Synthesis and chemical recycling of novel poly(ester-urethane)s using an enzyme.

abstract：:3D hydrogels better replicate in vivo conditions, and yield different results from 2D substrates. However, imaging interactions between cells and the hydrogel microenvironment is challenging because of light diffraction and poor focal depth. Here, cryosectioning and vibrating microtomy methods and fixation protocols a...

journal_title：Macromolecular bioscience

authors： Short AR,Czeisler C,Stocker B,Cole S,Otero JJ,Winter JO

更新日期：2017-06-01 00:00:00

abstract：:Vessel morphogenesis is vital to regenerative medicine strategies. Here, collagen polymers, specified by intermolecular cross-link composition, are used to independently vary microstructure (fibril density, interfibril branching) and physical properties (stiffness) to guide 3D vessel network formation by endothelial c...

journal_title：Macromolecular bioscience

authors： Whittington CF,Yoder MC,Voytik-Harbin SL

更新日期：2013-09-01 00:00:00

abstract：:Excessive bilirubin in the body of patient with liver dysfunction or metabolic obstruction may cause jaundice with irreversible brain damage, and new type of adsorbent for bilirubin is under frequent investigation. Herein, graphene oxide based core @ polyethersulfone-based shell beads are fabricated by phase inversion...

journal_title：Macromolecular bioscience

authors： He C,Li M,Zhang J,Yan B,Zhao W,Sun S,Zhao C

更新日期：2020-08-01 00:00:00

abstract：:Pedobacter sp. KP-2 can degrade and metabolize thermally synthesized alpha,beta-poly(D,L-aspartic acid) (tPAA), which contains 70% of unnatural beta-amide units, with high-molecular-weight. In this study, gene cloning and molecular characterization of PAA hydrolase-1 from KP-2 was carried out. Gene analysis reveals th...

journal_title：Macromolecular bioscience

authors： Hiraishi T,Masuda E,Kanayama N,Nagata M,Doi Y,Abe H,Maeda M

更新日期：2009-01-09 00:00:00

abstract：:A simple continuous flow wet-spinning method to achieve mechanical reinforcement of the two oppositely charged biopolymers chitosan and gellan gum is described. The mechanical properties of these biopolymers are influenced by the order of addition. Using a facile method for mechanical reinforcement of gellan gum/chito...

journal_title：Macromolecular bioscience

authors： Granero AJ,Razal JM,Wallace GG,in het Panhuis M

更新日期：2009-04-08 00:00:00

abstract：:Two different composite scaffolds, solid-freeform-fabricated PCL/β-TCP supplemented with and without collagen nanofibers are fabricated. These scaffolds are evaluated whether a combination of collagen nanofibers with PCL/β-TCP can promote osteogenesis in a mastoid obliteration. To assess the effects of the cellular ac...

journal_title：Macromolecular bioscience

authors： Jang CH,Cho YB,Yeo MG,Kim GH

更新日期：2013-05-01 00:00:00

abstract：:Multifunctional polymers with defined structure and biocompatibility are critical to the development of drug delivery systems and bioconjugates. In this article, the synthesis, in vitro blood compatibility, cell viability, in vivo circulation, biodistribution, and clearance of hybrid copolymers based on linear and bra...

journal_title：Macromolecular bioscience

authors： Imran ul-haq M,Lai BF,Kizhakkedathu JN

更新日期：2014-10-01 00:00:00

abstract：:A novel cell-supporting scaffold, Tetronic-oligolactide-heparin (TLH) hydrogel, was prepared by coupling heparin to polymerized Tetronic-oligolactide for use in improving tissue regeneration. Aqueous TLH solutions showed thermosensitive behavior, demonstrating potential for use as injectable hydrogels. The content and...

journal_title：Macromolecular bioscience

authors： Go DH,Joung YK,Lee SY,Lee MC,Park KD

更新日期：2008-12-08 00:00:00

abstract：:Artificial ECMs that not only closely mimic the hybrid nature of the natural ECM but also provide tunable material properties and enhanced biological functions are attractive candidates for tissue engineering applications. This review summarizes recent advances in developing multicomponent hybrid hydrogels by integrat...

journal_title：Macromolecular bioscience

authors： Jia X,Kiick KL

更新日期：2009-02-11 00:00:00

abstract：:Chitosan is non-toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofibrous materials is ...

journal_title：Macromolecular bioscience

authors： Ignatova M,Manolova N,Rashkov I

更新日期：2013-07-01 00:00:00

abstract：:A hybrid system for producing conducting polymers within a doping hydrogel mesh is presented. These conductive hydrogels demonstrate comparable electroactivity to conventional conducting polymers without requiring the need for mobile doping ions which are typically used in literature. These hybrids have superior mecha...

