Target cells for dihydrotestosterone in the guinea pig pituitary gland.

abstract：:To determine whether postmitotic neurons can be immortalized by oncogenic transduction, we used two approaches involving conditional expression of a temperature-sensitive SV40 large T antigen (Tts). Initially, Tts was introduced into E17 rat embryonal hippocampal cells that were then cultured at the non-permissive tem...

journal_title：Brain research

authors： Eves EM,Kwon J,Downen M,Tucker MS,Wainer BH,Rosner MR

更新日期：1994-09-12 00:00:00

abstract：:Glutamate kills sensitive neurons through several steps downstream to receptor activation: increased free Ca2+ levels, activation of various enzymes and accumulation of reactive oxygen species (ROS). We have evaluated in a well established model of neuronal cultures the neuroprotective effects of blocking these mechan...

journal_title：Brain research

authors： Ciani E,Grøneng L,Voltattorni M,Rolseth V,Contestabile A,Paulsen RE

更新日期：1996-07-22 00:00:00

abstract：:The retrograde transport of fluorescent substances was used in order to investigate divergent axon collaterals of neurons in the nucleus prepositus hypoglossi (Ph). Fast blue (FB) was injected into the flocculus, paraflocculus and/or the vermis, while nuclear yellow (NY) was injected into the oculomotor nucleus alone ...

journal_title：Brain research

authors： Yingcharoen K,Rinvik E

更新日期：1982-08-19 00:00:00

abstract：:To elucidate the intracellular mechanism of seizure discharge, phosphorylation of cellular protein during pentylenetetrazole (PTZ)-induced bursting activity in snail neurons was investigated. PTZ markedly enhanced the phosphorylation of proteins of 34,000 and 50,000 molecular weight. Similar effects were observed by a...

journal_title：Brain research

authors： Onozuka M,Imai S,Sugaya E

更新日期：1986-01-01 00:00:00

abstract：:The regulation of corticosteroid receptor expression in the rat brain by adrenal steroids remains controversial. The results of in vivo studies [Brinton and McEwen, 1988; Luttge et al., 1989] suggest that activation of type I receptors can modulate both mineralocorticoid (MR; type I) and glucocorticoid (GR; type II) r...

journal_title：Brain research

authors： O'Donnell D,Meaney MJ

更新日期：1994-02-04 00:00:00

abstract：:In the present study, the role of medial septal receptors in behaviour-induced increase in acetylcholine (ACh) release in hippocampus was investigated using dual-probe microdialysis in combination with a simple behavioural procedure. gamma-Aminobutyric acid (GABA) and glutamate receptor agonists and antagonists were a...

journal_title：Brain research

authors： Moor E,Schirm E,Jacsó J,Westerink BH

更新日期：1998-04-06 00:00:00

abstract：:In a single 10-s training trial, hatchling chicks were conditioned to suppress their spontaneous peck response to a small spherical target by coating it with an aversive liquid. A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior. Leupeptin, a...

journal_title：Brain research

authors： Davis JL,Pico RM

更新日期：1987-03-17 00:00:00

abstract：:Neurotensin (NT) is a neuropeptide neurotransmitter in the central nervous system. It has been implicated in the therapeutic and in the adverse effects of neuroleptics. Activity of NT in brain can only be shown by direct injection of the peptide into that organ. However, we have developed a novel analog of NT(8-13), N...

journal_title：Brain research

authors： Cusack B,Boules M,Tyler BM,Fauq A,McCormick DJ,Richelson E

更新日期：2000-02-21 00:00:00

abstract：:The retinal spreading depression has been used as a tool to investigate the action of nitric oxide (NO) as a diffusible neurotransmitter which in many cases acts by raising the cGMP level in target cells. The role of NO as a vasodilating agents has been well-established and it has been suggested that the vasodilatatio...

journal_title：Brain research

authors： Ulmer HJ,de Lima VM,Hanke W

更新日期：1995-09-11 00:00:00

abstract：:In previous studies we have tested the hypothesis that the termination of the period of sexual behavior in female guinea pigs results from the loss of progestin receptors from hypothalamic cell nuclei. We have shown that hormonal manipulations that delay heat termination also delay loss of hypothalamic nuclear progest...

journal_title：Brain research

authors： Brown TJ,Blaustein JD

更新日期：1986-05-14 00:00:00

abstract：:Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with deficits in fluid reasoning, which may be related to self-regulation of cognition and behavior, and requires intact attention, working memory, and inhibition skills. No functional magnetic resonance imaging (fMRI) studies have directly examined fluid r...

