Polyurethane shape-memory polymers demonstrate functional biocompatibility in vitro.

abstract：:"Three-layered micelles" (3LM) composed of two triblock copolymers, poly(L-lactide)-b-polyethyleneimine-b-poly(L-lactide) (PLLA-PEI-PLLA) and poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) (PLLA-PEG-PLLA) are designed to combine electrostatic interaction and solvent-induced condensation of DNA. The low mole...

journal_title：Macromolecular bioscience

authors： Abebe DG,Kandil R,Kraus T,Elsayed M,Merkel OM,Fujiwara T

更新日期：2015-05-01 00:00:00

abstract：:A ternary complex comprising plasmid DNA, lipopolysaccharide-binding peptide (LBP), and deoxycholic acid-conjugated polyethylenimine (PEI-DA) is prepared for combinational therapy of acute lung injury (ALI). The LBP is designed as an anti-inflammatory peptide based on the lipopolysaccharide (LPS)-binding domain of HMG...

journal_title：Macromolecular bioscience

authors： Kim JY,Piao C,Kim G,Lee S,Lee MS,Jeong JH,Lee M

更新日期：2017-08-01 00:00:00

abstract：:Photo-crosslinkable, fumaric acid monoethyl ester-functionalized triblock oligomers are synthesized and copolymerized with N-vinyl-2-pyrrolidone to form biodegradable photo-crosslinked hydrogels. Poly(ethylene glycol) is used as the middle hydrophilic segment and the hydrophobic segments are based on D,L-lactide, trim...

journal_title：Macromolecular bioscience

authors： Jansen J,Mihov G,Feijen J,Grijpma DW

更新日期：2012-05-01 00:00:00

abstract：:Herein, a new series of non-ionic dendritic and carbohydrate based amphiphiles is synthesized employing biocompatible starting materials and studied for supramolecular aggregate formation in aqueous solution. The dendritic amphiphiles 12 and 13 possessing poly(glycerol) [G2.0] as hydrophilic unit and C-10 and C-18 hyd...

journal_title：Macromolecular bioscience

authors： Prasad S,Achazi K,Schade B,Haag R,Sharma SK

更新日期：2018-07-01 00:00:00

abstract：:In this work we report, compare and discuss the results obtained from fully atomistic molecular dynamics simulations of generations 4, 5, and 6 of PAMAM-based dendrimers having NH(3) and triethanolamine as cores, forming complexes with a short interfering RNA (siRNA) at different pH values and at physiological ionic ...

journal_title：Macromolecular bioscience

authors： Karatasos K,Posocco P,Laurini E,Pricl S

更新日期：2012-02-01 00:00:00

abstract：:Microbial transglutaminase (mTG) and mushroom tyrosinase (MT) are used to crosslink B. mori silk fibroin/gelatin (SF/G) films. Crosslinked and uncrosslinked SF/G films show no phase separation. The thermal behavior and the conformational structure of SF/G films are strongly affected by blending and enzymatic treatment...

journal_title：Macromolecular bioscience

authors： Taddei P,Chiono V,Anghileri A,Vozzi G,Freddi G,Ciardelli G

更新日期：2013-11-01 00:00:00

abstract：:The supramolecular self-assembly of macromonomers may serve as a first step to prepare well-defined, highly functionalized, hierarchically structured, conjugated polymers. Functional diacetylene macromonomers equipped with an oligopeptide segment designed to promote self-assembly into parallel beta-sheet type structur...

journal_title：Macromolecular bioscience

authors： Jahnke E,Millerioux AS,Severin N,Rabe JP,Frauenrath H

更新日期：2007-02-12 00:00:00

abstract：:Functional hydrophilic microspheres (latex particles) have found various applications in life sciences and in medicine - particularly in latex diagnostic tests. This paper presents a comprehensive review of studies on latex particles with a hydrophilic interfacial layer composed of various hydrophilic polymers with re...

journal_title：Macromolecular bioscience

authors： Basinska T

更新日期：2005-12-15 00:00:00

abstract：:The present study describes the synthesis of novel polypeptides containing O-phospho-L-threonine [Thr(PO(3)H(2))] and L-aspartic acid. Random copolypeptides copoly[Thr(PO(3)H(2))(X)Asp(Y)] (X:Y = 25:75, 50:50, 75:25), were conventionally prepared by copolymerization of Thr(PO(3)Ph(2)) N-carboxyanhydride (NCA) and Asp(...

journal_title：Macromolecular bioscience

authors： Hayashi S,Ohkawa K,Yamamoto H

更新日期：2006-03-14 00:00:00

abstract：:Three types of multilayer films made from poly(L-lysine)/hyaluronan, chitosan/hyaluronan, and poly(allylamine hydrochloride)/poly(L-glutamic acid), were used to investigate the interplay between film mechano-chemical properties and cell adhesion. We showed that C2C12 myoblast adhesion and proliferation depended on the...

