Long-Term Stable Poly(acrylamide) Brush Modified Transparent Microwells for Cell Attachment Studies in 3D.

abstract：:In this report, we developed a simple and green process of simultaneous formation of doxorubicin-BSA-dextran nanoparticles in aqueous solution and high-effective encapsulation of doxorubicin. In the presence of BSA-dextran conjugates, which were produced by Maillard reaction, a binding of doxorubicin with BSA can supp...

journal_title：Macromolecular bioscience

authors： Deng W,Li J,Yao P,He F,Huang C

更新日期：2010-10-08 00:00:00

abstract：:Intrinsic antimicrobial thermoplastic A(BC)n copolymers (n = 1, 2, 4), where A was poly(ethylene glycol) (PEG), BC was a random chain of methylmethacrylate (MMA), and alkyl-aminoethyl methacrylate (AAEMA), were synthesized and the antimicrobial activity and hemolyticity were evaluated on plaques obtained by casting as...

journal_title：Macromolecular bioscience

authors： Matrella S,Vitiello C,Mella M,Vigliotta G,Izzo L

更新日期：2015-07-01 00:00:00

abstract：:A novel elastic scaffold that simulates the deformability of annulus fibrosus (AF) and has good biocompatibility was developed. The scaffold was formed of a malic acid-based polyester poly(1,8-octanediol malate) (POM), which was synthesized by direct polycondensation. The tensile strength of POM gradually increased wi...

journal_title：Macromolecular bioscience

authors： Wan Y,Feng G,Shen FH,Balian G,Laurencin CT,Li X

更新日期：2007-11-12 00:00:00

abstract：:A hybrid system for producing conducting polymers within a doping hydrogel mesh is presented. These conductive hydrogels demonstrate comparable electroactivity to conventional conducting polymers without requiring the need for mobile doping ions which are typically used in literature. These hybrids have superior mecha...

journal_title：Macromolecular bioscience

authors： Green RA,Hassarati RT,Goding JA,Baek S,Lovell NH,Martens PJ,Poole-Warren LA

更新日期：2012-04-01 00:00:00

abstract：:Open-pore biodegradable foams with controlled porous architectures were prepared by combining gas foaming and microparticulate templating. Microparticulate composites of poly(epsilon-caprolactone) (PCL) and micrometric sodium chloride particles (NaCl), in concentrations ranging from 70/30 to 20/80 wt.-% of PCL/NaCl we...

journal_title：Macromolecular bioscience

authors： Salerno A,Iannace S,Netti PA

更新日期：2008-07-07 00:00:00

abstract：:New nonfouling tubes are developed and their influence on the adhesion of neuroproteins is studied. The biomarkers are considered as single components (recombinant prion and Tau proteins) or in a solution of native and pathological forms. The samples are stored for 24 h at 4 °C in virgin and treated tubes layered with...

journal_title：Macromolecular bioscience

authors： Vrlinic T,Debarnot D,Legeay G,Coudreuse A,El Moualij B,Zorzi W,Perret-Liaudet A,Quadrio I,Mozetic M,Poncin-Epaillard F

更新日期：2012-10-01 00:00:00

abstract：:Cell-free approaches to in situ tissue engineering require materials that are mechanically stable and are able to control cell-adhesive behavior upon implantation. Here, the development of mechanically stable grafts with non-cell adhesive properties via a mix-and-match approach using ureido-pyrimidinone (UPy)-modified...

journal_title：Macromolecular bioscience

authors： van Almen GC,Talacua H,Ippel BD,Mollet BB,Ramaekers M,Simonet M,Smits AI,Bouten CV,Kluin J,Dankers PY

更新日期：2016-03-01 00:00:00

abstract：:In this work, it is first reported that the poly (3-hydroxybutyric acid) (PHB) oligomer with a few degrees of polymerization possesses effective antibacterial and antifungal properties. Two preparation methods for the PHB oligomer are described, namely, one-step ring-opening polymerization of β-butyrolactone and extra...

journal_title：Macromolecular bioscience

authors： Ma L,Zhang Z,Li J,Yang X,Fei B,Leung PHM,Tao X

更新日期：2019-05-01 00:00:00

abstract：:Chitosan is non-toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofibrous materials is ...

journal_title：Macromolecular bioscience

authors： Ignatova M,Manolova N,Rashkov I

更新日期：2013-07-01 00:00:00

abstract：:Microbial transglutaminase (mTG) and mushroom tyrosinase (MT) are used to crosslink B. mori silk fibroin/gelatin (SF/G) films. Crosslinked and uncrosslinked SF/G films show no phase separation. The thermal behavior and the conformational structure of SF/G films are strongly affected by blending and enzymatic treatment...