journal_title：Macromolecular bioscience

authors： Green RA,Hassarati RT,Goding JA,Baek S,Lovell NH,Martens PJ,Poole-Warren LA

更新日期：2012-04-01 00:00:00

abstract：:In this study, GCC protein was used for the first time to construct a biodegradable conduit for peripheral nerve repair. The GCC was highly stable with a sufficiently high level of mechanical properties and it was non-toxic and non-apoptotic which could maintain the survival and outgrowth of Schwann cells. Noninvasive...

journal_title：Macromolecular bioscience

authors： Wang W,Lin JH,Tsai CC,Chuang HC,Ho CY,Yao CH,Chen YS

更新日期：2011-07-07 00:00:00

abstract：:This study investigates the structural features of porcine gastric mucin (PGM) in aqueous dispersions and its interactions with water-soluble polymers (poly(acrylic acid) (PAA), poly(methacrylic acid) (PMAA), poly(ethylene oxide), and poly(ethylene glycol)) using isothermal titration calorimetry, turbidimetric titrati...

journal_title：Macromolecular bioscience

authors： Albarkah YA,Green RJ,Khutoryanskiy VV

更新日期：2015-11-01 00:00:00

abstract：:The antimicrobial activity of poly(alkyloxazoline) telechelics with one quaternary N,N-dimethyldodecylammonium (DDA) end group was found to be greatly controlled by the non-bioactive distal end group, the so-called satellite group. In systematic investigations, the nature of the latter groups was varied to explore the...

journal_title：Macromolecular bioscience

authors： Waschinski CJ,Herdes V,Schueler F,Tiller JC

更新日期：2005-02-23 00:00:00

abstract：:In-depth understanding of the biophysicochemical interactions at the nano-bio interface is important for basic cell biology and applications in nanomedicine and nanobiosensors. Here, the extracellular surface potential and topography changes of live cell membranes interacting with polymeric nanomaterials using a scann...

journal_title：Macromolecular bioscience

authors： Chen F,Manandhar P,Ahmed MS,Chang S,Panday N,Zhang H,Moon JH,He J

更新日期：2019-02-01 00:00:00

abstract：:Nanoparticles (NP) represent a promising tool for biomedical applications. Here, sulfonate- and phosphonate-functionalized polystyrene NP are analyzed for their interaction with human monocyte-derived dendritic cells (DC). Immature dendritic cells (iDC) display a higher time- and dose-dependent uptake of functionalize...

journal_title：Macromolecular bioscience

authors： Frick SU,Bacher N,Baier G,Mailänder V,Landfester K,Steinbrink K

更新日期：2012-12-01 00:00:00

abstract：:Because of the high mortality of coronary atherosclerotic heart diseases, it is necessary to develop novel early detection methods for vulnerable atherosclerotic plaques. Phenotype transformation of vascular smooth muscle cells (VSMCs) plays a vital role in progressed atherosclerotic plaques. Osteopontin (OPN) is one ...

journal_title：Macromolecular bioscience

authors： Li S,Gou T,Wang Q,Chen M,Chen Z,Xu M,Wang Y,Han D,Cao R,Liu J,Liang P,Dai Z,Cao F

更新日期：2020-02-01 00:00:00

abstract：:The use of PLA and PLA-g-AA/starch as materials for the controlled release of encapsulated PSB was evaluated. The results showed that the bacterium degraded both the PLA and the PLA-g-AA/starch composite films, resulting in cell release. Severe disruption of the film structure occurred after incubation for 60-90 d. Th...

journal_title：Macromolecular bioscience

authors： Wu CS

更新日期：2008-06-11 00:00:00

abstract：:The preparation of histidine enriched dendritic peptide amphiphiles and their self-assembly into multicomponent pH-switchable supramolecular polymers is reported. Alternating histidine and phenylalanine peptide synthons allow the assembly/disassembly to be adjusted in a physiologically relevant range of pH 5.3-6.0. Co...

journal_title：Macromolecular bioscience

authors： Ahlers P,Frisch H,Holm R,Spitzer D,Barz M,Besenius P

更新日期：2017-10-01 00:00:00

abstract：:Vascular grafts are used to bypass damaged or diseased blood vessels. Bacterial cellulose (BC) has been studied for use as an off-the-shelf graft. Herein, we present a novel, cost-effective, method for the production of small caliber BC grafts with minimal processing or requirements. The morphology of the graft wall p...

journal_title：Macromolecular bioscience

authors： Leitão AF,Faria MA,Faustino AM,Moreira R,Mela P,Loureiro L,Silva I,Gama M

