Abstract:
:In this issue of Neuron, Wang et al. demonstrate that both cell-intrinsic and -extrinsic factors restrict the myelination of newly regenerated axons. Pharmalogical targeting of GPR17 signaling in oligodendrocyte precursor cells (OPCs) and microglial inhibition of oligodendrocyte maturation together promote robust myelination of regenerated axons after CNS injury.
journal_name
Neuronjournal_title
Neuronauthors
Hilton BJ,Bradke Fdoi
10.1016/j.neuron.2020.10.033subject
Has Abstractpub_date
2020-12-09 00:00:00pages
797-798issue
5eissn
0896-6273issn
1097-4199pii
S0896-6273(20)30857-6journal_volume
108pub_type
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