journal_title：Brain research

authors： Tamm L,Juranek J

更新日期：2012-07-17 00:00:00

abstract：:Intracellular recordings were obtained from 212 neurons of the coronal pericruciate cortex of 7 awake, untrained cats. Glass microelectrodes, filled with K+ citrate alone or K+ citrate with either cyclic GMP or 5'-GMP were used for recording and for injecting steady depolarizing and hyperpolarizing currents intracellu...

journal_title：Brain research

authors： Woody CD,Gruen E

更新日期：1978-12-15 00:00:00

abstract：:In our study, we examined middle cerebral artery (MCA) contractile responses in two animal models. After hemorrhagic disturbances in rats of Krushinsky-Molodkina strain (KMRs) a decrease in contractile responses to serotonin (5-HT) was observed. During incomplete global cerebral ischemia, MCAs had increased responsive...

journal_title：Brain research

authors： Fadyukova OE,Storozhevykh TP,Pinelis VG,Koshelev VB

更新日期：2004-01-02 00:00:00

abstract：:Intraocular injections of several different retrograde tracers were made in albino rats. Retrogradely filled neurons were observed in two locations: the medial pretectal area and the contralateral periaqueductal grey matter, indicating that the pretectum and the mesencephalon are sources of centrifugal innervation to ...

journal_title：Brain research

authors： Itaya SK,Itaya PW

更新日期：1985-02-11 00:00:00

abstract：:Work with ion-selective microelectrodes on the retina of the honeybee drone has shown that potassium is released from photoreceptors during activity and enters glial cells. Measurements of the extracellular voltage gradients indicate that, in this preparation, currents flowing through the glial cells in the 'spatial b...

journal_title：Brain research

authors： Gardner-Medwin AR,Coles JA,Tsacopoulos M

更新日期：1981-03-30 00:00:00

abstract：:Recently, a novel method for detection of DNA synthesis has been developed based on the incorporation of 5-ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, into cellular DNA and the subsequent reaction of EdU with a fluorescent azide in a copper-catalyzed [3+2] cycloaddition ("Click" reaction). In the present stud...

journal_title：Brain research

authors： Zeng C,Pan F,Jones LA,Lim MM,Griffin EA,Sheline YI,Mintun MA,Holtzman DM,Mach RH

更新日期：2010-03-10 00:00:00

abstract：:The effects of omega-conotoxin (CTX) GVIA, omega-agatoxin (Aga) IVA, and the dihydropyridine nicardipine were studied on synaptic transmission in the hippocampus during aging. Field excitatory postsynaptic potentials (fEPSPs) were recorded in the CA1 region in slices from young and aged Fischer 344 rats. Peptide toxin...

journal_title：Brain research

authors： Hall SC,Griffith WH

更新日期：1997-01-16 00:00:00

abstract：:Perceptual performance in persons with hearing loss, especially those using devices to restore hearing, is not fully predicted by traditional audiometric measurements designed to evaluate the status of peripheral function. The integrity of auditory brainstem synapses may vary with different forms of hearing loss, and ...

journal_title：Brain research

authors： McGuire B,Fiorillo B,Ryugo DK,Lauer AM

更新日期：2015-04-24 00:00:00

abstract：:The present study investigated the role of calcitonin gene-related peptide (CGRP) on nociception in nucleus raphe magnus (NRM) and the interaction between CGRP and opioid peptides in NRM of rats. CGRP-like immunoreactivity was found at a concentration of 6.0+/-0. 77 pmol/g in NRM tissue of ten samples of rats, suggest...

journal_title：Brain research

authors： Huang Y,Brodda-Jansen G,Lundeberg T,Yu LC

更新日期：2000-08-04 00:00:00

abstract：:The effects of dopamine on glutamate-induced cytotoxicity were examined using the primary cultures of rat striatal neurons. Cell viability was significantly reduced by exposure of cultures to glutamate or kainate for 24 h. In contrast, similar application of N-methyl-D-aspartate (NMDA) or alpha-amino-3-hydroxy-5-methy...

