The Role of Charge Density and Hydrophobicity on the Biocidal Properties of Self-Protonable Polymeric Materials.

abstract：:A nanoscale biodegradable polymersome with pH-tuning on-off membrane is prepared via the self-assembly of poly(β-amino ester)-based amphiphilic copolymers. The pH-sensitive polymersome-like vesicle structure includes two layers that can encapsulate either hydrophobic or hydrophilic therapeutic drugs at physiological p...

journal_title：Macromolecular bioscience

authors： Jeong IK,Gao GH,Li Y,Kang SW,Lee DS

更新日期：2013-07-01 00:00:00

abstract：:The phase behavior of a water/hydroxypropyl cellulose/maleic acid-styrene copolymer (H2O/HPC/MAc-S) system was investigated in the semi-dilute range by turbidimetry, rheology, and optical microscopy. The two polymers under investigation form interpolymer complexes via hydrogen bonding. In the case of a total polymer c...

journal_title：Macromolecular bioscience

authors： Bumbu GG,Eckelt J,Wolf BA,Vasile C

更新日期：2005-10-20 00:00:00

abstract：:A series of enzymatically recyclable poly(ester-urethane)s consisting of a biodegradable diurethane moiety as a hard segment and an ester moiety as an enzymatically cleavable linkage was chemo-enzymatically prepared by two routes. The poly(ester-urethane) was prepared by a) the ring-opening polymerization of a cyclic ...

journal_title：Macromolecular bioscience

authors： Soeda Y,Toshima K,Matsumura S

更新日期：2005-04-19 00:00:00

abstract：:Redox-responsive micelles are versatile nanoplatforms for on-demand drug delivery, but the in situ evaluation of drug release is challenging. Fluorescence resonance energy transfer (FRET) technique shows potential for addressing this, while the aggregation-caused quenching effect limits the assay sensitivity. The aim ...

journal_title：Macromolecular bioscience

authors： Wang X,Li J,Yan Q,Chen Y,Fan A,Wang Z,Zhao Y

更新日期：2018-03-01 00:00:00

abstract：:Silk fibroin is a useful protein polymer for biomaterials and tissue engineering. In this work, porogen leached scaffolds prepared from aqueous and HFIP silk solutions were reinforced through the addition of silk particles. This led to about 40 times increase in the specific compressive modulus and the yield strength ...

journal_title：Macromolecular bioscience

authors： Rajkhowa R,Gil ES,Kluge J,Numata K,Wang L,Wang X,Kaplan DL

更新日期：2010-06-11 00:00:00

abstract：:Excessive bilirubin in the body of patient with liver dysfunction or metabolic obstruction may cause jaundice with irreversible brain damage, and new type of adsorbent for bilirubin is under frequent investigation. Herein, graphene oxide based core @ polyethersulfone-based shell beads are fabricated by phase inversion...

journal_title：Macromolecular bioscience

authors： He C,Li M,Zhang J,Yan B,Zhao W,Sun S,Zhao C

更新日期：2020-08-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is an important protein for wound healing and angiogenesis in tissue engineering, but the lack of a viable delivery system hampers its clinical application. This study aims to maintain the long-term controlled release of bFGF by utilizing a collagen/heparin bi-affinity multilayer ...

journal_title：Macromolecular bioscience

authors： Hao W,Han J,Chu Y,Huang L,Zhuang Y,Sun J,Li X,Zhao Y,Chen Y,Dai J

更新日期：2018-11-01 00:00:00

abstract：:Stereolithography-assisted fabrication of hydrogels of carboxybetaine methacrylamide (CBMAA) and a α,ω-methacrylate poly(d,l-lactide-block-ethylene glycol-block- d,l-lactide) (MA-PDLLA-PEG-PDLLA-MA) telechelic triblock macromer is presented. This technique allows printing complex structures with gyroid interconnected ...

journal_title：Macromolecular bioscience

authors： Kostina NY,Blanquer S,Pop-Georgievski O,Rahimi K,Dittrich B,Höcherl A,Michálek J,Grijpma DW,Rodriguez-Emmenegger C

更新日期：2019-04-01 00:00:00

abstract：:Cardiovascular diseases, including myocardial infarction, are the cause of significant morbidity and mortality globally. Tissue engineering is a key emerging treatment method for supporting and repairing the cardiac scar tissue caused by myocardial infarction. Creating cell supportive scaffolds that can be directly im...

journal_title：Macromolecular bioscience

authors： Sherrell PC,Cieślar-Pobuda A,Ejneby MS,Sammalisto L,Gelmi A,de Muinck E,Brask J,Łos MJ,Rafat M

更新日期：2017-07-01 00:00:00

abstract：:Pulmonary air leaks are medical complications of thoracic surgery for which fibrin sealant is the main treatment. In this study, innovative sealants based on hydrophobically modified Alaska pollock-derived gelatin (hm-ApGltn) and a poly(ethylene)glycol-based 4-armed cross-linker (4S-PEG) have been developed and their ...

