Abstract:
:The distribution of creatine kinase BB-isoenzyme in the human central nervous system (CNS) was investigated immunohistochemically and the findings were compared with the distributions of tubulin and astroprotein. Creatine kinase BB-isoenzyme existed both in neurons and astrocytes, and was universally distributed within the CNS. Tubulin was visualized only in the neuronal elements, namely perikarya, dendrites and axons, while astroprotein was exclusively visualized in astrocytes. A combination of immunohistochemistry for structural and soluble proteins may be a useful tool for the investigation of pathophysiological conditions within the CNS.
journal_name
Brain Resjournal_title
Brain researchauthors
Yoshimine T,Morimoto K,Homburger HA,Yanagihara Tdoi
10.1016/0006-8993(83)91338-0subject
Has Abstractpub_date
1983-04-11 00:00:00pages
101-8issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(83)91338-0journal_volume
265pub_type
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