Temperature-sensitive polyamidoamine dendrimer/poly(N-isopropylacrylamide) hydrogels with improved responsive properties.

abstract：:The biorecognition-based control of attachment/detachment of MCF-7 cancer cells from polymer-coated surfaces is demonstrated. A glass surface is coated with a thermoresponsive statistical copolymer of poly(N-isopropylacrylamide-co-acrylamide) [p(NIPAm-co-Am)], which is end-capped with the Gly-Arg-Gly-Asp-Ser (GRGDS) p...

journal_title：Macromolecular bioscience

authors： Brunato S,Mastrotto F,Bellato F,Garofalo M,Göddenhenrich T,Mantovani G,Alexander C,Gross S,Salmaso S,Caliceti P

更新日期：2020-11-04 00:00:00

abstract：:Thermosensitive macroporous scaffolds of poly(N-isopropylacrylamide) (polyNIPA) loaded with chitosan/bemiparin nanoparticles are prepared by the free radical polymerization in cryogenic conditions. Chitosan/bemiparin nanoparticles of 102 ± 6.5 nm diameter are prepared by complex coacervation and loaded into polyNIPA c...

journal_title：Macromolecular bioscience

authors： Peniche H,Reyes-Ortega F,Aguilar MR,Rodríguez G,Abradelo C,García-Fernández L,Peniche C,San Román J

更新日期：2013-11-01 00:00:00

abstract：:We recently discovered that poly(aspartate) (PAA) hydrolase-1 from Pedobacter sp. KP-2 has a unique property of specifically cleaving the amide bond between β-aspartate units in thermally synthesized PAA (tPAA). In the present study, the enzymatic synthesis of poly(α-ethyl β-aspartate) (β-PAA) was performed by taking ...

journal_title：Macromolecular bioscience

authors： Hiraishi T,Masuda E,Miyamoto D,Kanayama N,Abe H,Maeda M

更新日期：2011-02-11 00:00:00

abstract：:This study investigates the structural features of porcine gastric mucin (PGM) in aqueous dispersions and its interactions with water-soluble polymers (poly(acrylic acid) (PAA), poly(methacrylic acid) (PMAA), poly(ethylene oxide), and poly(ethylene glycol)) using isothermal titration calorimetry, turbidimetric titrati...

journal_title：Macromolecular bioscience

authors： Albarkah YA,Green RJ,Khutoryanskiy VV

更新日期：2015-11-01 00:00:00

abstract：:We report the self-assembly of a series of amphiphilic diblock copolymers comprising a biocompatible, hydrophilic block, poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and a pH-sensitive block, poly(2-(diisopropylamino)ethyl methacrylate) (PDPA), into a dispersion of colloidally stable, nanometer-sized polymers...

journal_title：Macromolecular bioscience

authors： Lomas H,Du J,Canton I,Madsen J,Warren N,Armes SP,Lewis AL,Battaglia G

更新日期：2010-05-14 00:00:00

abstract：:The design of a novel polymer-modified overlayer composed of PPAPE and GPMS on a silicon wafer for immobilization of DNA molecules is described. After hydroxylation of Si(100) surfaces, GPMS molecules were self-assembled onto these surfaces. PPAPE molecules were then covalently attached to the epoxy-terminated surface...

journal_title：Macromolecular bioscience

authors： Demirel GB,Coşkun S,Kalkan M,Caykara T

更新日期：2009-05-13 00:00:00

abstract：:This study aims to develop an effective method to control motile microorganisms and enable their manipulation as functional 'live micro/nano robots'. A novel strategy based on Fe3 O4 nanoparticle-doped alginate hydrogel is developed to fashion an artificial extracellular matrix (ECM) for microbial cells (e.g., Sacchar...

journal_title：Macromolecular bioscience

authors： Shi X,Shi Z,Wang D,Ullah MW,Yang G

更新日期：2016-10-01 00:00:00

abstract：:Interaction of conjugated polymers with liposomes is an attractive approach that benefits from both systems' characteristics such as electroactivity and enhanced interaction with cells. Conjugated polymer-liposome complexes have been investigated for bioimaging, drug delivery, and photothermal therapy. Their fabricati...

journal_title：Macromolecular bioscience

authors： Eslami M,Zeglio E,Alosaimi G,Yan Y,Ruprai H,Macmillan A,Seidel J,Lauto A,Joukhdar H,Rnjak-Kovacina J,Mawad D

更新日期：2020-11-01 00:00:00

abstract：:Microparticle drug carriers made of biodegradable functional polyesters were produced. The polyesters consist of a poly(ε-caprolactone) backbone bearing pendant acryloyloxy and methacryloyloxy groups. Stable microparticles were prepared via an oil/water emulsion-solvent evaporation technique eventually combined with a...

