Immunohistochemical localization of choline acetyltransferase in rabbit forebrain.

Abstract:

:uinea pig antiserum specific to the purified bovine choline acetyltransferase was used to demonstrate the localization of this enzyme in rabbit forebrain by the peroxidase-antiperoxidase immunohistochemical method. Choline acetyltransferase was localized in olfactory bulb, olfactory tract, olfactory tubercle, piriform cortex, septum, diagonal band, basal ganglia, thalamus, hypothalamus, subthalamus, habenula, cerebral cortex, hippocampal region, corpus callosum, internal capsule, fornix, longitudinal striae and other areas. The findings reflect the distribution of cholinergic axons and, possibly, their terminals. These observations correlate well with biochemical determinations of choline acetyltransferase and with previously proposed cholinergic pathways.

journal_name

Brain Res

journal_title

Brain research

authors

Chao LP,Kan KS,Hung FM

doi

10.1016/0006-8993(82)90196-2

subject

Has Abstract

pub_date

1982-03-04 00:00:00

pages

65-82

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(82)90196-2

journal_volume

235

pub_type

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