journal_title：Macromolecular bioscience

authors： Mizuta R,Taguchi T

更新日期：2017-04-01 00:00:00

abstract：:The polyethylenimine (PEI) derivatives (PTn) are prepared by treating PEI25k with Tris(hydroxymethyl) acrylamidomethane via the Michael addition. These PTns can effectively condense nucleic acids into nanosized particles with positive surface charges. The PTns show lower cytotoxicity and better serum-resistant capacit...

journal_title：Macromolecular bioscience

authors： Dong X,Lin L,Chen J,Guo Z,Tian H,Li Y,Wei Y,Chen X

更新日期：2013-04-01 00:00:00

abstract：:Given the major structural role phosphodiesters play in the organism it is surprising they have not been more widely adopted as a building block in sophisticated biomimetic hydrogels and other biomaterials. The potential benefits are substantial: phosphoester-based materials show excellent compatibility with blood, ce...

journal_title：Macromolecular bioscience

authors： Dera R,Diliën H,Billen B,Gagliardi M,Rahimi N,Van Den Akker NMS,Molin DGM,Grandfils C,Adriaensens P,Guedens W,Cleij TJ

更新日期：2019-07-01 00:00:00

abstract：:Manipulated roughness has been etched on nanofibers to modulate adsorption of serum proteins for serum-free cells cultivation. Mixtures of Polycaprolactone and Pluronic with various blending ratios are electrospun to nanofibers and Pluronic is subsequently leached out by methanol. Electron microscopy reveals that surf...

journal_title：Macromolecular bioscience

authors： Mao W,Yoo HS

更新日期：2017-08-01 00:00:00

abstract：:A CMB monomer was polymerized on a glass plate with a surface-confined ATRP initiator containing a 2-bromoisobutyryl group. The glass plate modified with a PCMB brush was highly hydrophilic and showed a strong resistance against non-specific adsorption of proteins and cell adhesion. Upon ion beam irradiation, furtherm...

journal_title：Macromolecular bioscience

authors： Kitano H,Suzuki H,Kondo T,Sasaki K,Iwanaga S,Nakamura M,Ohno K,Saruwatari Y

更新日期：2011-04-08 00:00:00

abstract：:In the last decade, substantial research in the field of post-plasma grafting surface modification has focussed on the introduction of carboxylic acids on surfaces by grafting acrylic acid (AAc). In the present work, we report on an alternative approach for biomaterial surface functionalisation. Thin poly-ε-caprolacto...

journal_title：Macromolecular bioscience

authors： Desmet T,Billiet T,Berneel E,Cornelissen R,Schaubroeck D,Schacht E,Dubruel P

更新日期：2010-12-08 00:00:00

abstract：:The present study investigates the effect of galactosylated gelatin on encapsulated HepG2 cells. Methacrylamide modified gelatin is evaluated and compared with its galactosylated counterpart with respect to effects on viability, morphological characteristics, proliferation, and the expression of hepatocyte specific ma...

journal_title：Macromolecular bioscience

authors： Gevaert E,Billiet T,Declercq H,Dubruel P,Cornelissen R

更新日期：2014-03-01 00:00:00

abstract：:The repair of large crushed or sectioned segments of peripheral nerves remains a challenge in regenerative medicine due to the complexity of the biological environment and the lack of proper biomaterials and architecture to foster reconstruction. Traditionally such reconstruction is only achieved by using fresh human ...

journal_title：Macromolecular bioscience

authors： Belanger K,Dinis TM,Taourirt S,Vidal G,Kaplan DL,Egles C

更新日期：2016-04-01 00:00:00

abstract：:The present study describes the synthesis of novel polypeptides containing O-phospho-L-threonine [Thr(PO(3)H(2))] and L-aspartic acid. Random copolypeptides copoly[Thr(PO(3)H(2))(X)Asp(Y)] (X:Y = 25:75, 50:50, 75:25), were conventionally prepared by copolymerization of Thr(PO(3)Ph(2)) N-carboxyanhydride (NCA) and Asp(...

journal_title：Macromolecular bioscience

authors： Hayashi S,Ohkawa K,Yamamoto H

更新日期：2006-03-14 00:00:00

abstract：:Surface structural characterisation of three different starch-based blends (with poly[ethylene-co-(vinyl alcohol)], cellulose acetate and polycaprolactone) was carried out. The results show that there is a difference between the bulk and the surface composition of all studied blends. Two different hypotheses were inve...

journal_title：Macromolecular bioscience

authors： Pashkuleva I,Azevedo HS,Reis RL

更新日期：2008-02-11 00:00:00

abstract：:The major route to convert lactic acid to high-molecular-weight polymers is ring-opening polymerization of lactide. We have investigated alternative synthesis routes based on oligomerization and chain linking to produce high-molecular-weight thermoplastic degradable polymers cost-effectively. Chain linking also offers...