journal_title：Macromolecular bioscience

authors： Vaida C,Mela P,Kunna K,Sternberg K,Keul H,Möller M

更新日期：2010-08-11 00:00:00

abstract：:Integration of electrogenic microorganisms remains a challenge in biofuel cell technology. Here, synthetic biocomposites ("artificial biofilms") are proposed. Bacteria (Shewanella oneidensis) are embedded in a hydrogel matrix (poly(vinyl alcohol)) via wet- and electrospinning, creating fibers and nonwoven gauzes. The ...

journal_title：Macromolecular bioscience

authors： Kaiser P,Reich S,Leykam D,Willert-Porada M,Greiner A,Freitag R

更新日期：2017-07-01 00:00:00

abstract：:Currently, there is no gadolinium-based contrast agent available for conventional magnetic resonance imaging (MRI) detection of amyloidal beta (Aβ) plaques in Alzheimer's disease (AD). Its timely finding would be vital for patient survival and quality of life. Curcumin (CUR), a common Indian spice effectively binds to...

journal_title：Macromolecular bioscience

authors： Patil R,Gangalum PR,Wagner S,Portilla-Arias J,Ding H,Rekechenetskiy A,Konda B,Inoue S,Black KL,Ljubimova JY,Holler E

更新日期：2015-09-01 00:00:00

abstract：:Melanin is an effective absorber of light and can extend to near infrared (NIR) regions. In this study, a natural melanin is presented as a photothermal therapeutic agent (PTA) because it provides a good photothermal conversion efficiency, shows biodegradability, and does not induce long-term toxicity during retention...

journal_title：Macromolecular bioscience

authors： Kim M,Kim HS,Kim MA,Ryu H,Jeong HJ,Lee CM

更新日期：2017-05-01 00:00:00

abstract：:The remedy for infected chronic wounds such as diabetic foot ulcers is more complicated particularly in the case of patients with an inefficient immune system. Also, fighting against microbial infections in the wound site by available antibiotics may not be effective because of emerging antibiotic resistance propertie...

journal_title：Macromolecular bioscience

authors： Alavi M,Nokhodchi A

更新日期：2020-04-01 00:00:00

abstract：:For use in micro-patterned scaffolds in tissue engineering, novel diacrylated triblock macromers (PLA-b-PCL-b-PLA, PGA-b-PCL-b-PGA and PCL-b-PEO-b-PCL) were synthesized and characterized by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (NMR) and gel permeation chromatography (...

journal_title：Macromolecular bioscience

authors： Chan-Park MB,Zhu AP,Shen JY,Fan AL

更新日期：2004-07-14 00:00:00

abstract：:The synthesis of a zwitterionic polymer, poly-sulfobetaine (poly-SPB), which shows remarkable efficiency in the suppression of insulin aggregation is described. Hydrophobic modification of the polymer results in almost complete inhibition at very low polymer concentrations. Further studies reveal that these polymers f...

journal_title：Macromolecular bioscience

authors： Rajan R,Suzuki Y,Matsumura K

更新日期：2018-06-01 00:00:00

abstract：:The next-generation sutures should provide in situ monitoring of wound condition such as temperature while reducing surgical site infection during wound closure. In this study, functionalized nanodiamond (FND) and reduced graphene oxide (rGO) into biodegradable polycaprolactone (PCL) are incorporated to develop a new ...

journal_title：Macromolecular bioscience

authors： Houshyar S,Bhattacharyya A,Khalid A,Rifai A,Dekiwadia C,Kumar GS,Tran PA,Fox K

更新日期：2021-01-12 00:00:00

abstract：:Aggregation of denatured or unfolded proteins establishes a large energy barrier to spontaneous recovery of protein form and function following traumatic injury, tissue cryopreservation, and biopharmaceutical storage. Some tissues utilize small heat shock proteins (sHSPs) to prevent irreversible aggregation, which all...

journal_title：Macromolecular bioscience

authors： Poellmann MJ,Sosnick TR,Meredith SC,Lee RC

更新日期：2017-02-01 00:00:00

abstract：:In this paper, a novel composite hydrogel was prepared by the use of dialdehyde konjac glucomannan (DAK) as macromolecular cross-linking agent for chitosan (CS). This biocompatible material cross-links and gels in minutes. The structure and morphology were characterized by various analyses. The results indicate that t...

journal_title：Macromolecular bioscience

authors： Yu H,Lu J,Xiao C

更新日期：2007-09-11 00:00:00

abstract：:Formulation of docetaxel (DOC), a hydrophobic anticancer drug, was successfully achieved in poly(gamma-benzyl L-glutamate)-block-hyaluronan polymersomes using a simple and reproducible nanoprecipitation method. The prepared DOC loaded polymersomes (PolyDOC) was stable either in solution or in a lyophilized form, and s...

journal_title：Macromolecular bioscience

authors： Upadhyay KK,Bhatt AN,Castro E,Mishra AK,Chuttani K,Dwarakanath BS,Schatz C,Le Meins JF,Misra A,Lecommandoux S

更新日期：2010-05-14 00:00:00

abstract：:PCL microspheres featuring a macroporous morphology and a bone-bioactive surface have been prepared. 'Camphene' was introduced to generate pores within the microsphere network. The pore size was variable from a few to tens to hundreds of microm depending on the Camphene/PCL ratio. Macropores (with sizes >50 microm) co...

