Development and Characterization of Ultrasound Activated Lipopolyplexes for Enhanced Transfection by Low Frequency Ultrasound in In Vitro Tumor Model.

abstract：:It is of paramount importance to study the cellular uptake processes of particles with defined surface property, especially the uptake pathways and intracellular transportation. In this study, aptamer AS1411 molecules, which are known to specifically bind the over-expressed nucleolin on cancer cell membrane, were conj...

journal_title：Macromolecular bioscience

authors： Yu D,Zhang Y,Mao Z,Gao C

更新日期：2013-10-01 00:00:00

abstract：:Recombinantly produced spider silk proteins have high potential for bioengineering and various biomedical applications because of their biocompatibility, biodegradability, and low immunogenicity. Here, the recently described small spider silk protein eMaSp1s is assembled into hydrogels, which can be 3D printed into sc...

journal_title：Macromolecular bioscience

authors： Thamm C,DeSimone E,Scheibel T

更新日期：2017-11-01 00:00:00

abstract：:Diblock and multiblock copolymers composed of a poly(D,L-lactide) (PLA) or poly(trimethylene carbonate) (PTMC) core with a hydrophilic chain of poly(ethylene glycol) (PEG) were prepared. These copolymers, in which the core is connected to PEG through a polyfunctional molecule such as citric, mucic, or tartaric acid, m...

journal_title：Macromolecular bioscience

authors： Ben-Shabat S,Kumar N,Domb AJ

更新日期：2006-12-08 00:00:00

abstract：:Several high-resolution imaging techniques such as FESEM, TEM and AFM are compared with respect to their application on alginate hydrogels, a widely used polysaccharide biomaterial. A new AFM method applicable to RGD peptides covalently conjugated to alginate hydrogels is described. High-resolution images of RGD adhes...

journal_title：Macromolecular bioscience

authors： Hsiong SX,Cooke PH,Kong HJ,Fishman ML,Ericsson M,Mooney DJ

更新日期：2008-06-11 00:00:00

abstract：:In this paper, a novel composite hydrogel was prepared by the use of dialdehyde konjac glucomannan (DAK) as macromolecular cross-linking agent for chitosan (CS). This biocompatible material cross-links and gels in minutes. The structure and morphology were characterized by various analyses. The results indicate that t...

journal_title：Macromolecular bioscience

authors： Yu H,Lu J,Xiao C

更新日期：2007-09-11 00:00:00

abstract：:Plasmid DNA (pDNA) is encapsulated into biocompatible microgels by an inverse microemulsion polymerization method. Plasmid DNA and doxorubicin are successfully released from pDNA microgels and their release profiles are characterized by appropriate release models. The co-delivery of genes and drugs from the microgels ...

journal_title：Macromolecular bioscience

authors： Costa D,Valente AJ,Miguel MG,Queiroz J

更新日期：2012-09-01 00:00:00

abstract：:Melanin is an effective absorber of light and can extend to near infrared (NIR) regions. In this study, a natural melanin is presented as a photothermal therapeutic agent (PTA) because it provides a good photothermal conversion efficiency, shows biodegradability, and does not induce long-term toxicity during retention...

journal_title：Macromolecular bioscience

authors： Kim M,Kim HS,Kim MA,Ryu H,Jeong HJ,Lee CM

更新日期：2017-05-01 00:00:00

abstract：:3D hydrogels better replicate in vivo conditions, and yield different results from 2D substrates. However, imaging interactions between cells and the hydrogel microenvironment is challenging because of light diffraction and poor focal depth. Here, cryosectioning and vibrating microtomy methods and fixation protocols a...

journal_title：Macromolecular bioscience

authors： Short AR,Czeisler C,Stocker B,Cole S,Otero JJ,Winter JO

更新日期：2017-06-01 00:00:00

abstract：:Peptide dendrimers assembled by solid-phase peptide synthesis using a branching diamino acid at every 2(nd) or 3(rd) position provide readily accessible synthetic model systems for proteins and enzymes. They adopt a globular shape by topology rather than by folding. Peptide dendrimers of 2(nd) and 3(rd) generation fun...

journal_title：Macromolecular bioscience

authors： Delort E,Szöcs E,Widmer R,Siegenthaler H,Reymond JL

更新日期：2007-08-07 00:00:00

abstract：:Stereolithography-assisted fabrication of hydrogels of carboxybetaine methacrylamide (CBMAA) and a α,ω-methacrylate poly(d,l-lactide-block-ethylene glycol-block- d,l-lactide) (MA-PDLLA-PEG-PDLLA-MA) telechelic triblock macromer is presented. This technique allows printing complex structures with gyroid interconnected ...

