Silk fibroin/gelatin blend films crosslinked with enzymes for biomedical applications.


:Microbial transglutaminase (mTG) and mushroom tyrosinase (MT) are used to crosslink B. mori silk fibroin/gelatin (SF/G) films. Crosslinked and uncrosslinked SF/G films show no phase separation. The thermal behavior and the conformational structure of SF/G films are strongly affected by blending and enzymatic treatment. Formation of high thermally stable crosslinked macromolecular species is observed, suggesting the occurrence of strong intermolecular interactions between the two polymers as confirmed by FT-Raman spectroscopy. Preliminary in vitro tests show that MT-crosslinked blends with G amounts ≥40% and mTG-crosslinked SF/G 60/40 films support C2C12 cardiomyocyte adhesion and proliferation.


Macromol Biosci


Taddei P,Chiono V,Anghileri A,Vozzi G,Freddi G,Ciardelli G




Has Abstract


2013-11-01 00:00:00












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    journal_title:Macromolecular bioscience

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    authors: Tao L,Chou WC,Tan BH,Davis TP

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    authors: Gurnani P,Sanchez-Cano C,Abraham K,Xandri-Monje H,Cook AB,Hartlieb M,Lévi F,Dallmann R,Perrier S

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    authors: Cavalieri F,Chiessi E,Finelli I,Natali F,Paradossi G,Telling MF

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    journal_title:Macromolecular bioscience

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    authors: Gil ES,Park SH,Marchant J,Omenetto F,Kaplan DL

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    authors: Rachmawati R,Woortman AJ,Loos K

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    authors: Shi X,Shi Z,Wang D,Ullah MW,Yang G

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    authors: Chattopadhyay S,Heine ET,Keul H,Möller M

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    pub_type: 杂志文章,评审


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    authors: Wang X,Liu L,Luo Y,Shi H,Li J,Zhao H

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    authors: Wongpanit P,Tabata Y,Rujiravanit R

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  • Magnetically Responsive Polymeric Microparticles for the Triggered Delivery of a Complex Mixture of Human Placental Proteins.

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    authors: Frick SU,Bacher N,Baier G,Mailänder V,Landfester K,Steinbrink K

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    pub_type: 杂志文章


    authors: Chan-Park MB,Zhu AP,Shen JY,Fan AL

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    pub_type: 杂志文章


    authors: Suzuki Y,Esumi Y,Koshino H,Doi Y

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章


    authors: Wan Y,Feng G,Shen FH,Balian G,Laurencin CT,Li X

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章


    authors: Quaglia F,Ostacolo L,Nese G,De Rosa G,La Rotonda MI,Palumbo R,Maglio G

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章


    authors: Alasino RV,Bianco ID,Vitali MS,Zarzur JA,Beltramo DM

    更新日期:2007-09-11 00:00:00

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章


    authors: Kim J,Kim KS,Park SJ,Na K

    更新日期:2015-08-01 00:00:00

  • Micro-engineered 3D scaffolds for cell culture studies.

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章,评审


    authors: Greiner AM,Richter B,Bastmeyer M

    更新日期:2012-10-01 00:00:00

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    journal_title:Macromolecular bioscience

    pub_type: 杂志文章


    authors: Prabaharan M,Mano JF

    更新日期:2005-10-20 00:00:00