journal_title：Macromolecular bioscience

authors： Hong SJ,Yu HS,Kim HW

更新日期：2009-07-07 00:00:00

abstract：:A gold standard for esophagus reconstruction is not still available. The present work aims to design a polymer patch combining synthetic polylactide-co-polycaprolacton and chitosan biopolymers, tailoring patch properties to esophageal tissue characteristics by a temperature-induced precipitation method, to get multila...

journal_title：Macromolecular bioscience

authors： Dorati R,De Trizio A,Marconi S,Ferrara A,Auricchio F,Genta I,Modena T,Benazzo M,Benazzo A,Volpato G,Conti B

更新日期：2017-06-01 00:00:00

abstract：:A simple, robust one pot procedure for the preparation of waterborne multifunctional poly(vinyl amine)s (PVAms) is presented. By post-polymerization modification of PVAm with a bifunctional coupler and functional couplers cationic, reactive azetidinium groups, and alkyl chains are introduced in the side chains of PVAm...

journal_title：Macromolecular bioscience

authors： Chattopadhyay S,Heine ET,Keul H,Möller M

更新日期：2014-08-01 00:00:00

abstract：:The enzymatic transformation into an oligomer was carried out with the objective of developing the chemical recycling of bacterial polyesters. Poly(R-3-hydroxyalkanoate)s (PHAs), such as poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyhexanoate)] and poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyvalerate)], were degraded ...

journal_title：Macromolecular bioscience

authors： Kaihara S,Osanai Y,Nishikawa K,Toshima K,Doi Y,Matsumura S

更新日期：2005-07-14 00:00:00

abstract：:Nanotechnology is finding ever increasing application in the life science arena where nanoparticles can be used to deliver cargoes in cells. However, a clear understanding of the relationship between the chemical properties of the particle and its uptake efficiency is lacking. Herein, the effects on particle cellular ...

journal_title：Macromolecular bioscience

authors： Thielbeer F,Johansson EM,Chankeshwara SV,Bradley M

更新日期：2013-06-01 00:00:00

abstract：:The preclinical development of nanomedicines raises several challenges and requires a comprehensive characterization. Among them is the evaluation of the biodistribution following systemic administration. In previous work, the biocompatibility and in vitro targeting ability of a glycol chitosan (GC) based nanogel have...

journal_title：Macromolecular bioscience

authors： Pereira P,Correia A,Gama FM

更新日期：2016-03-01 00:00:00

abstract：:3D printing has become an essential part of bone tissue engineering and attracts great attention for the fabrication of bioactive scaffolds. Combining this rapid manufacturing technique with chemical precipitation, biodegradable 3D scaffold composed of polymer matrix (polylactic acid and polyethylene glycol), ceramics...

journal_title：Macromolecular bioscience

authors： Li X,Wang Y,Wang Z,Qi Y,Li L,Zhang P,Chen X,Huang Y

更新日期：2018-06-01 00:00:00

abstract：:In search for effective non-viral gene vectors for the delivery of siRNA, a copolymer was designed and synthesized by grafting hydrophobic poly(gamma-benzyl L-glutamate) segment (PBLG) to hyperbranched polyethylenimine (PEI-PBLG). PEI-PBLG could efficiently deliver siRNA to cells to silence the targeted gene. Markedly...

journal_title：Macromolecular bioscience

authors： Chen J,Tian H,Guo Z,Xia J,Kano A,Maruyama A,Jing X,Chen X

更新日期：2009-12-08 00:00:00

abstract：:In pluripotent stem cell differentiation, embryoid bodies (EBs) provide a three-dimensional [3D] multicellular precursor in lineage specification. The internal structure of EBs is not well characterized yet is predicted to be an important parameter to differentiation. Here, we use custom SU-8 molds to generate transpa...

journal_title：Macromolecular bioscience

authors： Tomov ML,Olmsted ZT,Paluh JL

更新日期：2015-07-01 00:00:00

abstract：:The use of sugar-functionalized polyplexes as a nonviral gene delivery vector with lower cytotoxicity than the well-known polymeric carrier branched polyethyleneimine (BPEI) is investigated. The substitution of primary amine groups in the BPEI chains with lactose residues leads to larger polyplexes, presumably due to ...

journal_title：Macromolecular bioscience

authors： Albuquerque LJC,Alavarse AC,Carlan da Silva MC,Zilse MS,Barth MT,Bellettini IC,Giacomelli FC

更新日期：2018-02-01 00:00:00

abstract：:Recently, the Foresight Institute has pronounced six economic challenges that can be addressed through the progress of nanotechnology. One of these is the health and longevity of human life. Amongst applications anticipated to provide a solution to this challenge, gene therapy appears to be particularly promising. In ...

journal_title：Macromolecular bioscience

authors： Lamarre B,Ryadnov MG

更新日期：2011-04-08 00:00:00