journal_title：Macromolecular bioscience

authors： Kostina NY,Blanquer S,Pop-Georgievski O,Rahimi K,Dittrich B,Höcherl A,Michálek J,Grijpma DW,Rodriguez-Emmenegger C

更新日期：2019-04-01 00:00:00

abstract：:Because of the high mortality of coronary atherosclerotic heart diseases, it is necessary to develop novel early detection methods for vulnerable atherosclerotic plaques. Phenotype transformation of vascular smooth muscle cells (VSMCs) plays a vital role in progressed atherosclerotic plaques. Osteopontin (OPN) is one ...

journal_title：Macromolecular bioscience

authors： Li S,Gou T,Wang Q,Chen M,Chen Z,Xu M,Wang Y,Han D,Cao R,Liu J,Liang P,Dai Z,Cao F

更新日期：2020-02-01 00:00:00

abstract：:We present a two-fold study designed to elucidate the adhesion mechanism of human U937 monocytes on novel N-rich thin films deposited by plasma- and VUV photo-polymerisation, so-called "PVP:N" materials. It is shown that there exist sharply-defined ("critical") surface-chemical conditions that are necessary to induce ...

journal_title：Macromolecular bioscience

authors： Girard-Lauriault PL,Truica-Marasescu F,Petit A,Wang HT,Desjardins P,Antoniou J,Mwale F,Wertheimer MR

更新日期：2009-09-09 00:00:00

abstract：:A poly(o-methoxyaniline) (POMA)/DNA [weight fraction of DNA (W(DNA)) = 0.45] hybrid was prepared by mixing their solutions in sterilized double distilled water. The solution turned green upon aging for a longer time, and the doping of POMA by DNA was complete after about 15 d of aging. The doping was confirmed from th...

journal_title：Macromolecular bioscience

authors： Dawn A,Nandi AK

更新日期：2005-05-23 00:00:00

abstract：:The use of PLA and PLA-g-AA/starch as materials for the controlled release of encapsulated PSB was evaluated. The results showed that the bacterium degraded both the PLA and the PLA-g-AA/starch composite films, resulting in cell release. Severe disruption of the film structure occurred after incubation for 60-90 d. Th...

journal_title：Macromolecular bioscience

authors： Wu CS

更新日期：2008-06-11 00:00:00

abstract：:The polyethylenimine (PEI) derivatives (PTn) are prepared by treating PEI25k with Tris(hydroxymethyl) acrylamidomethane via the Michael addition. These PTns can effectively condense nucleic acids into nanosized particles with positive surface charges. The PTns show lower cytotoxicity and better serum-resistant capacit...

journal_title：Macromolecular bioscience

authors： Dong X,Lin L,Chen J,Guo Z,Tian H,Li Y,Wei Y,Chen X

更新日期：2013-04-01 00:00:00

abstract：:Chitin is the second most abundant natural polysaccharide with biocompatibility and bioactivity. Aqueous KOH/urea solution is reported for rapid dissolution of chitin, therefore providing a greener and more efficient avenue to fabricate chitin-based functional materials. Chitosan is the most important derivative of ch...

journal_title：Macromolecular bioscience

authors： Xu H,Zhang L,Zhang H,Luo J,Gao X

更新日期：2021-01-18 00:00:00

abstract：:A facile and easily reproducible technique for assembling biohybrid nanoparticles is a core feature that is highly desired for biomedical applications, considering the nature and limited lifespan of the biopolymers used. Here we show a simple and effective method to enfold single-walled carbon nanotubes (SWNTs) using ...

journal_title：Macromolecular bioscience

authors： Kotagiri N,Kim JW

更新日期：2010-03-10 00:00:00

abstract：:Poly[(R)-3-hydroxybutyrate] (P(3HB)) and its copolymers are accumulated by a wide variety of microorganisms as intracellular carbon and energy material, and are extensively studied as biodegradable and biocompatible thermoplastics. However, these microbial polyesters have not been recognized as practical because of th...

journal_title：Macromolecular bioscience

authors： Iwata T

更新日期：2005-08-12 00:00:00

abstract：:Multicomponent systems for self-assembled molecular gels provide huge opportunities to generate collective or new functions that are not inherent in individual single-component gels. However, gelation tends to require careful and complicated procedures, because, among a myriad of kinetically trapped structures related...

journal_title：Macromolecular bioscience

authors： Hata Y,Kojima T,Maeda T,Sawada T,Serizawa T

更新日期：2020-09-01 00:00:00

abstract：:Cells in physiological 3D environments differ considerably in morphology and differentiation from those in 2D tissue culture. Naturally derived polymer systems are frequently used to study cells in 3D. These 3D matrices are complex with respect to their chemical composition, mechanical properties, and geometry. Theref...

