Pluronic-Induced Surface Etching of Biodegradable Nanofibers for Enhanced Adsorption of Serum Protein.

abstract：:Basic fibroblast growth factor (bFGF) is an important protein for wound healing and angiogenesis in tissue engineering, but the lack of a viable delivery system hampers its clinical application. This study aims to maintain the long-term controlled release of bFGF by utilizing a collagen/heparin bi-affinity multilayer ...

journal_title：Macromolecular bioscience

authors： Hao W,Han J,Chu Y,Huang L,Zhuang Y,Sun J,Li X,Zhao Y,Chen Y,Dai J

更新日期：2018-11-01 00:00:00

abstract：:To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with inc...

journal_title：Macromolecular bioscience

authors： Hou S,McCauley LK,Ma PX

更新日期：2007-05-10 00:00:00

abstract：:Currently, there is no gadolinium-based contrast agent available for conventional magnetic resonance imaging (MRI) detection of amyloidal beta (Aβ) plaques in Alzheimer's disease (AD). Its timely finding would be vital for patient survival and quality of life. Curcumin (CUR), a common Indian spice effectively binds to...

journal_title：Macromolecular bioscience

authors： Patil R,Gangalum PR,Wagner S,Portilla-Arias J,Ding H,Rekechenetskiy A,Konda B,Inoue S,Black KL,Ljubimova JY,Holler E

更新日期：2015-09-01 00:00:00

abstract：:A microfluidic technique is described to encapsulate living cells in alginate hydrogel microparticles generated from monodisperse double-emulsion templates. A microcapillary device is used to fabricate double emulsion templates composed of an alginate drop surrounded by a mineral oil shell. Hydrogel formation begins w...

journal_title：Macromolecular bioscience

authors： Martinez CJ,Kim JW,Ye C,Ortiz I,Rowat AC,Marquez M,Weitz D

更新日期：2012-07-01 00:00:00

abstract：:This work focuses on the development of ultrasound contrast vesicles for ultrasound-mediated enhanced transfection of nucleic acids in the cancer cells and projects its application as a tool for diagnostic imaging. The ultrasound contrast vesicles are stable, anionic, nanoscaled vesicles with ultrasound contrast equiv...

journal_title：Macromolecular bioscience

authors： Shah H,Tariq I,Engelhardt K,Bakowsky U,Pinnapireddy SR

更新日期：2020-12-01 00:00:00

abstract：:A nanoscale biodegradable polymersome with pH-tuning on-off membrane is prepared via the self-assembly of poly(β-amino ester)-based amphiphilic copolymers. The pH-sensitive polymersome-like vesicle structure includes two layers that can encapsulate either hydrophobic or hydrophilic therapeutic drugs at physiological p...

journal_title：Macromolecular bioscience

authors： Jeong IK,Gao GH,Li Y,Kang SW,Lee DS

更新日期：2013-07-01 00:00:00

abstract：:The remedy for infected chronic wounds such as diabetic foot ulcers is more complicated particularly in the case of patients with an inefficient immune system. Also, fighting against microbial infections in the wound site by available antibiotics may not be effective because of emerging antibiotic resistance propertie...

journal_title：Macromolecular bioscience

authors： Alavi M,Nokhodchi A

更新日期：2020-04-01 00:00:00

abstract：:Accurate prediction and validation of the assembly of bioinspired peptide sequences into fibers with defined mechanical characteristics would aid significantly in designing and creating materials with desired properties. This process may also be utilized to provide insight into how the molecular architecture of many n...

journal_title：Macromolecular bioscience

authors： Jacobsen MM,Tokareva OS,Ebrahimi D,Huang W,Ling S,Dinjaski N,Li D,Simon M,Staii C,Buehler MJ,Kaplan DL,Wong JY

更新日期：2017-09-01 00:00:00

abstract：:Novel block copolymers using the monomers 5-(2-methoxyethyoxymethyl)-5-methyl-[1,3]-dioxa-2-one (TMCM-MOE1OM) as a hydrophilic segment and lactides as a hydrophobic segment were designed in order to prepare controllable degradation polymers by dynamic polymer rearrangement based on the hydrophilicity. When the copolym...

journal_title：Macromolecular bioscience

authors： Ajiro H,Takahashi Y,Akashi M,Fujiwara T

更新日期：2012-10-01 00:00:00

abstract：:The effect of doping graphene oxide (GO) and reduced graphene oxide (rGO) into poly(ε-caprolactone) (PCL) membranes prepared by solvent induced phase separation is evaluated in terms of nanomaterial distribution and compatibility with neural stem cell growth and functional differentiation. Raman spectra analyses demon...

