Mood responses of remitted schizophrenics to methylphenidate infusion.

abstract：:During the third week of life, a hyperactive period for laboratory rat, the occurrence of 8 behavioral categories was recorded in individual littermates transferred to a novel environment. Neonatal destruction of the catecholaminergic system by intraventricular injection of 6-OH-DA resulted in increased motor activity...

journal_title：Psychopharmacology

authors： Stoof JC,Duijkstra H,Hillegers JP

更新日期：1978-04-28 00:00:00

abstract：:Central dopaminergic transmission has been implicated in memory processes. The present experiments examined the effects of several direct acting dopaminergic agents on performance of a delayed-non-match-to-sample radial arm maze task. Preadministration of apomorphine (D1-D2 agonist; 0.25, 0.5, and 1.0 mg/kg), quinpiro...

journal_title：Psychopharmacology

authors： Chrobak JJ,Napier TC

更新日期：1992-01-01 00:00:00

abstract：:Measurements of the amplitude and latency of the P3b component of the event-related potential (ERP), simple reaction time (SRT) and four psychomotor tests (VAS, DSST, DSp and CFF) were made on 12 male subjects (aged 19-24 years) 1.0-1.5 and 4.0-4.5 h after single oral doses of triprolidine (7.5 mg), terfenadine (60 mg...

journal_title：Psychopharmacology

authors： Swire FM,Marsden CA,Barber C,Birmingham AT

更新日期：1989-01-01 00:00:00

abstract：RATIONALE:(1S,3aS)-8-(2,3,3,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198), a non-peptidic agonist for the opioid receptor-like1 (ORL1) receptor, exhibits anxiolytic properties in stressful conditions. OBJECTIVE:The present study was aimed at evaluating whether activation of ...

journal_title：Psychopharmacology

authors： Ciccocioppo R,Biondini M,Antonelli L,Wichmann J,Jenck F,Massi M

更新日期：2002-05-01 00:00:00

abstract：:The place-preference paradigm was evaluated as a measure of morphine's positive reinforcing properties. Previous place-preference studies obtained a morphine place preference of 26%-63%. In order to examine whether differences in procedure may account for this scatter, the present experiment investigated whether there...

journal_title：Psychopharmacology

authors： Blander A,Hunt T,Blair R,Amit Z

更新日期：1984-01-01 00:00:00

abstract：:Nine depressed patients were treated with alaproclate, a selective 5-HT uptake inhibitor, for 3 weeks in a dose of 400 mg daily. The pupillary responses to tyramine, phenylephrine, and pilocarpine eye drops were measured on consecutive days before, after 1 week and after 3 weeks of treatment. The tyramine-induced mydr...

journal_title：Psychopharmacology

authors： Thompson C,Checkley SA

更新日期：1985-01-01 00:00:00

abstract：RATIONALE:The efficacy of methadone for treating heroin dependence derives, in part, from suppression of opiate withdrawal and attenuation of the effects of heroin. OBJECTIVES:The purpose of this double-blind, within-subject, inpatient study was to determine whether larger doses of methadone, which are more effective ...

journal_title：Psychopharmacology

authors： Donny EC,Walsh SL,Bigelow GE,Eissenberg T,Stitzer ML

更新日期：2002-05-01 00:00:00

abstract：:The name of Hayley Treloar Padovano was incorrectly tagged in the original version of this article. Instead of Padovano as family name and Hayley Treloar as given name, it should be Hayley as given name and Treloar Padovano as family name. Correct presentation of author name when online should be Treloar Padovano H. ...

journal_title：Psychopharmacology

authors： Mereish EH,Treloar Padovano H,Wemm S,Miranda R Jr

更新日期：2018-09-01 00:00:00

abstract：RATIONALE:The present series of experiments was conducted in order to assess the nature of dopaminergic modulation of the acoustic startle response using agonists and antagonists specific for dopamine D1 and D2 receptors. OBJECTIVES:The objective of the present study was to demonstrate an enhancement of the acoustic s...

journal_title：Psychopharmacology

authors： Meloni EG,Davis M

更新日期：1999-06-01 00:00:00

abstract：RATIONALE:3,4-Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone abused for its cocaine-like psychostimulant effects in "bath salts" products. While there are currently no pharmacotherapies for MDPV abuse, rodent studies suggest immunotherapy may offer a feasible treatment option. OBJECTIVES:These studies test...

