Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease.

abstract：:Formulation of docetaxel (DOC), a hydrophobic anticancer drug, was successfully achieved in poly(gamma-benzyl L-glutamate)-block-hyaluronan polymersomes using a simple and reproducible nanoprecipitation method. The prepared DOC loaded polymersomes (PolyDOC) was stable either in solution or in a lyophilized form, and s...

journal_title：Macromolecular bioscience

authors： Upadhyay KK,Bhatt AN,Castro E,Mishra AK,Chuttani K,Dwarakanath BS,Schatz C,Le Meins JF,Misra A,Lecommandoux S

更新日期：2010-05-14 00:00:00

abstract：:Vascular grafts are used to bypass damaged or diseased blood vessels. Bacterial cellulose (BC) has been studied for use as an off-the-shelf graft. Herein, we present a novel, cost-effective, method for the production of small caliber BC grafts with minimal processing or requirements. The morphology of the graft wall p...

journal_title：Macromolecular bioscience

authors： Leitão AF,Faria MA,Faustino AM,Moreira R,Mela P,Loureiro L,Silva I,Gama M

更新日期：2016-01-01 00:00:00

abstract：:Microbubbles (MB) are routinely used as contrast agents for ultrasound (US) imaging. In recent years, MB have also attracted interest as drug delivery systems. Soft-shelled lipidic MB tend to be more advantageous for US imaging, while hard-shelled polymeric MB appear to be more suitable for drug delivery purposes beca...

journal_title：Macromolecular bioscience

authors： Appold L,Shi Y,Rütten S,Kühne A,Pich A,Kiessling F,Lammers T

更新日期：2017-10-01 00:00:00

abstract：:Transparent, biodegradable, mechanically robust, and surface-patterned silk films were evaluated for the effect of surface morphology on human corneal fibroblast (hCF) cell proliferation, orientation, and ECM deposition and alignment. A series of dimensionally different surface groove patterns were prepared from optic...

journal_title：Macromolecular bioscience

authors： Gil ES,Park SH,Marchant J,Omenetto F,Kaplan DL

更新日期：2010-06-11 00:00:00

abstract：:Tissue damage caused by excessive amounts of neutrophil-derived reactive oxygen species (ROS) occurs in many inflammatory diseases. Butyrate is a short-chain fatty acid (SCFA) with known anti-inflammatory properties, able to modulate several neutrophil functions. Evidence is provided here that butyrate inhibits neutro...

journal_title：Macromolecular bioscience

authors： Sacco P,Decleva E,Tentor F,Menegazzi R,Borgogna M,Paoletti S,Kristiansen KA,Vårum KM,Marsich E

更新日期：2017-11-01 00:00:00

abstract：:3D hydrogels better replicate in vivo conditions, and yield different results from 2D substrates. However, imaging interactions between cells and the hydrogel microenvironment is challenging because of light diffraction and poor focal depth. Here, cryosectioning and vibrating microtomy methods and fixation protocols a...

journal_title：Macromolecular bioscience

authors： Short AR,Czeisler C,Stocker B,Cole S,Otero JJ,Winter JO

更新日期：2017-06-01 00:00:00

abstract：:Aggregation is frequently encountered during coating nanoparticles, especially when the core is not solid and the coating polyelectrolytes are weak. Here, the coating of a nanoliposome with two weak polyelectrolytes, alginate and chitosan, is investigated. First, quartz crystal microbalance with dissipation, atomic fo...

journal_title：Macromolecular bioscience

authors： Nayef L,Castiello R,Tabrizian M

更新日期：2017-06-01 00:00:00

abstract：:Plant derived flavonoids have not been well explored in tissue engineering applications due to difficulties in efficient formulations with biomaterials for controlled presentation. Here, the authors report that surface coating of epigallocatechin gallate (EGCG) on polymeric substrates including poly (L-lactic acid) (P...

journal_title：Macromolecular bioscience

authors： Madhurakkat Perikamana SK,Lee SM,Lee J,Ahmad T,Lee MS,Yang HS,Shin H

更新日期：2019-04-01 00:00:00

abstract：:A gold standard for esophagus reconstruction is not still available. The present work aims to design a polymer patch combining synthetic polylactide-co-polycaprolacton and chitosan biopolymers, tailoring patch properties to esophageal tissue characteristics by a temperature-induced precipitation method, to get multila...

journal_title：Macromolecular bioscience

authors： Dorati R,De Trizio A,Marconi S,Ferrara A,Auricchio F,Genta I,Modena T,Benazzo M,Benazzo A,Volpato G,Conti B

更新日期：2017-06-01 00:00:00

abstract：:Polycations, mimicking activity of antibacterial peptides, belong to an important class of molecules investigated as a support or as an alternative to antibiotics. In this work, studies of modified linear amphiphilic statistical polymethyloxazoline (PMOX) and polyethyleneimine copolymers (PMOX_PEI) series are presente...