journal_title：Macromolecular bioscience

authors： Greiner AM,Richter B,Bastmeyer M

更新日期：2012-10-01 00:00:00

abstract：:Primary human megakaryocytes, the precursor cells of platelets, are difficult to collect and cultivate. Polymers that enrich these cells without affecting their regulation or function are of interest for basic research as well as for cord blood transplantation purposes since co-transplantation of enriched megakaryocyt...

journal_title：Macromolecular bioscience

authors： Hansen A,Corless S,Cleland A,Petrik J,Gilbert N,Bradley M

更新日期：2013-04-01 00:00:00

abstract：:N-Acetyl-l-cysteine (NAC)-capped poly(methyl methacrylate)-b-polycaprolactone block copolymer (PMMA-b-PCL-NAC) was prepared using the previously described one-pot photoinduced sequential CuAAC/thiol-ene double click procedure. PMMA-b-PCL-NAC had previously shown good applicability as a matrix for cell adhesion of cell...

journal_title：Macromolecular bioscience

authors： Oyman Eyrilmez G,Doran S,Murtezi E,Demir B,Odaci Demirkol D,Coskunol H,Timur S,Yagci Y

更新日期：2015-09-01 00:00:00

abstract：:High-molecular-weight (co)polymers of trimethylene carbonate and D,L-lactide are efficiently crosslinked using PETA during gamma irradiation. Form-stable networks with gel contents of 86 ± 5 to 96 ± 1 are obtained from non-crystalline (co)polymers. Glass transition temperatures and elastic moduli of the networks can b...

journal_title：Macromolecular bioscience

authors： Bat E,van Kooten TG,Feijen J,Grijpma DW

更新日期：2011-07-07 00:00:00

abstract：:Bioinks play a key role in determining the capability of the biofabricatoin processes and the resolution of the printed constructs. Excellent biocompatibility, tunable physical properties, and ease of chemical or biological modifications of gelatin methacryloyl (GelMA) have made it an attractive choice as bioinks for ...

journal_title：Macromolecular bioscience

authors： Kumar H,Sakthivel K,Mohamed MGA,Boras E,Shin SR,Kim K

更新日期：2021-01-01 00:00:00

abstract：:The effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin α1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels signi...

journal_title：Macromolecular bioscience

authors： Kang SW,Cha BH,Park H,Park KS,Lee KY,Lee SH

更新日期：2011-05-12 00:00:00

abstract：:Hydroxypropyl chitosan-graft-carboxymethyl beta-cyclodextrin (HPCH-g-CM beta-CD) was synthesized by grafting CM beta-CD onto HPCH using water soluble 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) as the condensing agent. Due to the presence of hydrophobic beta-CD rings onto the HPCH backbone, this polymer can be...

journal_title：Macromolecular bioscience

authors： Prabaharan M,Mano JF

更新日期：2005-10-20 00:00:00

abstract：:Fluorescent dye labeled unfunctionalized and functionalized poly(n-butylcyanoacrylate) nanoparticles were prepared using a miniemulsion technique. Amino acid and methoxyPEG functionalization could be introduced by using aqueous solutions as an initiator for the anionic polymerization in the heterophase. All the partic...

journal_title：Macromolecular bioscience

authors： Weiss CK,Lorenz MR,Landfester K,Mailänder V

更新日期：2007-07-09 00:00:00

abstract：:A hybrid system for producing conducting polymers within a doping hydrogel mesh is presented. These conductive hydrogels demonstrate comparable electroactivity to conventional conducting polymers without requiring the need for mobile doping ions which are typically used in literature. These hybrids have superior mecha...

journal_title：Macromolecular bioscience

authors： Green RA,Hassarati RT,Goding JA,Baek S,Lovell NH,Martens PJ,Poole-Warren LA

更新日期：2012-04-01 00:00:00

abstract：:The effect of doping graphene oxide (GO) and reduced graphene oxide (rGO) into poly(ε-caprolactone) (PCL) membranes prepared by solvent induced phase separation is evaluated in terms of nanomaterial distribution and compatibility with neural stem cell growth and functional differentiation. Raman spectra analyses demon...

journal_title：Macromolecular bioscience

authors： Sánchez-González S,Diban N,Bianchi F,Ye H,Urtiaga A

更新日期：2018-11-01 00:00:00

abstract：:Branched polyethylenimine (25 kDa) is thiolated and compared with redox-sensitive crosslinked derivatives. Both polymers thiol contents are assessed; the thiolated polymers have 390-2300 mmol SH groups/mol, whereas the crosslinked polymers have lower thiol contents. Cytotoxicity assays show that both modified polymers...

journal_title：Macromolecular bioscience

authors： Aravindan L,Bicknell KA,Brooks G,Khutoryanskiy VV,Williams AC

更新日期：2013-09-01 00:00:00