journal_title：Macromolecular bioscience

authors： Boudou T,Crouzier T,Nicolas C,Ren K,Picart C

更新日期：2011-01-10 00:00:00

abstract：:Diblock and multiblock copolymers composed of a poly(D,L-lactide) (PLA) or poly(trimethylene carbonate) (PTMC) core with a hydrophilic chain of poly(ethylene glycol) (PEG) were prepared. These copolymers, in which the core is connected to PEG through a polyfunctional molecule such as citric, mucic, or tartaric acid, m...

journal_title：Macromolecular bioscience

authors： Ben-Shabat S,Kumar N,Domb AJ

更新日期：2006-12-08 00:00:00

abstract：:Chitin is the second most abundant natural polysaccharide with biocompatibility and bioactivity. Aqueous KOH/urea solution is reported for rapid dissolution of chitin, therefore providing a greener and more efficient avenue to fabricate chitin-based functional materials. Chitosan is the most important derivative of ch...

journal_title：Macromolecular bioscience

authors： Xu H,Zhang L,Zhang H,Luo J,Gao X

更新日期：2021-01-18 00:00:00

abstract：:Peptide dendrimers assembled by solid-phase peptide synthesis using a branching diamino acid at every 2(nd) or 3(rd) position provide readily accessible synthetic model systems for proteins and enzymes. They adopt a globular shape by topology rather than by folding. Peptide dendrimers of 2(nd) and 3(rd) generation fun...

journal_title：Macromolecular bioscience

authors： Delort E,Szöcs E,Widmer R,Siegenthaler H,Reymond JL

更新日期：2007-08-07 00:00:00

abstract：:Novel temperature-sensitive poly(N-isopropylacrylamide)/amine-terminated polyamidoamine dendrimer G6-NH2 hydrogels with fast responsive properties were synthesized by forming semi-interpenetrating polymeric networks. In contrast to the conventional PNIPA hydrogel, these new gels showed rapid shrinking rate at the temp...

journal_title：Macromolecular bioscience

authors： Zhang JT,Huang SW,Zhuo RX

更新日期：2004-06-25 00:00:00

abstract：:We present a two-fold study designed to elucidate the adhesion mechanism of human U937 monocytes on novel N-rich thin films deposited by plasma- and VUV photo-polymerisation, so-called "PVP:N" materials. It is shown that there exist sharply-defined ("critical") surface-chemical conditions that are necessary to induce ...

journal_title：Macromolecular bioscience

authors： Girard-Lauriault PL,Truica-Marasescu F,Petit A,Wang HT,Desjardins P,Antoniou J,Mwale F,Wertheimer MR

更新日期：2009-09-09 00:00:00

abstract：:Two different composite scaffolds, solid-freeform-fabricated PCL/β-TCP supplemented with and without collagen nanofibers are fabricated. These scaffolds are evaluated whether a combination of collagen nanofibers with PCL/β-TCP can promote osteogenesis in a mastoid obliteration. To assess the effects of the cellular ac...

journal_title：Macromolecular bioscience

authors： Jang CH,Cho YB,Yeo MG,Kim GH

更新日期：2013-05-01 00:00:00

abstract：:Polymers such as poly(N-vinyl-2-pyrrolidone) (PVP) have been used to prepare hydrogels for wound dressing applications but are not inherently bioactive. For enhanced healing, PVP was blended with salicylic acid-based poly(anhydride-esters) (SAPAE) and shown to exhibit hydrogel properties upon swelling. In vitro releas...

journal_title：Macromolecular bioscience

authors： Ouimet MA,Fogaça R,Snyder SS,Sathaye S,Catalani LH,Pochan DJ,Uhrich KE

更新日期：2015-03-01 00:00:00

abstract：:Multicellular tumor spheroid (MCTS) mimics microenvironment for tumor formation and provides predictive insight for in vivo tests. The hanging drop (HD) method of spheroid generation is cost effective, but it is limited by a long time duration for spheroid development and a low rate of formation of larger spheroids. T...

journal_title：Macromolecular bioscience

authors： R A V,Kumari S,Poddar P,Dhara D,Maiti S

更新日期：2020-08-01 00:00:00

abstract：:O-carboxymethylchitin (molecular weight = 1.07 x 10(5), degree of carboxymethylation = 80%, degree of N-acetylation = 91%) was chemically attached to superoxide dismutase by the formation of amide linkages through a carbodiimide catalyzed reaction. The glycosidated enzyme contained about 1.8 mole of polysaccharide per...

journal_title：Macromolecular bioscience

authors： Valdivia A,Perez Y,Dominguez A,Caballero J,Gomez L,Schacht EH,Villalonga R

更新日期：2005-02-23 00:00:00

abstract：:A novel PEGylated biodegradable hyperbranched PEG-b-PDMAEMA has been synthesized. The low toxicity, small molecular weight PDMAEMA chains were crosslinked using a biodegradable disulfide-based dimethacrylate (DSDMA) agent to yield higher molecular weight hyperbranched polymers. PEG chains were linked onto the polymer ...

