Abstract:
:In this work, the in vivo degradation and tissue compatibility of a novel class of inherently fluorescent copolyanhydrides, P(dCPS:SA), were investigated. It was found that the degradation of the copolyanhydrides increased with the increase of SA content in the copolymers. The in vivo degradation rate of the copolymers was slower than that studied in vitro. A surface erosion characteristic of the copolyanhydrides was revealed by SEM and fluorescent microscopy. Mild inflammatory reactions were observed on days 6 and 10 after implantation for all the studied copolymers. By the end of 30 d, there were almost no inflammation reactions taking place.
journal_name
Macromol Bioscijournal_title
Macromolecular bioscienceauthors
Fan J,Li Y,Jiang H,Tang G,Wang Ldoi
10.1002/mabi.200700280subject
Has Abstractpub_date
2008-05-13 00:00:00pages
384-92issue
5eissn
1616-5187issn
1616-5195journal_volume
8pub_type
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