journal_title：Macromolecular bioscience

authors： Taddei P,Chiono V,Anghileri A,Vozzi G,Freddi G,Ciardelli G

更新日期：2013-11-01 00:00:00

abstract：:Recently, the Foresight Institute has pronounced six economic challenges that can be addressed through the progress of nanotechnology. One of these is the health and longevity of human life. Amongst applications anticipated to provide a solution to this challenge, gene therapy appears to be particularly promising. In ...

journal_title：Macromolecular bioscience

authors： Lamarre B,Ryadnov MG

更新日期：2011-04-08 00:00:00

abstract：:The use of long-lasting polymer coatings on biodevice surfaces has been investigated to improve material-tissue interaction, minimize adverse effects, and enhance their functionality. Natural polymers, especially chitosan, are of particular interest due to their excellent biological properties, such as biocompatibilit...

journal_title：Macromolecular bioscience

authors： Souza Campelo C,Chevallier P,Loy C,Silveira Vieira R,Mantovani D

更新日期：2020-01-01 00:00:00

abstract：:5,6-Bis(benzylideneamino)-2-mercaptopyrimidin-4-ol (SCR7) is a new anti cancer molecule having capability to selectively inhibit non-homologous end joining (NHEJ), one of the DNA double strand break (DSB) repair pathways inside the cells. In spite of the promising potential as an anticancer agent, hydrophobicity of SC...

journal_title：Macromolecular bioscience

authors： John F,George J,Vartak SV,Srivastava M,Hassan PA,Aswal VK,Karki SS,Raghavan SC

更新日期：2015-04-01 00:00:00

abstract：:3D printing has become an essential part of bone tissue engineering and attracts great attention for the fabrication of bioactive scaffolds. Combining this rapid manufacturing technique with chemical precipitation, biodegradable 3D scaffold composed of polymer matrix (polylactic acid and polyethylene glycol), ceramics...

journal_title：Macromolecular bioscience

authors： Li X,Wang Y,Wang Z,Qi Y,Li L,Zhang P,Chen X,Huang Y

更新日期：2018-06-01 00:00:00

abstract：:The synthesis of a new glycomonomer based on mannose, prepared via CuAAC, is reported. The resulting 1,2,3-triazole linkage between mannose and the polymer backbone ensures the formation of highly stable glycopolymers, which will not undergo hydrolysis. The monomer 2'-(4-vinyl-[1,2,3]-triazol-1-yl)ethyl-O-alpha-D-mann...

journal_title：Macromolecular bioscience

authors： Hetzer M,Chen G,Barner-Kowollik C,Stenzel MH

更新日期：2010-02-11 00:00:00

abstract：:The random copolymer, poly[lactide-co-glycotide-co-(epsilon-caprolactone)] (PLGACL) diacrylate was prepared by ring-opening polymerization of L-lactide, glycolide, and epsilon-caprolactone initiated with tetra(ethylene glycol). The diacrylated polymers were extensively characterized. With a UV embossing method, these ...

journal_title：Macromolecular bioscience

authors： Zhu A,Chen R,Chan-Park MB

更新日期：2006-01-05 00:00:00

abstract：:The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus des...

journal_title：Macromolecular bioscience

authors： Mackie AR,Goycoolea FM,Menchicchi B,Caramella CM,Saporito F,Lee S,Stephansen K,Chronakis IS,Hiorth M,Adamczak M,Waldner M,Nielsen HM,Marcelloni L

更新日期：2017-08-01 00:00:00

abstract：:The effect of doping graphene oxide (GO) and reduced graphene oxide (rGO) into poly(ε-caprolactone) (PCL) membranes prepared by solvent induced phase separation is evaluated in terms of nanomaterial distribution and compatibility with neural stem cell growth and functional differentiation. Raman spectra analyses demon...

journal_title：Macromolecular bioscience

authors： Sánchez-González S,Diban N,Bianchi F,Ye H,Urtiaga A

更新日期：2018-11-01 00:00:00

abstract：:Mesenchymal stem cells (MSC), also called marrow stromal cells, are adult cells that have attracted interest for their potential uses in therapeutic applications. There is a pressing need for scalable culture systems due to the large number of cells needed for clinical treatments. Here, a tailorable thin polymer coati...

journal_title：Macromolecular bioscience

authors： Krutty JD,Dias AD,Yun J,Murphy WL,Gopalan P

更新日期：2019-02-01 00:00:00

abstract：:Photo-crosslinking and self-healing have received considerable attention for the design of intelligent materials. A novel photostimulated, self-healing, and cytocompatible hydrogel system is reported. A coumarin methacrylate crosslinker is synthesized to modify the polyacrylamide-based hydrogels. With the [2+2] cyclo-...

journal_title：Macromolecular bioscience

authors： Yu L,Xu K,Ge L,Wan W,Darabi A,Xing M,Zhong W

更新日期：2016-09-01 00:00:00

abstract：:Previously synthesized amphiphilic diblock copolymers with pendant dendron moieties have been investigated for their potential use as drug carriers to improve the delivery of an anticancer drug to human breast cancer cells. Diblock copolymer (P71 D3 )-based micelles effectively encapsulate the doxorubicin (DOX) with a...