journal_title：Macromolecular bioscience

authors： Tao L,Chou WC,Tan BH,Davis TP

更新日期：2010-06-11 00:00:00

abstract：:Currently, there is no gadolinium-based contrast agent available for conventional magnetic resonance imaging (MRI) detection of amyloidal beta (Aβ) plaques in Alzheimer's disease (AD). Its timely finding would be vital for patient survival and quality of life. Curcumin (CUR), a common Indian spice effectively binds to...

journal_title：Macromolecular bioscience

authors： Patil R,Gangalum PR,Wagner S,Portilla-Arias J,Ding H,Rekechenetskiy A,Konda B,Inoue S,Black KL,Ljubimova JY,Holler E

更新日期：2015-09-01 00:00:00

abstract：:The naturally occurring edible biopolymer poly(gamma-glutamic acid) (gamma-PGA) is shown to be an efficient chelating agent of vanadium(IV). The structure of poly(gamma-glutamic acid)oxovanadium(IV) (VO-gamma-PGA) complex in solution has been analyzed by electron spin resonance and UV-visible absorption spectra. The e...

journal_title：Macromolecular bioscience

authors： Karmaker S,Saha TK

更新日期：2008-02-11 00:00:00

abstract：:An electroactive amino/carboxyl-capped aniline tetramer (AT) is covalently grafted to the surface of hydroxyapatite (HA) nanoparticles to generate novel electroactive HA-AT nanoparticles. The amount of AT ranges from 16.5 to 34.0 wt% and is characterized by thermogravimetric analysis (TGA). The HA-AT nanoparticles are...

journal_title：Macromolecular bioscience

authors： Liu Y,Cui H,Zhuang X,Zhang P,Cui Y,Wang X,Wei Y,Chen X

更新日期：2013-03-01 00:00:00

abstract：:Metastasis is a pathogenic spread of cancer cells from the primary site to surrounding tissues and distant organs, making it one of the primary challenges for effective cancer treatment and the major cause of cancer mortality. Heparin-based biomaterials exhibit significant inhibition of cancer cell metastasis. In this...

journal_title：Macromolecular bioscience

authors： Andrgie AT,Mekuria SL,Addisu KD,Hailemeskel BZ,Hsu WH,Tsai HC,Lai JY

更新日期：2019-05-01 00:00:00

abstract：:Plant derived flavonoids have not been well explored in tissue engineering applications due to difficulties in efficient formulations with biomaterials for controlled presentation. Here, the authors report that surface coating of epigallocatechin gallate (EGCG) on polymeric substrates including poly (L-lactic acid) (P...

journal_title：Macromolecular bioscience

authors： Madhurakkat Perikamana SK,Lee SM,Lee J,Ahmad T,Lee MS,Yang HS,Shin H

更新日期：2019-04-01 00:00:00

abstract：:A HBSP has been designed as a novel bifunctional enzyme model with SOD and GPx activity by host/guest-directed self-assembly of MnTPyP-M-Ad and 6-Te-diCD. The structure of the host/guest complex was elucidated by (1) H NMR spectra, and the HBSP was characterized by SEM, DLS and measurement of catalytic properties. In ...

journal_title：Macromolecular bioscience

authors： Yu S,Zhang W,Zhu J,Yin Y,Jin H,Zhou L,Luo Q,Xu J,Liu J

更新日期：2011-06-14 00:00:00

abstract：:It is of paramount importance to study the cellular uptake processes of particles with defined surface property, especially the uptake pathways and intracellular transportation. In this study, aptamer AS1411 molecules, which are known to specifically bind the over-expressed nucleolin on cancer cell membrane, were conj...

journal_title：Macromolecular bioscience

authors： Yu D,Zhang Y,Mao Z,Gao C

更新日期：2013-10-01 00:00:00

abstract：:Polylaminin (polyLM) is a polymerized form of the extracellular matrix protein laminin obtained upon pH acidification. Here microscopy and spectroscopic tools are used to study the cell compatibility and the structural stability of polyLM, aiming at establishing its robustness as a biopolymer for therapeutic use. Poly...

journal_title：Macromolecular bioscience

authors： Freire E,Barroso MM,Klier RN,Coelho-Sampaio T

更新日期：2012-01-01 00:00:00

abstract：:The use of glycopolymer-functionalized resins (Resin-Glc), as a solid support, in column mode for bacterial/protein capture and quantification is explored. The Resin-Glc is synthesized from commercially available chloromethylated polystyrene resin and glycopolymer, and is characterized by fourier transform infrared sp...

journal_title：Macromolecular bioscience

authors： Ajish JK,Abraham HM,Subramanian M,Kumar KSA

更新日期：2020-12-18 00:00:00

abstract：:In this preliminary work we have prepared a fluorinated polymer capable of solubilizing an appreciable amount of O(2) and, at the same time, maintaining a higher water solubility than perfluoroalkanes investigated as injectable O(2) carriers. In particular, we describe the synthesis and characterization of a new macro...

journal_title：Macromolecular bioscience

authors： Mandracchia D,Piccionello AP,Pitarresi G,Pace A,Buscemi S,Giammona G

更新日期：2007-06-07 00:00:00