Dual effect of calmidazolium (R 24571) on transmitter release at the frog neuromuscular junction.

abstract：:The S allele of serotonin transporter gene (5-HTTLPR) has been found to increase the risk of depression and other mental health problems, but some evidence suggests that S-allele carriers outperform subjects carrying the long allele in an array of cognitive tasks. Evidence linking this polymorphism with individual var...

journal_title：Brain research

authors： Proshina EA,Savostyanov AN,Bocharov AV,Knyazev GG

更新日期：2018-10-15 00:00:00

abstract：:The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...

journal_title：Brain research

authors： Rigaud AS,Pinard E,Borredon J,Seylaz J

更新日期：1990-11-05 00:00:00

abstract：:The localization of immunoreactive glutamic acid decarboxylase (GAD) and enkephalin-like immunoreactivity was examined in serial, 4-micron frozen sections of the caudate nucleus from rats pretreated with colchicine. Colocalization was found in numerous caudate neurons of medium size. Cell counts of corresponding label...

journal_title：Brain research

authors： Aronin N,Difiglia M,Graveland GA,Schwartz WJ,Wu JY

更新日期：1984-05-23 00:00:00

abstract：:Small iontophoretic application of wheat-germ-agglutinin conjugated to horseradish peroxidase, was used to simultaneously observe, in the rat, the afferent and the efferent connections of the cuneiformis nucleus (Cnf), in the same animal. The results demonstrate that the main Cnf afferent connections originate from: (...

journal_title：Brain research

authors： Bernard JF,Peschanski M,Besson JM

更新日期：1989-06-19 00:00:00

abstract：:Using the acetylthiocholine staining method, it was possible to visualize acetylcholinesterase (AChE)-stained neuronal cell bodies and nerve endings as well as AChE-positive vesicles in the rat duodenum. AChE-reactive perikarya were seen with certainty only in the myenteric plexus. They were 40 micron in diameter and ...

journal_title：Brain research

authors： Wolter HJ

更新日期：1985-07-29 00:00:00

abstract：:We have identified an inhibitory neuron (RPL4) in the right pleural ganglion of Aplysia, which produced hyperpolarization of the sensory and motor neurons involved in the tail withdrawal reflex. Activation of RPL4 significantly reduced the amplitude of excitatory postsynaptic potentials produced in tail motor neurons ...

journal_title：Brain research

authors： Buonomano DV,Cleary LJ,Byrne JH

更新日期：1992-04-10 00:00:00

abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...

journal_title：Brain research

authors： Foley TD,Rhoads DE

更新日期：1994-08-08 00:00:00

abstract：:Quantitative morphological techniques have revealed several new aspects of the action of the Staggerer mutant gene. Staggerer is an autosomal recessive gene which causes ataxia and severe malformation of the cerebellar cortex in mice. The Purkinje cells of the cerebellar cortex are small, abnormal in morphology and re...

journal_title：Brain research

authors： Roffler-Tarlov S,Herrup K

更新日期：1981-06-29 00:00:00

abstract：:The response properties of neurons in the region of striate cortex subserving central retina (0 degrees-2 degrees) and in a region of representation of parafoveal retina (4 degrees-7 degrees) were studied in unanesthetized paralyzed macaque monkeys. Neurons sensitive to the orientation of the stimulus in the visual fi...

journal_title：Brain research

authors： Poggio GF,Baker FH,Mansfield RJ,Sillito A,Grigg P

更新日期：1975-12-12 00:00:00

abstract：:We have previously shown that hypothyroidism produces a decrease in the number of spines counted along the apical shafts of pyramidal neurons of the cortex. Nevertheless, other authors have found that when an animal is subjected to some adverse living conditions the size of the spines decreases, making them invisible ...

journal_title：Brain research

authors： Berbel PJ,Escobar del Rey F,Morreale de Escobar G,Ruiz-Marcos A

更新日期：1985-07-01 00:00:00

abstract：:The role of plantar pressure sensation in controlling compensatory stepping was explored via hypothermic anesthesia of the foot soles, in 10 healthy young adults. Stepping reactions were evoked by unpredictable platform translation in forward, backward and lateral directions. The findings suggest three specific direct...