journal_title：Macromolecular bioscience

authors： Seppälä JV,Helminen AO,Korhonen H

更新日期：2004-03-15 00:00:00

abstract：:Bone loss through traumatic injury is a significant clinical issue. Researchers have created many scaffold types to mimic an extracellular matrix to provide structural support for the formation of new bone, however functional regeneration of larger scaffolds has not been fully achieved. Newer scaffolds aim to deliver ...

journal_title：Macromolecular bioscience

authors： Lanier OL,Ficarrotta JM,Adjei I,Wable D,Lewis C,Nacea C,Sharma B,Dobson J,McFetridge P

更新日期：2021-01-01 00:00:00

abstract：:In many industrial applications, inadequate cell attachment can be a limitation, especially when serum-free media are used. Nitrogen-rich plasma-polymerised ethylene (PPE:N) exhibits high concentrations of polar groups that can help to promote the attachment of weakly adherent cell types. Tissue plasminogen activator-...

journal_title：Macromolecular bioscience

authors： Gigout A,Levasseur S,Girard-Lauriault PL,Buschmann MD,Wertheimer MR,Jolicoeur M

更新日期：2009-10-08 00:00:00

abstract：:In drug delivery to the human brain, blood vessels are a significant hurdle because they restrict the entry of most solutes to protect brain. To overcome this hurdle, an in vitro 3D model for brain endothelial barrier is developed using a microfluidic device with hydrogel providing a 3D extracellular matrix scaffold. ...

journal_title：Macromolecular bioscience

authors： Chung B,Kim J,Nam J,Kim H,Jeong Y,Liu HW,Cho Y,Kim YH,Oh HJ,Chung S

更新日期：2020-06-01 00:00:00

abstract：:Integration of electrogenic microorganisms remains a challenge in biofuel cell technology. Here, synthetic biocomposites ("artificial biofilms") are proposed. Bacteria (Shewanella oneidensis) are embedded in a hydrogel matrix (poly(vinyl alcohol)) via wet- and electrospinning, creating fibers and nonwoven gauzes. The ...

journal_title：Macromolecular bioscience

authors： Kaiser P,Reich S,Leykam D,Willert-Porada M,Greiner A,Freitag R

更新日期：2017-07-01 00:00:00

abstract：:S-Layer proteins are an example of bionanostructures that can be exploited in nanofabrication. In addition to their ordered structure, the ability to self-assembly is a key feature that makes them a promising technological tool. Here, in vitro self-assembly kinetics of SpbA was investigated, and found that it occurs a...

journal_title：Macromolecular bioscience

authors： Teixeira LM,Strickland A,Mark SS,Bergkvist M,Sierra-Sastre Y,Batt CA

更新日期：2010-02-11 00:00:00

abstract：:Solution-grown chain-folded lamellar single crystals of poly(tetramethylene adipate) (PTMA) were prepared from a dilute solution of 2-methyl-1-propanol by isothermal crystallization. PTMA crystals were hexagonal-shaped and polyethylene decoration of the crystals resulted in a "six cross-sector" surface morphology and ...

journal_title：Macromolecular bioscience

authors： Iwata T,Kobayashi S,Tabata K,Yonezawa N,Doi Y

更新日期：2004-03-15 00:00:00

abstract：:The material surface must be considered in the design of scaffolds for bone tissue engineering so that it supports bone cells adhesion, proliferation and differentiation. A biomimetic approach has been developed as a 3D surface modification technique to grow partially carbonated hydroxyapatite (the bonelike mineral) i...

journal_title：Macromolecular bioscience

authors： Zhang R,Ma PX

更新日期：2004-02-20 00:00:00

abstract：:Cell adhesion to a scaffold is a prerequisite for tissue engineering. Many studies have been focused on enhancing cell adhesion to synthetic materials that are used for scaffold fabrication. In this study, we applied an avidin-biotin binding system to enhance chondrocyte adhesion to biodegradable polymers. Biotin mole...

journal_title：Macromolecular bioscience

authors： Tsai WB,Wang MC

更新日期：2005-03-15 00:00:00

abstract：:Extraction processes of natural fibers can be performed by different procedures that include mechanical, chemical and biological methods. Each method presents different advantages or drawbacks according to the amount of fiber produced or the quality and properties of fiber bundles obtained. In this study, biological n...

journal_title：Macromolecular bioscience

authors： Gañán P,Zuluaga R,Velez JM,Mondragon I

更新日期：2004-10-20 00:00:00

abstract：:Biodegradable hydrogels were synthesized by the click reaction of 4-arm azido-terminated PEG differing in molecular weight (2,100 and 8,800) and two alkyne-terminated peptides: [alkyne]-GFLGK-[alkyne] and ([alkyne]-GFLG)(2)K. The physical properties of in situ formed hydrogels were examined. The hydrogels were highly ...

journal_title：Macromolecular bioscience

authors： Yang J,Jacobsen MT,Pan H,Kopecek J

更新日期：2010-04-08 00:00:00