journal_title：Macromolecular bioscience

authors： Kozon D,Mierzejewska J,Kobiela T,Grochowska A,Dudnyk K,Głogowska A,Sobiepanek A,Kuźmińska A,Ciach T,Augustynowicz-Kopeć E,Jańczewski D

更新日期：2019-12-01 00:00:00

abstract：:To explore the potential of a star-shaped 8-armed poly(ethylene glycol)35K-block-poly(L-lactide)37K (8-armed PEG35K-b-PLLA37K: M(n) of PEG = 35 000, M(n) of PLLA = 37 000) film as a novel bioabsorbable adhesion-prevention membrane, the water structure, surface contact angle, protein adsorption, and cell and platelet a...

journal_title：Macromolecular bioscience

authors： Nagahama K,Ohya Y,Ouchi T

更新日期：2006-06-16 00:00:00

abstract：:The antimicrobial activity of poly(alkyloxazoline) telechelics with one quaternary N,N-dimethyldodecylammonium (DDA) end group was found to be greatly controlled by the non-bioactive distal end group, the so-called satellite group. In systematic investigations, the nature of the latter groups was varied to explore the...

journal_title：Macromolecular bioscience

authors： Waschinski CJ,Herdes V,Schueler F,Tiller JC

更新日期：2005-02-23 00:00:00

abstract：:Two chondrogenic factors, Dex and TGF-beta1, were incorporated into PLGA scaffolds and their chondrogenic potential was evaluated. The Dex-loaded PLGA scaffold was grafted with AA and heparin, the heparin-immobilized one was then reacted with TGF-beta1, yielding a PLGA/Dex-TGF (PLGA/D/T) scaffold. The scaffolds were s...

journal_title：Macromolecular bioscience

authors： Park K,Cho KJ,Kim JJ,Kim IH,Han DK

更新日期：2009-03-10 00:00:00

abstract：:In situ self-assemblies of new biodegradable triblock PLLA-b-PBS-b-PLLA and PDLA-b-PBS-b-PDLA have been investigated in acetonitrile solution. At first, two series of PLLA-b-PBS-b-PLLA and PDLA-b-PBS-b-PDLA, respectively denoted as the P and Q triblock copolyester series, were prepared with fixed PBS block ((overline)...

journal_title：Macromolecular bioscience

authors： Jia L,Yin L,Li Y,Li Q,Yang J,Yu J,Shi Z,Fang Q,Cao A

更新日期：2005-06-24 00:00:00

abstract：:Molecularly imprinted polymers (MIPs) are synthetic affinity matrices capable of selective binding a specific target molecule. A strategy for competitive selectivity studies is developed providing information on the selective binding properties of MIPs in complex matrices. Batch rebinding experiments entail the target...

journal_title：Macromolecular bioscience

authors： Pluhar B,Mizaikoff B

更新日期：2015-11-01 00:00:00

abstract：:A poly(o-methoxyaniline) (POMA)/DNA [weight fraction of DNA (W(DNA)) = 0.45] hybrid was prepared by mixing their solutions in sterilized double distilled water. The solution turned green upon aging for a longer time, and the doping of POMA by DNA was complete after about 15 d of aging. The doping was confirmed from th...

journal_title：Macromolecular bioscience

authors： Dawn A,Nandi AK

更新日期：2005-05-23 00:00:00

abstract：:The immobilization of enzymes into polymer hydrogels is a versatile approach to improve their stability and utility in biotechnological and biomedical applications. However, these systems typically show limited enzyme activity, due to unfavorable pore dimensions and low enzyme accessibility. Here, 3D jet writing of wa...

journal_title：Macromolecular bioscience

authors： Steier A,Schmieg B,Irtel von Brenndorff Y,Meier M,Nirschl H,Franzreb M,Lahann J

更新日期：2020-09-01 00:00:00

abstract：:The use of glycopolymer-functionalized resins (Resin-Glc), as a solid support, in column mode for bacterial/protein capture and quantification is explored. The Resin-Glc is synthesized from commercially available chloromethylated polystyrene resin and glycopolymer, and is characterized by fourier transform infrared sp...

journal_title：Macromolecular bioscience

authors： Ajish JK,Abraham HM,Subramanian M,Kumar KSA

更新日期：2020-12-18 00:00:00

abstract：:The enzymatic transformation into an oligomer was carried out with the objective of developing the chemical recycling of bacterial polyesters. Poly(R-3-hydroxyalkanoate)s (PHAs), such as poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyhexanoate)] and poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyvalerate)], were degraded ...

journal_title：Macromolecular bioscience

authors： Kaihara S,Osanai Y,Nishikawa K,Toshima K,Doi Y,Matsumura S

更新日期：2005-07-14 00:00:00

abstract：:A nanoformulation composed of curdlan, a linear polysaccharide of 1,3-β-linked d-glucose units, hydrogen bonded to poly(γ -glutamic acid) (PGA), was developed to stimulate macrophage. Curdlan/PGA nanoparticles (C-NP) are formulated by physically blending curdlan (0.2 mg mL-1 in 0.4 m NaOH) with PGA (0.8 mg mL-1 ). For...