journal_title：Brain research

authors： Amano T,Ujihara H,Matsubayashi H,Sasa M,Yokota T,Tamura Y,Akaike A

更新日期：1994-08-29 00:00:00

abstract：:Highly specific antibodies to dynorphin A(1-13), infused into the lateral ventricle, elevated brain stimulation threshold for eliciting feeding behavior. Antibodies to beta-endorphin had little or no effect. Temporal analysis of the anorectic action indicated a striking similarity to the effect of systemically adminis...

journal_title：Brain research

authors： Carr KD,Bak TH,Gioannini TL,Simon EJ

更新日期：1987-10-06 00:00:00

abstract：:In vivo microdialysis combined with high performance liquid chromatography (HPLC) with electrochemical detection, was used to study the effect of MK-801 (0.1 mg/kg i.p.) on extracellular concentrations of dopamine (DA) 3,4-dihydroxyphenylacetic acid (DOPAC), serotonin (5-HT), norepinephrine (NE) and DOPAC/DA ratio in ...

journal_title：Brain research

authors： Hatip-Al-Khatib I,Mishima K,Iwasaki K,Fujiwara M

更新日期：2001-05-25 00:00:00

abstract：:Ferulic acid (FA) has an important effect on scavenging free radicals, which is related to the alleviation of various neurodegenerative diseases. However, there are few studies about its effects on vascular dementia. In this study, we demonstrated the effect of FA on oxidative damage of brain microvascular endothelial...

journal_title：Brain research

authors： Chen JL,Duan WJ,Luo S,Li S,Ma XH,Hou BN,Cheng SY,Fang SH,Wang Q,Huang SQ,Chen YB

更新日期：2017-07-01 00:00:00

abstract：:The localization of the receptor for apamin, a specific toxin for one class of sensitive Ca2+-dependent K+ channel, was studied in rat brain using an in vitro autoradiographic technique. Radiolabeled monoiodoapamin binds specifically to rat brain sections with a high affinity (Kd = 25 pM) to a single class of sites. A...

journal_title：Brain research

authors： Mourre C,Hugues M,Lazdunski M

更新日期：1986-09-24 00:00:00

abstract：:Kindling is an experimental model for epilepsy in which repeated stimuli induce longer electrographic seizures and eventually cause behavioral convulsions. Although kindling has some features that are similar to chronic human epilepsy, it is not known whether this process plays a role in the development of chronic sei...

journal_title：Brain research

authors： Bertram EH,Cornett J

更新日期：1993-10-22 00:00:00

abstract：:Ultrastructural examination of the region near the olfactory epithelial surface of leopard frogs revealed the presence of nerve terminals just proximal to the zonula adherens between adjacent sustentacular cells, and between sustentacular cells and olfactory receptor neurons. Terminal varicosities, located about 20 nm...

journal_title：Brain research

authors： Zielinski BS,Getchell ML,Getchell TV

更新日期：1989-07-17 00:00:00

abstract：:Two different ligands, tritiated oxytocin and a newly synthesized and monoiodinated oxytocin antagonist, were used to reveal sites which bind oxytocin in the brainstem and upper spinal cord of 12 human subjects. Tissue sections were incubated with either ligand at a concentration close to their respective dissociation...

journal_title：Brain research

authors： Loup F,Tribollet E,Dubois-Dauphin M,Pizzolato G,Dreifuss JJ

更新日期：1989-10-23 00:00:00

abstract：:A procedure has been developed for the stable long-term recording of nerve signals in unanesthetized mammals, which should have wide application in basic research on the nervous system and also in clinical areas such as the derivation of control signals for powered prostheses. Methods are fully described for construct...

journal_title：Brain research

authors： Stein RB,Nichols TR,Jhamandas J,Davis L,Charles D

更新日期：1977-06-03 00:00:00

abstract：:Spontaneous interictal spikes (SISs) were recorded in the hippocampus in freely behaving rats following hippocampal stimulations that resulted in afterdischarges (ADs). Hippocampal SISs were detected after an average of 5 (range 2-10) daily ADs. The rate of SISs typically increased minutes after a tetanus, and then de...

journal_title：Brain research

authors： Leung LW

更新日期：1990-04-16 00:00:00

abstract：:Saccadic adaptation is the progressive correction of systematic saccade targeting errors. When a saccade to a particular target is adapted, saccades within a spatial window around the target, the adaptation field, are affected as a function of their distance from the adapted target. Furthermore, previous studies sugge...

journal_title：Brain research

authors： Collins T,Doré-Mazars K,Lappe M

更新日期：2007-10-03 00:00:00