journal_title：Macromolecular bioscience

authors： Sánchez-González S,Diban N,Bianchi F,Ye H,Urtiaga A

更新日期：2018-11-01 00:00:00

abstract：:Comb-shaped glycopolymer/peptide bioconjugates are constructed by grafting reduced glutathione (GSH) onto acrylate-functional block glycocopolymers via thiol-ene click chemistry. In aqueous solution, the glycopolymer/GSH bioconjugate self-assembles to sugar-installed spherical micelles. The size of micelles decreases ...

journal_title：Macromolecular bioscience

authors： Wang X,Liu L,Luo Y,Shi H,Li J,Zhao H

更新日期：2012-11-01 00:00:00

abstract：:Injectable hydrogels are extensively used in drug delivery and tissue engineering to administer drugs, genes, growth factors and live cells. We report a method to produce tough, in-situ thermogelling, non-toxic, injectable hydrogels made of chitosan and hyaluronic acid co-crosslinked with β-glycerophophate and genipin...

journal_title：Macromolecular bioscience

authors： Jalani G,Rosenzweig DH,Makhoul G,Abdalla S,Cecere R,Vetrone F,Haglund L,Cerruti M

更新日期：2015-04-01 00:00:00

abstract：:The preparation of histidine enriched dendritic peptide amphiphiles and their self-assembly into multicomponent pH-switchable supramolecular polymers is reported. Alternating histidine and phenylalanine peptide synthons allow the assembly/disassembly to be adjusted in a physiologically relevant range of pH 5.3-6.0. Co...

journal_title：Macromolecular bioscience

authors： Ahlers P,Frisch H,Holm R,Spitzer D,Barz M,Besenius P

更新日期：2017-10-01 00:00:00

abstract：:Surface structural characterisation of three different starch-based blends (with poly[ethylene-co-(vinyl alcohol)], cellulose acetate and polycaprolactone) was carried out. The results show that there is a difference between the bulk and the surface composition of all studied blends. Two different hypotheses were inve...

journal_title：Macromolecular bioscience

authors： Pashkuleva I,Azevedo HS,Reis RL

更新日期：2008-02-11 00:00:00

abstract：:Mucoadhesive NP drug carriers have attracted substantial interest as a potential treatment for anterior eye diseases. NPs composed of PLA-Dex surface functionalized with a mucoadhesive ligand, PBA, were developed as drug carriers with particle sizes ranging from 25 to 28 nm. Using CycA as a model drug, we showed that ...

journal_title：Macromolecular bioscience

authors： Liu S,Jones L,Gu FX

更新日期：2012-12-01 00:00:00

abstract：:Since the early 1980s, research on the modification of bone implant surfaces by applying coatings has mainly focused on the application of inorganic calcium phosphate (CaP) coatings using physical deposition techniques. Organic components of the extracellular bone matrix, on the other hand, play an essential role in t...

journal_title：Macromolecular bioscience

authors： Nijhuis AW,Leeuwenburgh SC,Jansen JA

更新日期：2010-11-10 00:00:00

abstract：:We report the self-assembly of a series of amphiphilic diblock copolymers comprising a biocompatible, hydrophilic block, poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and a pH-sensitive block, poly(2-(diisopropylamino)ethyl methacrylate) (PDPA), into a dispersion of colloidally stable, nanometer-sized polymers...

journal_title：Macromolecular bioscience

authors： Lomas H,Du J,Canton I,Madsen J,Warren N,Armes SP,Lewis AL,Battaglia G

更新日期：2010-05-14 00:00:00

abstract：:Traditionally, conductive materials for electrodes are based on high modulus metals or alloys. Development of bioelectrodes that mimic the mechanical properties of the soft, low modulus tissues in which they are implanted is a rapidly expanding field of research. Many polymers exist that more closely match tissue mech...

journal_title：Macromolecular bioscience

authors： Patton AJ,Poole-Warren LA,Green RA

更新日期：2016-08-01 00:00:00

abstract：:Extraction processes of natural fibers can be performed by different procedures that include mechanical, chemical and biological methods. Each method presents different advantages or drawbacks according to the amount of fiber produced or the quality and properties of fiber bundles obtained. In this study, biological n...

journal_title：Macromolecular bioscience

authors： Gañán P,Zuluaga R,Velez JM,Mondragon I

更新日期：2004-10-20 00:00:00

abstract：:Peptide dendrimers assembled by solid-phase peptide synthesis using a branching diamino acid at every 2(nd) or 3(rd) position provide readily accessible synthetic model systems for proteins and enzymes. They adopt a globular shape by topology rather than by folding. Peptide dendrimers of 2(nd) and 3(rd) generation fun...