更新日期：2016-01-01 00:00:00

abstract：:The use of long-lasting polymer coatings on biodevice surfaces has been investigated to improve material-tissue interaction, minimize adverse effects, and enhance their functionality. Natural polymers, especially chitosan, are of particular interest due to their excellent biological properties, such as biocompatibilit...

journal_title：Macromolecular bioscience

authors： Souza Campelo C,Chevallier P,Loy C,Silveira Vieira R,Mantovani D

更新日期：2020-01-01 00:00:00

abstract：:In this work we report, compare and discuss the results obtained from fully atomistic molecular dynamics simulations of generations 4, 5, and 6 of PAMAM-based dendrimers having NH(3) and triethanolamine as cores, forming complexes with a short interfering RNA (siRNA) at different pH values and at physiological ionic ...

journal_title：Macromolecular bioscience

authors： Karatasos K,Posocco P,Laurini E,Pricl S

更新日期：2012-02-01 00:00:00

abstract：:The repair of large crushed or sectioned segments of peripheral nerves remains a challenge in regenerative medicine due to the complexity of the biological environment and the lack of proper biomaterials and architecture to foster reconstruction. Traditionally such reconstruction is only achieved by using fresh human ...

journal_title：Macromolecular bioscience

authors： Belanger K,Dinis TM,Taourirt S,Vidal G,Kaplan DL,Egles C

更新日期：2016-04-01 00:00:00

abstract：:Thermosensitive polymers enable externally controllable biomolecular interactions but hysteresis effects hamper the reversibility and repeated use of these materials. To quantify the temperature-dependent interactions and hysteresis effects, an optical adhesion assay based on poly(ethylene glycol) microgels (soft coll...

journal_title：Macromolecular bioscience

authors： Strzelczyk AK,Paul TJ,Schmidt S

更新日期：2020-10-01 00:00:00

abstract：:Poly(vinyl alcohol)-pyrene-anti-metadherin (PVA-Py-(Anti-MTDH)), a novel antibody based water soluble probe containing both fluorescent and target sites in the structure for in vitro imaging of breast cancer cells is reported here. Since breast cancer cells have an excess of MDTH protein expressed on the surface, a PV...

journal_title：Macromolecular bioscience

authors： Medine EI,Odaci D,Gacal BN,Gacal B,Sakarya S,Unak P,Timur S,Yagci Y

更新日期：2010-06-11 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is an important protein for wound healing and angiogenesis in tissue engineering, but the lack of a viable delivery system hampers its clinical application. This study aims to maintain the long-term controlled release of bFGF by utilizing a collagen/heparin bi-affinity multilayer ...

journal_title：Macromolecular bioscience

authors： Hao W,Han J,Chu Y,Huang L,Zhuang Y,Sun J,Li X,Zhao Y,Chen Y,Dai J

更新日期：2018-11-01 00:00:00

abstract：:Three different microbial wild-type strains are compared with respect to their potential as industrial scale polyhydroxyalkanoate (PHA) producers from the feed stock whey lactose. The halophilic archaeon Haloferax mediterranei as well as two eubacterial strains (Pseudomonas hydrogenovora and Hydrogenophaga pseudoflava...

journal_title：Macromolecular bioscience

authors： Koller M,Hesse P,Bona R,Kutschera C,Atlić A,Braunegg G

更新日期：2007-02-12 00:00:00

abstract：:Biopolymers are an attractive class of compounds for being used in biomedical applications as they are widely available from biomass. Their drawback is the lack of mechanical stability and the ability to tune this properly. Covalent chemical cross-linking is an often used approach but it limits usability due to legisl...

journal_title：Macromolecular bioscience

authors： Kühn PT,Meijer TL,Schiavon I,van Poll M,van Aken J,Groen S,Kuijer R,van Kooten TG,van Rijn P

更新日期：2016-11-01 00:00:00

abstract：:Transparent, biodegradable, mechanically robust, and surface-patterned silk films were evaluated for the effect of surface morphology on human corneal fibroblast (hCF) cell proliferation, orientation, and ECM deposition and alignment. A series of dimensionally different surface groove patterns were prepared from optic...

journal_title：Macromolecular bioscience

authors： Gil ES,Park SH,Marchant J,Omenetto F,Kaplan DL

更新日期：2010-06-11 00:00:00

abstract：:Novel temperature-sensitive poly(N-isopropylacrylamide)/amine-terminated polyamidoamine dendrimer G6-NH2 hydrogels with fast responsive properties were synthesized by forming semi-interpenetrating polymeric networks. In contrast to the conventional PNIPA hydrogel, these new gels showed rapid shrinking rate at the temp...

journal_title：Macromolecular bioscience

authors： Zhang JT,Huang SW,Zhuo RX

更新日期：2004-06-25 00:00:00