journal_title：Brain research

authors： Perry SD,McIlroy WE,Maki BE

更新日期：2000-09-22 00:00:00

abstract：:Horseradish peroxidase (HRP, 30% solution, 0.1-0.3 mul, 72 h) was injected unilaterally into the basal striatum (STR) and the dorsal ventricular ridge (DVR) of adult turtles (Chrysemys picta) in order to demonstrate the cells of origin of some afferents to these telencephalic structures. After selective STR injection,...

journal_title：Brain research

authors： Parent A

更新日期：1976-05-21 00:00:00

abstract：:The extrafusal and intrafusal muscle fibers in the masseter muscle are innervated by motoneurons in the trigeminal motor nucleus (Mo 5). In the present study, we found that the number of trigeminal motor neurons in the male mouse was significantly larger than that in the female. However, we could not detect any signif...

journal_title：Brain research

authors： Maeda N,Sugiyama H,Suemune S,Wakisaka H,Niida S,Ogata K,Miyata K

更新日期：1993-11-05 00:00:00

abstract：:We used amygdala-kindled seizures in rats to study the function of striatal gamma-aminobutyrate (GABA) in the regulation of the seizure threshold of the limbic forebrain. Microinjections of the GABAA antagonist, bicuculline methiodide, 1 pmol, into the caudate-putamen protected rats against amygdala-kindled seizures. ...

journal_title：Brain research

authors： Cavalheiro EA,Bortolotto ZA,Turski L

更新日期：1987-05-19 00:00:00

abstract：:Cerebellar granule neuronal cultures have been used to study the molecular mechanisms underlying neuronal functions, including neuronal morphogenesis. However, a limitation of this system is the difficulty to analyze isolated neurons because these are required to be maintained at a high density. Therefore, in the pres...

journal_title：Brain research

authors： Kubota K,Seno T,Konishi Y

更新日期：2013-11-20 00:00:00

abstract：:Histone proteins from purified nuclei of neonatal and adult mouse retinas were analyzed and compared utilizing SDS-polyacrylamide gel electrophoresis. Identical procedures were applied to examine the histones extracted from the brains of the same animals. In the newborn and mature retina and brain, 8 histone fractions...

journal_title：Brain research

authors： Perkins PS,Young RW

更新日期：1987-06-01 00:00:00

abstract：:Tourette syndrome (TS) is a childhood-onset tic disorder associated with abnormal development of brain networks involved in the sensory and motor processing. An involvement of immune mechanisms in its pathophysiology has been proposed. Animal models based on active immunization with bacterial or viral mimics, direct i...

journal_title：Brain research

authors： Martino D,Zis P,Buttiglione M

更新日期：2015-08-18 00:00:00

abstract：:This review examines vestibular compensation and vestibular rehabilitation from a unified translational research perspective. Laboratory studies illustrate neurobiological principles of vestibular compensation at the molecular, cellular and systems levels in animal models that inform vestibular rehabilitation practice...

journal_title：Brain research

authors： Balaban CD,Hoffer ME,Gottshall KR

更新日期：2012-10-30 00:00:00

abstract：:Cholinergic mechanisms in the septohippocampal pathway contribute to several cognitive functions and impaired cholinergic transmission in this pathway may be related to the memory loss and dementia that accompanies normal aging and Alzheimer's disease and behavioral studies suggest that muscarinic mechanisms in the me...

journal_title：Brain research

authors： Liu W,Kumar A,Alreja M

更新日期：1998-09-14 00:00:00

abstract：:Several forebrain areas have been shown to project to the parabrachial nucleus (PBN) and exert inhibitory and excitatory influences on taste processing. The neurochemicals by which descending forebrain inputs modulate neural taste-evoked responses remain to be established. This study investigated the existence of soma...

journal_title：Brain research

authors： Panguluri S,Saggu S,Lundy R

更新日期：2009-11-17 00:00:00

abstract：:Recent studies have shown that moving in synchrony with auditory stimuli boosts attention allocation and verbal learning. Furthermore rhythmic tones are processed more efficiently than temporally random tones ('timing effect'), and this effect is increased when participants actively synchronize their motor performance...