journal_title：Macromolecular bioscience

authors： Heo J,Sobiech TA,Kutscher HL,Chaves L,Sukumaran DK,Karki S,Dube A,Prasad PN,Reynolds JL

更新日期：2021-01-01 00:00:00

abstract：:Thermosensitive polymers enable externally controllable biomolecular interactions but hysteresis effects hamper the reversibility and repeated use of these materials. To quantify the temperature-dependent interactions and hysteresis effects, an optical adhesion assay based on poly(ethylene glycol) microgels (soft coll...

journal_title：Macromolecular bioscience

authors： Strzelczyk AK,Paul TJ,Schmidt S

更新日期：2020-10-01 00:00:00

abstract：:Diblock and multiblock copolymers composed of a poly(D,L-lactide) (PLA) or poly(trimethylene carbonate) (PTMC) core with a hydrophilic chain of poly(ethylene glycol) (PEG) were prepared. These copolymers, in which the core is connected to PEG through a polyfunctional molecule such as citric, mucic, or tartaric acid, m...

journal_title：Macromolecular bioscience

authors： Ben-Shabat S,Kumar N,Domb AJ

更新日期：2006-12-08 00:00:00

abstract：:An insoluble wheat proteins-based polymer networks with new functional groups and positive charges were prepared through grafting-coupling reactions. The networks were also flexible with a lower glass transition temperature since the existence of the grafted mobile segments. The multi-component/multi-phase systems bec...

journal_title：Macromolecular bioscience

authors： Kurniawan L,Qiao GG,Zhang X

更新日期：2009-01-09 00:00:00

abstract：:The next-generation sutures should provide in situ monitoring of wound condition such as temperature while reducing surgical site infection during wound closure. In this study, functionalized nanodiamond (FND) and reduced graphene oxide (rGO) into biodegradable polycaprolactone (PCL) are incorporated to develop a new ...

journal_title：Macromolecular bioscience

authors： Houshyar S,Bhattacharyya A,Khalid A,Rifai A,Dekiwadia C,Kumar GS,Tran PA,Fox K

更新日期：2021-01-12 00:00:00

abstract：:We report on a novel series of biomimetic polymers exhibiting interfacial properties similar to the extracellular matrix. A series of well-defined surfactant polymers were synthesized by simultaneously incorporating arginine-glycine-aspartic acid (RGD) peptide, dextran oligosaccharide, and hexyl ligands with controlle...

journal_title：Macromolecular bioscience

authors： Anderson EH,Ruegsegger MA,Murugesan G,Kottke-Marchant K,Marchant RE

更新日期：2004-08-09 00:00:00

abstract：:Pedobacter sp. KP-2 can degrade and metabolize thermally synthesized alpha,beta-poly(D,L-aspartic acid) (tPAA), which contains 70% of unnatural beta-amide units, with high-molecular-weight. In this study, gene cloning and molecular characterization of PAA hydrolase-1 from KP-2 was carried out. Gene analysis reveals th...

journal_title：Macromolecular bioscience

authors： Hiraishi T,Masuda E,Kanayama N,Nagata M,Doi Y,Abe H,Maeda M

更新日期：2009-01-09 00:00:00

abstract：:The fabrication of 3D cell microenvironments exploiting versatile, long-term stable passivating poly(acryl amide) brushes in a microwell format and the study of the behavior of fibroblast and pancreatic tumor cells in wells of systematically varied shape and size is reported. The microwells, which are obtained by comb...

journal_title：Macromolecular bioscience

authors： Lilge I,Jiang S,Schönherr H

更新日期：2017-05-01 00:00:00

abstract：:Poly[(R)-3-hydroxybutyrate] (P(3HB)) and its copolymers are accumulated by a wide variety of microorganisms as intracellular carbon and energy material, and are extensively studied as biodegradable and biocompatible thermoplastics. However, these microbial polyesters have not been recognized as practical because of th...

journal_title：Macromolecular bioscience

authors： Iwata T

更新日期：2005-08-12 00:00:00

abstract：:Novel molecular ecological techniques were used to study changes in microbial community structure and population during degradation of polylactide (PLA)/organically modified layered silicates (OMLS) nanocomposites. Cloned gene sequences belonging to members of the phyla Actinobacteria and Ascomycota comprized the most...

journal_title：Macromolecular bioscience

authors： Sangwan P,Way C,Wu DY

更新日期：2009-07-07 00:00:00

abstract：:In this work, it is first reported that the poly (3-hydroxybutyric acid) (PHB) oligomer with a few degrees of polymerization possesses effective antibacterial and antifungal properties. Two preparation methods for the PHB oligomer are described, namely, one-step ring-opening polymerization of β-butyrolactone and extra...

journal_title：Macromolecular bioscience

authors： Ma L,Zhang Z,Li J,Yang X,Fei B,Leung PHM,Tao X

更新日期：2019-05-01 00:00:00