journal_title：Psychopharmacology

authors： McClenahan SJ,Gunnell MG,Owens SM,Fantegrossi WE

更新日期：2020-09-01 00:00:00

abstract：:Muscimol, a structural analog of GABA, significantly potentiated pilocarpine-induced analgesia in rats, but failed to alter pilocarpine-induced catalepsy. It also failed to affect pilocarpine-elicited increase in homovanillic acid levels in the striatum. These findings suggest that the potentiation of pilocarpine-indu...

journal_title：Psychopharmacology

authors： Naik SR,Kelkar MR,Amladi SR,Sheth UK

更新日期：1981-01-01 00:00:00

abstract：:A paradigm for assessing benzodiazepine receptor sensitivity was developed using intravenous midazolam in normal volunteers. After administration of incremental doses of midazolam, alterations in saccadic eye movement parameters and psychological self ratings were assessed. Significant changes included dose-dependent ...

journal_title：Psychopharmacology

authors： Ball DM,Glue P,Wilson S,Nutt DJ

更新日期：1991-01-01 00:00:00

abstract：RATIONALE:Although the subjective effects of caffeine abstinence, acute and chronic administration, and tolerance are well described, the corresponding neurophysiological effects are not. OBJECTIVES:Caffeine withdrawal, acute caffeine effects, caffeine tolerance, and net beneficial effects of chronic caffeine administ...

journal_title：Psychopharmacology

authors： Sigmon SC,Herning RI,Better W,Cadet JL,Griffiths RR

更新日期：2009-07-01 00:00:00

abstract：RATIONALE:Quitting smoking is often very challenging, leading to frequent relapse. Exposure to acute and chronic stress during abstinence increases the likelihood of relapse to smoking. In rodents, stress acutely reinstates nicotine seeking after extinction of nicotine self-administration (SA). However, whether reacqui...

journal_title：Psychopharmacology

authors： Yu G,Chen H,Sharp BM

更新日期：2014-08-01 00:00:00

abstract：RATIONALE:Mice are useful tools for dissecting genetic and environmental factors in relation to the study of attention and impulsivity. The five-choice serial reaction time task (5CSRTT) paradigm has been well established in rats, but its transferability to mice is less well documented. OBJECTIVES:This study aims to s...

journal_title：Psychopharmacology

authors： Sanchez-Roige S,Peña-Oliver Y,Stephens DN

更新日期：2012-01-01 00:00:00

abstract：:The importance of brain noradrenaline synthesis and receptor activation for the hyperkinesia induced by carbidopa plus L-Dopa in reserpine-treated or normal mice was analyzed in four different models. After pretreatment with reserpine and the monoamine oxidase inhibitor nialamide, the hyperkinesia induced by L-Dopa (2...

journal_title：Psychopharmacology

authors： Andén NE,Strömbom U,Svensson TH

更新日期：1977-11-15 00:00:00

abstract：RATIONALE:Varenicline is believed to work, in part, by reducing craving responses to smoking cues and by reducing general levels of craving; however, these hypotheses have never been evaluated with craving assessed in the natural environments of treatment-seeking smokers. OBJECTIVES:Ecological momentary assessment pro...

journal_title：Psychopharmacology

authors： Gass JC,Wray JM,Hawk LW,Mahoney MC,Tiffany ST

更新日期：2012-09-01 00:00:00

abstract：:Experiments assessed the development of tolerance to morphine stimulus control during treatment with selected maintenance doses of morphine. Separate groups of rats were trained to discriminate saline and either 3.2 mg/kg or 5.6 mg/kg morphine under fixed-ratio schedules of food delivery. Dose-response functions for g...

journal_title：Psychopharmacology

authors： Young AM,Sannerud CA,Steigerwald ES,Doty MD,Lipinski WJ,Tetrick LE

更新日期：1990-01-01 00:00:00

abstract：:Pigeons were trained to acquire a new 4-response sequence in each session by pecking three keys in a predetermined order. The key color varied for each step under the chained schedule, but there was only one key color under the tandem schedule. Under the reset contingency, incorrect responses produced a reset of the 4...

journal_title：Psychopharmacology

authors： Harting J,Mcmillian DE

更新日期：1976-09-29 00:00:00

abstract：:Sixteen healthy volunteers were administered midazolam followed by placebo or the benzodiazepine antagonist, flumazenil, in a double-blind, cross-over study. Flumazenil reversed midazolam-induced sedation on the subjective, psychophysiological and motor indices used. In contrast, there was little evidence of any rever...

