), the importance of cigarette smoking as a causative...

journal_title：Cancer

authors： Jubelirer SJ,Wilson RA

更新日期：1991-03-01 00:00:00

abstract：:A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...

journal_title：Cancer

authors： Wood WC,Kornblith PL,Quindlen EA,Pollock LA

更新日期：1979-01-01 00:00:00

abstract：:Twenty-two cases of breast tumor with infiltrating lobular carcinoma were studied. Thirteen showed the classic single-file pattern as a sole component, and 6 as a predominant pattern; the less common confluent pattern was found in 3 instances as a predominant component. Mucin secretion was evidenced in 59% of the prim...

journal_title：Cancer

authors： Van Bogaert LJ,Maldague P

更新日期：1980-03-01 00:00:00

abstract：:Between 1964 and 1982, 862 patients with acute leukemia who were collected from medical institutions throughout the country had a survival of 5 years or longer. Their remission has been achieved mainly with a combination therapy of vincristine and prednisone in childhood acute leukemia and daunomycin, cytosine arabino...

journal_title：Cancer

authors： Kawashima K,Nagura E,Yamada K,Hamajima N

更新日期：1985-07-01 00:00:00

abstract：:Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...

journal_title：Cancer

authors： Harvey HA,Lipton A,White D,Davidson E

更新日期：1981-01-15 00:00:00

abstract：BACKGROUND:To compare the diagnostic value of thoracoscopic biopsy, fluid cytology, and Abrams needle biopsy, the authors analyzed prospectively the records of 188 patients with malignant pleural mesothelioma examined between 1973 and 1990. Symptoms were pleural effusion in 173 patients, empyema in 1, spontaneous pneum...

journal_title：Cancer

authors： Boutin C,Rey F

更新日期：1993-07-15 00:00:00

abstract：:Adrenal involvement in the course of a non-Hodgkin's lymphoma (NHL) appears to occur relatively often, but only seven cases of NHL-induced adrenal insufficiency were found in a recent review of the literature. The authors report four cases of hypoadrenalism in 127 patients treated for NHL; the cases were staged and cl...

journal_title：Cancer

authors： Gamelin E,Beldent V,Rousselet MC,Rieux D,Rohmer V,Ifrah N,Boasson M,Bigorgne JC

更新日期：1992-05-01 00:00:00

abstract：:Three children with nonlymphoblastic, non-Hodgkin's lymphomas, showed morphologic features that suggested nonlymphoblastic T-cell origin. Tissue for immunologic study was available from two of the three patients; both showed immunophenotypes of T-cells. Although nearly all T-cell lymphomas in children are lymphoblasti...

journal_title：Cancer

authors： Bitter MA,Nachman J,Jones N,Franklin WA,Le Beau MM,Vardiman JW

更新日期：1987-06-15 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：:The long-term cancer specific survival based on individual follow-up and analysis of prospectively collected data from 1061 patients undergoing resection for carcinoma of the rectum is presented. All patients were operated on and managed by one surgeon. Survival data for 978 cases were analyzed according to the method...

journal_title：Cancer

authors： Pihl E,Hughes ES,McDermott FT,Milne BJ,Korner JM,Price AB

更新日期：1980-06-01 00:00:00

abstract：:Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

journal_title：Cancer

authors： Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

更新日期：1980-12-15 00:00:00

abstract：:Androgen deprivation therapy (ADT) is now a well-established standard of care in combination with definitive radiotherapy for patients with unfavorable intermediate-risk to high-risk locally advanced prostate cancer. It is also well established that combination modality treatment with ADT and radiotherapy is superior ...

journal_title：Cancer

authors： Roach M 3rd

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The primary purpose of this study was to establish the maximum tolerated dose (MTD) of intravenous melphalan in combination with paclitaxel and cisplatin plus granulocyte-colony stimulating factor (G-CSF) in patients with suboptimal advanced epithelial ovarian carcinoma or primary peritoneal carcinoma. METH...

journal_title：Cancer

authors： Gershenson DM,Morris M,Burke TW,Levenback C,Wolf J,Lee JJ,Thall PF,Atkinson EN,Silva EG,Wharton JT

更新日期：1999-12-01 00:00:00

abstract：:The predictive value of estrogen receptor (ER) level for response to chemotherapy was studied in 182 patients with metastatic breast cancer in a prospective study. Patients were stratified according to ER status and dominant site of disease and randomized to one of three regimens: cyclophosphamide, 5-Fluorouracil, and...

journal_title：Cancer

authors： Rosner D,Lane WW,Nemoto T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have recently related benzene hexachloride (BHC) to breast carcinoma risk. Experimental studies have also shown that beta-BHC is weakly estrogenic, hence supporting the alleged association. By directly comparing beta-BHC levels in breast adipose tissue from incident breast carcinoma cas...

journal_title：Cancer

authors： Zheng T,Holford TR,Mayne ST,Owens PH,Ward B,Carter D,Dubrow R,Zahm SH,Boyle P,Tessari J