journal_title：Macromolecular bioscience

authors： Delort E,Szöcs E,Widmer R,Siegenthaler H,Reymond JL

更新日期：2007-08-07 00:00:00

abstract：:Tissue adhesives are an attractive class of biomaterials, which can serve as a treatment for meniscus tears. In this study, physicochemical and adhesive properties of novel biodegradable three-armed- and hyperbranched block copolymeric adhesives are evaluated. Additionally, their degradation in vitro and in vivo, and ...

journal_title：Macromolecular bioscience

authors： Bochyńska AI,Hannink G,Rongen JJ,Grijpma DW,Buma P

更新日期：2017-11-01 00:00:00

abstract：:Treatment of retinal diseases currently demands frequent intravitreal injections due to rapid clearance of the therapeutics. The use of high molecular weight polymers can extend the residence time in the vitreous and prolong the injection intervals. This study reports a water soluble graft copolymer as a potential veh...

journal_title：Macromolecular bioscience

authors： Borke T,Najberg M,Ilina P,Bhattacharya M,Urtti A,Tenhu H,Hietala S

更新日期：2018-01-01 00:00:00

abstract：:In-depth understanding of the biophysicochemical interactions at the nano-bio interface is important for basic cell biology and applications in nanomedicine and nanobiosensors. Here, the extracellular surface potential and topography changes of live cell membranes interacting with polymeric nanomaterials using a scann...

journal_title：Macromolecular bioscience

authors： Chen F,Manandhar P,Ahmed MS,Chang S,Panday N,Zhang H,Moon JH,He J

更新日期：2019-02-01 00:00:00

abstract：:Fluorescent dye labeled unfunctionalized and functionalized poly(n-butylcyanoacrylate) nanoparticles were prepared using a miniemulsion technique. Amino acid and methoxyPEG functionalization could be introduced by using aqueous solutions as an initiator for the anionic polymerization in the heterophase. All the partic...

journal_title：Macromolecular bioscience

authors： Weiss CK,Lorenz MR,Landfester K,Mailänder V

更新日期：2007-07-09 00:00:00

abstract：:Poly[(R)-3-hydroxybutyrate] (P(3HB)) and its copolymers are accumulated by a wide variety of microorganisms as intracellular carbon and energy material, and are extensively studied as biodegradable and biocompatible thermoplastics. However, these microbial polyesters have not been recognized as practical because of th...

journal_title：Macromolecular bioscience

authors： Iwata T

更新日期：2005-08-12 00:00:00

abstract：:"Three-layered micelles" (3LM) composed of two triblock copolymers, poly(L-lactide)-b-polyethyleneimine-b-poly(L-lactide) (PLLA-PEI-PLLA) and poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) (PLLA-PEG-PLLA) are designed to combine electrostatic interaction and solvent-induced condensation of DNA. The low mole...

journal_title：Macromolecular bioscience

authors： Abebe DG,Kandil R,Kraus T,Elsayed M,Merkel OM,Fujiwara T

更新日期：2015-05-01 00:00:00

abstract：:[Image: see text] Oligosaccharides at cell surfaces are known to play a critical role in many biological processes such as biorecognition, interactions between cells and with artificial surfaces, immune response, infection and inflammation. In order to facilitate studies of the role of sugars, an increasing number of ...

journal_title：Macromolecular bioscience

authors： Coullerez G,Seeberger PH,Textor M

更新日期：2006-08-07 00:00:00

abstract：:In this paper, a novel composite hydrogel was prepared by the use of dialdehyde konjac glucomannan (DAK) as macromolecular cross-linking agent for chitosan (CS). This biocompatible material cross-links and gels in minutes. The structure and morphology were characterized by various analyses. The results indicate that t...

journal_title：Macromolecular bioscience

authors： Yu H,Lu J,Xiao C

更新日期：2007-09-11 00:00:00

abstract：:Primary human megakaryocytes, the precursor cells of platelets, are difficult to collect and cultivate. Polymers that enrich these cells without affecting their regulation or function are of interest for basic research as well as for cord blood transplantation purposes since co-transplantation of enriched megakaryocyt...

journal_title：Macromolecular bioscience

authors： Hansen A,Corless S,Cleland A,Petrik J,Gilbert N,Bradley M

更新日期：2013-04-01 00:00:00

abstract：:Bioinks play a key role in determining the capability of the biofabricatoin processes and the resolution of the printed constructs. Excellent biocompatibility, tunable physical properties, and ease of chemical or biological modifications of gelatin methacryloyl (GelMA) have made it an attractive choice as bioinks for ...

journal_title：Macromolecular bioscience

authors： Kumar H,Sakthivel K,Mohamed MGA,Boras E,Shin SR,Kim K

更新日期：2021-01-01 00:00:00