journal_title：Psychopharmacology

authors： Curran HV,Birch B

更新日期：1991-01-01 00:00:00

abstract：RATIONALE:Although the behavioral effects of systemic injection of lipopolysaccharide (LPS) have been extensively investigated, the modulation of these effects by natural environmental factors has received little attention. OBJECTIVES:The present study investigated whether or not locomotor activity reductions and the ...

journal_title：Psychopharmacology

authors： Franklin AE,Engeland CG,Kavaliers M,Ossenkopp KP

更新日期：2003-12-01 00:00:00

abstract：RATIONALE:Second-generation antipsychotics occupy dopamine D2 receptors and act as antagonists or partial agonists at these receptors. While these drugs alleviate positive symptoms in patients with schizophrenia, they are less effective for treating cognitive deficits and negative symptoms. Dopamine D3 receptors are hi...

journal_title：Psychopharmacology

authors： Girgis RR,Slifstein M,D'Souza D,Lee Y,Periclou A,Ghahramani P,Laszlovszky I,Durgam S,Adham N,Nabulsi N,Huang Y,Carson RE,Kiss B,Kapás M,Abi-Dargham A,Rakhit A

更新日期：2016-10-01 00:00:00

abstract：:Carbachol, muscarine, eserine and neostigmine injected into the cerebral ventricles of conscious cats evoked emotional behaviour with aggression, autonomic and motor phenomena as well as clonic-tonic convulsions. The main and the most impressive feature of the gross behavioural effects of intraventricular carbachol, m...

journal_title：Psychopharmacology

authors： Beleslin DB,Samardzić R

更新日期：1979-04-11 00:00:00

abstract：:Patients taking lithium often report difficulties in concentration, memory, learning, and attention and many of these complaints are verified on psychometric testing. Laboratory tests of cognitive functions in healthy volunteers on chronic lithium demonstrate that disruptions in memory-learning processes are apparent ...

journal_title：Psychopharmacology

authors： Weingartner H,Rudorfer MV,Linnoila M

更新日期：1985-01-01 00:00:00

abstract：RATIONALE:Approximately 20 million adults in the USA have an alcohol use disorder (AUD). There are clinical and preclinical data suggesting that psychedelics may have benefits for AUD. OBJECTIVE:To investigate the effects of the synthetic psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) on the behavioral effects of e...

journal_title：Psychopharmacology

authors： Oppong-Damoah A,Curry KE,Blough BE,Rice KC,Murnane KS

更新日期：2019-12-01 00:00:00

abstract：:It was shown previously that behavioural effects of apomorphine (locomotor activation and stereotyped behaviour) can be conditioned when they are associated with well-defined environmental stimuli. In the present study, the hypothesis was tested that glutamatergic mechanisms play an important role either in formation ...

journal_title：Psychopharmacology

authors： Welsch-Kunze S,Kuschinsky K

更新日期：1990-01-01 00:00:00

abstract：:Keypecking in one group of pigeons was maintained under schedules in which food was presented only when a specified number of responses was followed by a 30-s pause without a response. d-Amphetamine and pentobarbital increased low rates of responding (and, thus, decreased food presentation) only after initial injectio...

journal_title：Psychopharmacology

authors： Smith JB,McKearney JW

更新日期：1977-07-18 00:00:00

abstract：:Rhesus monkeys were trained in a discrete-trials choice procedure and allowed to choose between intravenous injections of cocaine (0.01-1.0 mg/kg/injection) and food presentation (1 or 4 pellets; 1 g/pellet) during daily 7-h experimental sessions. When each reinforcer was available under a fixed-ratio (FR) 30 schedule...

journal_title：Psychopharmacology

authors： Nader MA,Woolverton WL

更新日期：1992-01-01 00:00:00

abstract：:Roxindole is a potent autoreceptor-selective dopamine agonist with additional properties as a serotonin reuptake inhibitor and 5-HT1A agonist. In order to get more insight into its mode of action in various psychiatric populations, we evaluated the effects of subchronic roxindole treatment on pituitary and adrenal hor...

journal_title：Psychopharmacology

authors： Gründer G,Wetzel H,Hillert A,Jochum E,Hiemke C,Benkert O

更新日期：1995-02-01 00:00:00

abstract：:The effects of benzodiazepine (BZ) antagonists on operant behavior were examined in rats chronically administered a low dose of diazepam (DZ). The low maintenance dose of DZ (5 mg/kg twice daily) was selected as more closely associated with its anxiolytic effects than the higher treatment doses previously used to stud...

journal_title：Psychopharmacology

authors： Lucki I,Kucharik RF

更新日期：1990-01-01 00:00:00