journal_title：Macromolecular bioscience

authors： Viswanathan G,Hsu YH,Voon SH,Imae T,Siriviriyanun A,Lee HB,Kiew LV,Chung LY,Yusa S

更新日期：2016-06-01 00:00:00

abstract：:A gold standard for esophagus reconstruction is not still available. The present work aims to design a polymer patch combining synthetic polylactide-co-polycaprolacton and chitosan biopolymers, tailoring patch properties to esophageal tissue characteristics by a temperature-induced precipitation method, to get multila...

journal_title：Macromolecular bioscience

authors： Dorati R,De Trizio A,Marconi S,Ferrara A,Auricchio F,Genta I,Modena T,Benazzo M,Benazzo A,Volpato G,Conti B

更新日期：2017-06-01 00:00:00

abstract：:Current approaches to generate core-shell nanoparticles for biomedical applications are limited by factors such as synthetic scalability and circulatory desorption of cytotoxic surfactants. Developments in controlled radical polymerization, particularly in dispersed states, represent a promising method of overcoming t...

journal_title：Macromolecular bioscience

authors： Gurnani P,Sanchez-Cano C,Abraham K,Xandri-Monje H,Cook AB,Hartlieb M,Lévi F,Dallmann R,Perrier S

更新日期：2018-10-01 00:00:00

abstract：:Novel water-insoluble, and reduction-responsive nonwoven scaffolds were fabricated from gamma-PGA and tested in cell culture. An electrospinning method was developed to produce scaffolds of fibers with diameters of 0.05-0.5 microm. Crosslinking of the fibers with cystamine in the presence of EDC resulted in water-inso...

journal_title：Macromolecular bioscience

authors： Yoshida H,Klinkhammer K,Matsusaki M,Möller M,Klee D,Akashi M

更新日期：2009-06-11 00:00:00

abstract：:A generally applicable strategy to obtain mechanically robust hydrogels for the incorporation and containment of functional reporter bacteria for the microarray and microparticle-based detection and signaling of N-acyl homoserine lactone autoinducers (3OC12 HSL) at relevant concentrations is reported. For reinforcing ...

journal_title：Macromolecular bioscience

authors： Li P,Dou X,Müller M,Feng C,Chang MW,Frettlöh M,Schönherr H

更新日期：2017-11-01 00:00:00

abstract：:Controlled delivery of multiple growth factors (GFs) holds great potential for the clinical treatment of ischemic diseases and might be more therapeutically effective to reestablish vasculature than the provision of a single GF. Vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) are two poten...

journal_title：Macromolecular bioscience

authors： Awada HK,Johnson NR,Wang Y

更新日期：2014-05-01 00:00:00

abstract：:Tissue adhesives are an attractive class of biomaterials, which can serve as a treatment for meniscus tears. In this study, physicochemical and adhesive properties of novel biodegradable three-armed- and hyperbranched block copolymeric adhesives are evaluated. Additionally, their degradation in vitro and in vivo, and ...

journal_title：Macromolecular bioscience

authors： Bochyńska AI,Hannink G,Rongen JJ,Grijpma DW,Buma P

更新日期：2017-11-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is an important protein for wound healing and angiogenesis in tissue engineering, but the lack of a viable delivery system hampers its clinical application. This study aims to maintain the long-term controlled release of bFGF by utilizing a collagen/heparin bi-affinity multilayer ...

journal_title：Macromolecular bioscience

authors： Hao W,Han J,Chu Y,Huang L,Zhuang Y,Sun J,Li X,Zhao Y,Chen Y,Dai J

更新日期：2018-11-01 00:00:00

abstract：:Local, micromechanical environment is known to influence cellular function in heterogeneous hydrogels, and knowledge gained in micromechanics will facilitate the improved design of biomaterials for tissue regeneration. In this study, a system comprising microstructured resilin-like polypeptide (RLP)-poly(ethylene glyc...

journal_title：Macromolecular bioscience

authors： Lau HK,Rattan S,Fu H,Garcia CG,Barber DM,Kiick KL,Crosby AJ

更新日期：2020-05-01 00:00:00

abstract：:Amino acid ester substituted polyphosphazenes are osteoactive benefiting from their phosphorus-containing chemical structure, which highlights interests in bone tissue engineering. To correlate their chemical structures with cell activities, in this study, poly[(ethyl alanato)0.3 (ethyl glycinato)0.7 phosphazene] (PAG...

journal_title：Macromolecular bioscience

authors： Huang Z,Yang L,Hu X,Huang Y,Cai Q,Ao Y,Yang X

更新日期：2019-06-01 00:00:00