Abstract:
:The core gene promoter of duck hepatitis B virus (DHBV) has been localized and an enhancer element has been found in a region of the DHBV genome immediately upstream of the core promoter. This enhancer was able to activate expression from both the core promoter and the S promoter of DHBV, as well as from the heterologous thymidine kinase and simian virus 40 early promoters, but not from the DHBV PreS promoter, which was active both in the absence and in the presence of the enhancer. The activity of the enhancer showed a preference for cell cultures of hepatic origin, suggesting a possible tissue preference in vivo.
journal_name
Virologyjournal_title
Virologyauthors
Liu C,Condreay LD,Burch JB,Mason Wdoi
10.1016/0042-6822(91)90841-xsubject
Has Abstractpub_date
1991-09-01 00:00:00pages
242-52issue
1eissn
0042-6822issn
1096-0341journal_volume
184pub_type
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