更新日期：1999-05-15 00:00:00

abstract：:Neopterin, a pyrazinopyrimidine compound, is a marker of activation of cell-mediated immunity. Urinary neopterin concentrations were measured in a total of 44 patients with uterine sarcomas. Pretherapeutic neopterin excretions were elevated in 78% (14/18). The mean neopterin concentration of patients with sarcomas was...

journal_title：Cancer

authors： Fuith LC,Fuchs D,Hausen A,Hetzel H,Reibnegger G,Werner ER,Wachter H

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Glioblastoma multiforme (GBM) is the most prevalent and deadly brain tumor. A variety of germline and somatic, genetic and epigenetic alterations at 9p21.3, which encode CDKN2A/CDKN2B tumor suppressor genes, have been isolatedly reported to be associated with GBM risk and prognosis. METHODS:To obtain a comp...

journal_title：Cancer

authors： Feng J,Kim ST,Liu W,Kim JW,Zhang Z,Zhu Y,Berens M,Sun J,Xu J

更新日期：2012-01-01 00:00:00

abstract：:The mitogen-activated protein kinase/extracellular signal-regulated (MAPK/ERK) pathway is activated by upstream genomic events and/or activation of multiple signaling events in which information coalesces at this important nodal pathway point. This pathway is tightly regulated under normal conditions by phosphatases a...

journal_title：Cancer

authors： Burotto M,Chiou VL,Lee JM,Kohn EC

更新日期：2014-11-15 00:00:00

abstract：:Although progress has been made in providing cancer prevention and control services to the population, there remain sizeable segments of the population that are either uninvolved or underinvolved with national and state efforts. One method of reaching most of the population, including those segments currently not invo...

journal_title：Cancer

authors： Iverson DC

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Indium-111 labeled antiferritin targets 95% of all Hodgkin's disease lesions with a diameter of 1 cm or more. Subsequent treatment with yttrium-90 labeled antiferritin secures a high response rate in patients with recurrent Hodgkin's disease. METHODS:A total of 87 patients were entered on one of three diffe...

journal_title：Cancer

authors： Vriesendorp HM,Quadri SM,Andersson BS,Wyllie CT,Dicke KA

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：:Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...

journal_title：Cancer

authors： Bennett JM,Sahasrabudhe DM,Hall WJ

更新日期：1997-10-01 00:00:00

abstract：:Patients with malignant gliomas who had undergone BCG inoculation were injected intratumorally with PPD to induce an intratumoral delayed hypersensitivity reaction. Histopathological examination of the tumor before and after PPD injections revealed that chronic inflammatory responses were increased after injection in ...

journal_title：Cancer

authors： Albright L,Seab JA,Ommaya AK

更新日期：1977-03-01 00:00:00

abstract：:Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

journal_title：Cancer

authors： Gusberg SB

更新日期：1987-10-15 00:00:00

abstract：:On the basis of light microscopic and scanning and transmission ultrastructural observations, we have classified benign mucinous ovarian neoplasms into two types: a pure endocervical type and a mixed intestinal endocervical type. We have also reviewed the literature pertinent to the histogenetic origin of the ovarian ...

journal_title：Cancer

authors： Fenoglio CM,Ferenczy A,Richart RM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Atypical and anaplastic meningiomas tend to recur and to invade adjacent brain, bone, and skin. They also can metastasize to extracranial organs such as the lung, liver, or bone, causing death. Recent reports have indicated that allelic deletion of chromosome 1p is associated with malignant progression of me...

journal_title：Cancer

authors： Ishino S,Hashimoto N,Fushiki S,Date K,Mori T,Fujimoto M,Nakagawa Y,Ueda S,Abe T,Inazawa J

更新日期：1998-07-15 00:00:00

abstract：:A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...

journal_title：Cancer

authors： Salsman JM,Fitchett G,Merluzzi TV,Sherman AC,Park CL

更新日期：2015-11-01 00:00:00

abstract：:The etiology of cancer resembles that of many other diseases in that multiple factors may be required. Because of this, the role or viruses in the etiology of human cancers is especially difficult to assess. When animal tumor systems were used as models, the roles of various predisposing characteristics in virus oncog...

journal_title：Cancer

authors： Rapp F,Reed CL

更新日期：1977-07-01 00:00:00

abstract：:Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

journal_title：Cancer

authors： Marks RD Jr,Wallace KM,Pettit HS

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that the prognosis in patients with extremity soft-tissue sarcomas (ESTS) with isolated lymph node (LN) metastases (stage IV) is comparable to that of patients with high-risk ESTS without metastases (stage III). This study was performed to determine the outcomes of patients wh...

journal_title：Cancer

authors： Al-Refaie WB,Andtbacka RH,Ensor J,Pisters PW,Ellis TL,Shrout A,Hunt KK,Cormier JN,Pollock RE,Feig BW

更新日期：2008-04-15 00:00:00