Abstract：
:Using the acetylthiocholine staining method, it was possible to visualize acetylcholinesterase (AChE)-stained neuronal cell bodies and nerve endings as well as AChE-positive vesicles in the rat duodenum. AChE-reactive perikarya were seen with certainty only in the myenteric plexus. They were 40 micron in diameter and were mostly localized in groups within the ganglia (3-6 neurons per ganglion). Some thick, AChE-reactive nerve processes, running over a long distance in interconnecting nerve fibre strands, had their origin from AChE-containing myenteric plexus perikarya. AChE-stained nerve fibres were detected in the myenteric and submucosal plexus as well as in the longitudinal and circular smooth muscle cell layer. AChE-positive nerve fibres were in close contacts with blood vessels, probably arterioles, Brunner's gland cells and epithelial cells. A conspicuously high density of AChE-positive nerve fibres was noted in the longitudinal smooth muscle layer, while AChE-stained nerve fibres were visualized only sporadically in the circular smooth muscle layer. Some Brunner's gland cells and epithelial cells contained AChE-reactive vesicles, which were constantly localized on the basal cell portion. The present findings might indicate that acetylcholine possesses important physiological roles as neurotransmitter and/or neuromodulator in the rat duodenum.
journal_name
Brain Resjournal_title
Brain researchauthors
Wolter HJdoi
10.1016/0006-8993(85)90100-3subject
Has Abstractpub_date
1985-07-29 00:00:00pages
337-41issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(85)90100-3journal_volume
339pub_type
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