journal_title：Brain research

authors： Schmidt-Kassow M,Thöne K,Kaiser J

更新日期：2019-08-01 00:00:00

abstract：:Glucagon like peptide-1 (7-36) amide (GLP-1), a potent regulator of glucose homeostasis, is also produced in the central nervous system and has been implicated in the control of hypothalamic-pituitary function and food intake. GLP-1 immunoreactive (IR) fibers and terminals are widely distributed in the septum, hypotha...

journal_title：Brain research

authors： Sarkar S,Fekete C,Légrádi G,Lechan RM

更新日期：2003-09-26 00:00:00

abstract：:The effects of systemically administered interleukin-1beta (1.0 microg) on in vivo variations of monoamines was assessed in several brain regions. Administration of the cytokine provoked a modest increase of extracellular 5-HIAA and HVA from the nucleus accumbens, and 5-HIAA from the hippocampus. Following mild neurog...

journal_title：Brain research

authors： Merali Z,Lacosta S,Anisman H

更新日期：1997-07-04 00:00:00

abstract：:MPTP is a neurotoxin thought to damage dopaminergic neurons through free radical formation. MPTP is metabolized in the brain to MPP(+), which is taken up into dopaminergic neurons via the dopamine transporter and assumed to impair mitochondrial function. We used striatal synaptosomes and telencephalic mitochondria to ...

journal_title：Brain research

authors： Fonck C,Baudry M

更新日期：2003-06-13 00:00:00

abstract：:The firing patterns of up to 4 concurrently active masseter motor units were studied with intramuscular electrodes during a continuous isometric contraction of 15 min duration, in which the subject maintained the mean firing rate of one selected unit at 10 Hz. With this paradigm the net excitation (i.e. mean firing ra...

journal_title：Brain research

authors： Nordstrom MA,Miles TS

更新日期：1991-05-24 00:00:00

abstract：:We assessed the application of a replication deficient recombinant adenovirus vector as a retrograde tracer in neural pathway studies. The adenovirus vector, Ad. RSV betagal, containing the intracellular marker gene, beta-galactosidase, was injected directly into the laterodorsal striatum of rats. The retrograde trans...

journal_title：Brain research

authors： Kuo H,Ingram DK,Crystal RG,Mastrangeli A

更新日期：1995-12-24 00:00:00

abstract：:Mouse brain was found by immunoblot analysis to have a protein of Mr 23,000 (P23k) that was clearly different from recoverin and was labeled with an antiserum raised against the NH2-terminus of recoverin. P23k could not be detected by an antiserum raised against the COOH-terminus of recoverin. Blots with 45Ca demonstr...

journal_title：Brain research

authors： Takamatsu K,Uyemura K

更新日期：1992-02-07 00:00:00

abstract：:To determine whether postmitotic neurons can be immortalized by oncogenic transduction, we used two approaches involving conditional expression of a temperature-sensitive SV40 large T antigen (Tts). Initially, Tts was introduced into E17 rat embryonal hippocampal cells that were then cultured at the non-permissive tem...

journal_title：Brain research

authors： Eves EM,Kwon J,Downen M,Tucker MS,Wainer BH,Rosner MR

更新日期：1994-09-12 00:00:00

abstract：:Studies of the subcellular localization of neuroreceptors in the rat brain have shown that most of them are associated with light and low density subcellular fractions. In two human brain areas, quite different subcellular distributions were observed. After fractionation by differential centrifugation of frontal corte...

journal_title：Brain research

authors： Maloteaux JM,Luabeya MK,Vanisberg MA,Jeanjean AP,Baudhuin P,Scherman D,Laduron PM

更新日期：1995-07-31 00:00:00

abstract：:Using a double-labelling procedure, morphological relationships existing between dopaminergic and indoleaminergic neuronal systems in the rat brain were investigated. First, thanks to a tryptamine (T) antiserum, we visualized this indoleamine in all mesencephalic regions and showed that the T-immunoreactivity (IR) see...

journal_title：Brain research

authors： Dabadie H,Mons N,Geffard M

更新日期：1990-03-26 00:00:00